Sentences with phrase «cell memory generation»

Notably, the presence of ADA produced an increase in CD4 + responder T cells, in CD8 + T cell proliferation and in T cell memory generation.

Not exact matches

Associate Professor Palmer said that this next - generation test showed that HIV hides in the body's immune memory T - cells, which is how it avoids detection from the immune system.

However, little is known in humans about the biology of CD4 - CTL generation, their functional properties, and heterogeneity, especially in relation to other well - described CD4 + memory T cell subsets.

The study suggests that an optimal anti-tumor immune response requires the generation of both circulating and tissue - resident T cell memory.

The ultimate goal is to precisely understand the mechanisms of checkpoint blockade effectiveness and bring next generation, sustainable immunotherapies to even more patients, perhaps using by using epigenetic drugs in combination with checkpoint blockade to allow epigenetic reprogramming of exhausted T cells into durable and functional memory T cells.

The results show that generation of an optimal immune response to cancer requires cooperation between two types of memory T cell — one circulating in the blood and the other resident in tissues — that can be reactivated with current immunotherapy strategies.

Haploinsufficiency of Bach2 resulted in reduced generation of memory B cells, independently of suppression of the gene encoding the transcription factor Blimp - 1.

Additionally, we identified that combined deletion of DGKζ and Cbl - b resulted in similar impairment of antigen - specific memory CD8 + T cell generation and / or maintenance compared with KO.

This protein is involved in the generation of new brain cells and plays a role in learning and memory.

Led by scientists at UCLA, an international team of researchers has discovered that bacteria have a «memory» that passes sensory knowledge from one generation of cells to the next, all without a central nervous system or...

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