Sentences with phrase «cell membrane receptors»

Rather than fight the infection after it invades, particular changes to cell membrane receptors can completely prevent plague bacteria from infecting cells.

Prof. De Meyts assures that «Prof. Maruyama makes a convincing case that this [dimerization] model is incorrect, and that in fact, numerous cell membrane receptors are pre-dimerized in the membrane and are activated allosterically by ligand binding.»

Palovarotene is a retinoic acid receptor (RAR) agonist, a molecule that binds a cell membrane receptor to trigger molecular events that regulate cell function.

In its active form, it functions to regulate levels of heparan sulfate, a kind of generic cell membrane receptor.

Not exact matches

Cinnamon helps our body to stabilize blood sugar by de-inflaming the cell membranes and enhancing insulin receptor activity.

These protein and fat sources are extraordinarily critical for rebuilding healthy cell membranes with normalized insulin receptor activity.

Two protein receptors (yellow, red) float in a cell membrane's lipid rafts (orange), which play a role in antidepressants» delay.

The membrane wrapping around the virus is coated with proteins that bind to cell receptors.

These receptors are found in the cell membrane and handle the communication between the outside and the inside.

The key actors here likely are mu - opioid receptors, molecules on cell membranes that allow opioids to bind to them and interact with the cell itself, he says.

If the three - dimensional structures of the herb elements are elucidated, and a database of them can be established, it may facilitate computer - assisted imitation of docking between the herb element and physiologically important cell membrane proteins such as receptors, ion channels, and transporters.

They also have varying effects if they act on different receptors — proteins in cell membranes that bind neurotransmitters and control cell responses.

Studying these receptor molecules in detail is extremely difficult, because they almost always stop working if removed from the cell membrane.

The key discovery made by the CSHL team is that FER is able to activate a receptor on the surface of ovarian cells «from below,» as it were — by interacting with a portion of the receptor that penetrates the cell membrane and plunges into the cytoplasm.

They discovered that those with the disorder had mutations on a specific gene, called GPR54, which is known to produce a receptor in cell membranes.

The IFNGR receptor is one of these membrane proteins and undertakes to activate genes involved in a huge variety of cell processes, including defence against pathogens and cancer.

(Breast cancer is categorized and treated based on the presence or absence of three hormone receptors displayed on the outer membranes of cells.

The toxins overcome the cell membrane by binding to a surface receptor, which conveys them into the cell's interior.

By binding to the surface receptor, the toxins are able to overcome the cell membrane.

THC works by binding to the corresponding cannabinoid - 1 (CB1) receptors, which are located in the cell membrane and are present in large numbers in the central and peripheral nervous system.

The MSRs were then coated with lipids that formed a thin supported lipid bilayer (SLB), which resembles the outer membrane of APCs and that the researchers then functionalized with a pair of T cell - stimulating antibodies that remain mobile in the lipid layer and can bind to receptor / co-receptor molecules on the surface of T cells.

Specifically, the bipolar neurons expressed more genes for membrane receptors and ion channels than non-bipolar cells, particularly those receptors and channels involved in the sending and receiving of calcium signals between cells.

One way to do this is to make the protein in a bacterial cell and reconstitute it in nanodiscs, which are water friendly, membrane - like structures that the receptor can reside in.

PKA phosphorylates IP3 receptors located on cell membranes, inducing them to release intracellular stores of calcium ions.

We show that β - arrestins coordinate both processes by recruiting PDEs to activated β2 - adrenergic receptors in the plasma membrane of mammalian cells.

When the presynaptic neuron registers an influx of calcium ions, carrying the electrical surge of the action potential, vesicles that store neurotransmitters fuse to the cell's membrane and spill their contents outside the cell, where they bind to receptors on the postsynaptic neuron.

Most microbes conduct electron transactions deep in their own recesses, where the enzymes are; as a consequence, the organisms tend to seek out soluble electron receptors like oxygen that can slip inside the cell membrane, nab electrons, and slip out again.

It is clear, however, that volatile anesthetics, which are more soluble in lipids than in water, primarily affect the function of ion channel and neurotransmitter receptor proteins in the membranes of nerve cells, which are lipid environments.

When enough of the organisms gather together in a confined space, the compound becomes so concentrated that it permeates back through the cell membranes to combine with receptors inside the bacteria.

When attractant or repellant chemicals attach themselves to receptor sites on the surface membrane of a bacterium, it triggers a process within the cell that leads to the modification of the signal protein, CheY (pronounced «Key - Y»), enabling it to bind to the switch and change the bacteria's direction of movement.

Like all steroid hormones, estrogens readily diffuse across the cell membrane; inside the cell, they interact with estrogen receptors.

The mutation occurs in the gene ACVR1, and this gene produces a protein that is a receptor that spans the cell membrane — so part of the receptor is outside of the cell, and part is on the inside.

Cell - surface receptors are proteins embedded in the cell membrCell - surface receptors are proteins embedded in the cell membrcell membrane.

The «rotation model» Ligand binding to the extracellular part of the receptor induces rotation of the receptor's transmembrane region inside the cell membrane, and in doing so, regulates its activity inside the cell.

In the process, the plasma membrane receptor Fas (CD95) is key; this cell receptor occurs in almost all human cells and is involved in programmed cell death (apoptosis).

Hemaggluttinin's second job — after latching onto the host receptor — is to fuse viral and host cells» membranes once the virus enters the cell.

A receptor is a molecule placed on the cell membrane which, in some cases, can direct material from the surroundings to be taken up by the cell and degraded, In the degradation of bone tissue, the receptor uPARAP plays a central role.

More recently, the membrane receptor GARP was shown to bind to TGF - beta on regulatory T cells and platelets to modulate their activity.

In this latest study, the researchers placed an antibody with a weak radioactive component onto the receptors on the T - cells» outer membrane.

«This technique could be applied to other cell types of the immune system — anywhere the receptors on the membrane are renewed often,» says Griessinger.

Protection relies only on the IL - 6 receptors that are bound on macrophage cell membranes.

B cells that do not produce Caveolin - 1 can not properly organize the receptor on the cell membrane and as a result, efficient signal transfer fails.

«This longer receptor apparently means that the Cytolysin can connect with the receptor in wheat or barley, but can not reach the cell membrane — and therefore can not have its deadly effect,» Albert reports.

Intracellular interactions within the Golgi can lead to the formation of a complex between IL - 15 and IL - 15Rα, which can either be secreted or anchored to the cell membrane for trans - presentation to neighboring cells displaying IL - 2Rβ and γc receptors (21, 22).

The researchers describe «a finely tuned orchestration of three domain movements» that allows the receptors to elegantly control passageways across cell membranes.

Receptors are proteins that are usually located on the external surface of the cell membrane; they provide specific recognition sites for messenger substances such as hormones, neurotransmitters and growth factors.

Different conformations help serotonin receptors serve as «gatekeepers» in cell membranes.

Serotonin receptors sit in cell membranes throughout the body, including the brain, stomach, and nerves.

IL - 15 and IL - 15Rα interactions at the cell membrane can lead to recruitment of IL - 2Rβ and γc to form the heterotrimeric receptor, although IL - 15 signaling may not occur strictly as the result of a secreted cytokine binding to a cell surface receptor.

To examine the role of soluble antibodies in the accumulation of MDSCs, they included an additional model of CLL in which B cells can only produce membrane - bound antigen receptors but not soluble antibodies.