Not exact matches
TOUGH STUFF A new wood - compacting process crushes the gaps between
cell walls in natural wood (porous structure seen in the scanning electron
microscopy image, left),
making the densified wood (right) as strong as steel.
By
making the switch, all molecules
made from fatty acids can be observed inside living
cells by an advanced imaging technique called stimulated Raman scattering (SRS)
microscopy.
Electron
microscopy revealed that the extra hair
cells were divided into inner and outer hair
cells, just like the normal ones, and they
made the same proteins.
Research problems that are just out of reach today but that could be
made accessible by advances in electron
microscopy include studies of the little pores that form in our
cells walls and which are centrally important in the regulation of all life processes as well as new nano - structured materials that are ultra-light yet strong, allowing reduced energy consumption in vehicles.
New techniques combining various staining methods with electron and light
microscopy make it possible to investigate in detail the connections among nerve
cells and the circuitry of the brain
The combination of two processes
makes this high - resolution 3D imaging possible: lattice light - sheet
microscopy (LLSM), which images one slice of the
cell at a time, and adaptive optics (AO), which corrects for any blurriness.
«Eggshells are notoriously difficult to study by traditional means, because they easily break when we try to
make a thin slice for imaging by electron
microscopy,» says McKee, who is also a professor in McGill's Department of Anatomy and
Cell Biology.
Researchers at Columbia University have
made a significant step toward breaking the so - called «color barrier» of light
microscopy for biological systems, allowing for much more comprehensive, system - wide labeling and imaging of a greater number of biomolecules in living
cells and tissues than is currently attainable.
Since it is still beyond the reach of even the most sophisticated in vitro methodology to simulate the complex interplay of physical, cellular, biochemical, and other factors that influence
cell behavior in microvessels and interstitial tissues, we
make use of intravital
microscopy.
Recent progress in phylogenomics, and the implementation of modern molecular,
microscopy, and
cell biology techniques in a handful of spiralian model systems have
made that possible.
In cases of neonatal mortality, the diagnosis typically is
made postmortem with virus isolation from fresh lung, liver, kidney, and spleen by
cell culture techniques and subsequent identification by PCR and sequencing, transmission electron
microscopy, immunofluorescence, or fluorescence in situ hybridization.