Sentences with phrase «cell memory secondary»
Prf1 − / − mice exhibit increased immunopathology with prior CD8 T cell memory secondary to immunization.
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When antigens such as viruses and vaccines enter the human body, germinal centers are produced within secondary lymph nodes and memory B cells are then induced from germinal - center B cells.
This is because memory B cells, which remember antigens in the primary immune response, are induced and respond faster in the secondary exposure to bacteria or viruses and differentiate into antibody - producing cells.
The phenotype of NP cells generated ex vivo (Figure S8) closely resembles that of central memory CD4 + T cells found in vivo, which persist for years in secondary lymphoid organs and can differentiate into effector memory CD4 + T cells [45].