Sentences with phrase «cell migration»
Cell migration refers to the movement of cells from one place to another in the body. It happens when cells travel in a coordinated way to reach their intended destination. This process plays a vital role in various biological activities like wound healing, immune response, and embryonic development. Full definition
This will provide a major step forward in understanding cell migration in more physiological environments.
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The findings of the project also reveal how the same mechanisms of cell migration remain intact in the course of evolution, making it possible to draw comparisons between fish and humans.
Several labs are using the technology to study topics such as cell migration and neuroscience, he says.
It's the most abundant protein in most cells, and its different forms play roles during cell migration, muscle contraction and development.
Much of the research into tumor cell migration, however, has represented the tissue as a solid gel.
The phenomenon of collective cell migration has been observed in the process of animal development, the healing of wounds, and cancer cell invasion.
Control genes that can stimulate cell migration, thus helping inhibit breast cancer cells from moving to the bone and spreading the disease to other parts of the body.
It actively engages biologists working on distinct molecular mechanisms of cells migration and helps them interact beyond the boundaries of independent laboratories.
We know phytates inhibit cancer cell migration in vitro, and now, perhaps, we know why.
«These findings demonstrate that efficient actin filament disassembly by GMF is essential for rapid dynamics of cell protrusions, and that this dynamics are important for cell migration in a three - dimensional tissue environment,» says Minna Poukkula from the research group of professor Pekka Lappalainen.
«Our findings show for the first time that (the enzyme) regulates endothelial filopodia formation and, most importantly, endothelial cell migration by rearranging the cells» phospholipid composition,» the authors report.
To see if the same chain of events happens in rheumatoid arthritis, Smith's team tested whether various kinds of fibroblasts would spur T cell migration in test tubes.
The presence or absence of endoderm does not affect lateral mesodermal cell migration in wild - type and toddler mutants.
We describe here a further function for this ligand - receptor pair in promoting cell migration into the SCS.
The laboratory is working in collaboration with Dr. Paula Foster to develop real - time cellular magnetic resonance imaging techniques as a means to track dendritic cell migration in vivo in humans.
The entire intestinal epithelium is renewed every week due to cell division in the crypts coupled with cell migration towards the villi and loss of cells by apoptosis at the tip of villi (Fig. 1A).
But other lipids are known to guide cell migrations in human brain development, and geneticist Ken Howard of University College London suspects HMG - CoA reductase might help produce a similar lipid molecule or modify a protein that attracts the germ cells.
The treatment can also easily kill cancer cells, but in this experiment, it was vital to specifically show that it virtually halts cell migration.
«New mechanism affecting cell migration found.»
A team of researchers at the Massachusetts General Hospital and Harvard Medical School in Boston has developed technologies for precision measurement of cell migration speed before and applied the new tool to study the variations of migration speed in population of cancer cells.
Delineating the core regulatory elements crucial for directed cell migration by examining folic - acid - mediated responses.
Conversely, endodermal cell migration defects are dependent on a Cxcr4a - regulated tether to mesoderm».
«New regulatory mechanisms of cell migration found in drosphilia fly study.»
Adding two blood - borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.
We use gut as model system to study cell migration in homeostasis, wound healing and cancer invasion (Fig. 1).
They also control cell migration and organization.
The researchers also report that saliva increased DENV infection of immune cells in the skin and enhanced immune cell migration to neighboring lymph nodes, which could promote the spread of disease throughout the body.
On the role of PDZ domain - encoding genes in Drosophila border cell migration.
When they neutralized the biglycan receptors with antibodies, tumour cell migration toward the endothelium was inhibited.
IGFBP5 induces cell adhesion, increases cell survival and inhibits cell migration in MCF - 7 human breast cancer cells.
Mathematician Dr John MacKenzie and molecular biologist Professor Robert Insall have teamed up to take a novel approach to understanding cell migration.
Panretinal donor cell migration also affords better access to Müller glia, which bind and mediate host responses to some neurotrophic factors, including GDNF [26].
The «specification model» postulates that Toddler signaling enhances Nodal signaling to properly specify endoderm, whereas the «migration model» posits that Toddler signaling regulates mesendodermal cell migration downstream of Nodal signaling.
As a postdoctoral fellow at the University of Washington she developed a method to image and track cell migration in live zebrafish embryonic tissue explants.
During time - lapse imaging, the tracking function enables users to measure and analyze cell migration and division as well as luminosity.
When those cells were placed on a standard wound assay (for measuring properties like cell migration and proliferation), they moved unusually fast.
The phase of gastrulation, in which the germ layers form through invagination of the outermost cell layer, is the first great cell migration phase in the development of vertebrates.
Finally, the study showed that RORα regulates the expression of several genes important for Treg cell migration and function; those pathways could be potential targets too.
Analysis of cat DNA found that house cats and wild cats have different versions of genes implicated in neural crest cell migration (SN: 12/13/14, p. 7).
The treatment did a lot to prevent cell migration, a key mechanism in metastasis, in experiments on laboratory cultures (in vitro) of cancerous human cells.
Fu plans to further explore the link between PLK1 and MAPK signaling in prostate cancer patients and determine whether PLK1 - induced EMT contributes to other cancer - promoting processes that go beyond cell migration and metastasis.
The research group has found that this technology allows scientists to inactivate critical biological phenomena, including cell migration and cell division, by using only lights, and without the assistance of chemical drug treatments or genetic modification.