Sentences with phrase «cell migration in»

The presence or absence of endoderm does not affect lateral mesodermal cell migration in wild - type and toddler mutants.

Intranodal T - cell migration in Enpp2fl / fl mice and Ccl19 - Cre Enpp2fl / fl mice, analyzed by intravital two - photon microscopy.

These observations indicate that the reduced mesodermal cell migration in toddler mutants limits endodermal dispersion and that Toddler signaling is not required for endodermal cell migration per se.

Cell migration in wound healing assays is a popular application using microplate readers.

Cell migration in gut homeostasis and wound healing.

We use gut as model system to study cell migration in homeostasis, wound healing and cancer invasion (Fig. 1).

Scientists have released video showing immune cell migration in the Zebrafish inner ear.

100 uM dideoxystreptamine - based drug inhibits colon cancer cell migration in the high - throughput Platypus fluorescent assay

N - cadherin - mediated cell — cell adhesion promotes cell migration in a three - dimensional matrix.

Dekaban, G.A. *, Snir, J., Shrum, B., de Chickera, S., Willert, C., Said E.A., Sékaly, R.P., Foster, P.J. and O'Connell, P.J. * Semi-quantitation of mouse dendritic cell migration in vivo using cellular MRI.

IGFBP5 induces cell adhesion, increases cell survival and inhibits cell migration in MCF - 7 human breast cancer cells.

The laboratory is working in collaboration with Dr. Paula Foster to develop real - time cellular magnetic resonance imaging techniques as a means to track dendritic cell migration in vivo in humans.

The small GTPase Rac is a key factor known to be involved in phagocytosis and cell migration in mammals and has been shown to be essential for hemocyte migration within the embryo [29], [30].

In addition, cells were stimulated with a growth factor (PDGF) which led to fast cell migration in only one direction lasting for many hours.

By using fruit fly as a model system, Minna Poukkula working at the Institute of Biotechnology, University of Helsinki, has found out how actin - rich protrusions contribute to cell migration in animal tissues.

«These findings demonstrate that efficient actin filament disassembly by GMF is essential for rapid dynamics of cell protrusions, and that this dynamics are important for cell migration in a three - dimensional tissue environment,» says Minna Poukkula from the research group of professor Pekka Lappalainen.

To see if the same chain of events happens in rheumatoid arthritis, Smith's team tested whether various kinds of fibroblasts would spur T cell migration in test tubes.

The scientists hope their findings on cell migration in zebrafish will open up new perspectives for research on proteins that control metastasis and thus the malignancy of cancer.

But other lipids are known to guide cell migrations in human brain development, and geneticist Ken Howard of University College London suspects HMG - CoA reductase might help produce a similar lipid molecule or modify a protein that attracts the germ cells.

Although originally studied primarily in two - dimensional in vitro assays, most cell migrations in vivo occur in complex three - dimensional tissue environments that are difficult to recapitulate in cell culture or ex vivo Further, it is now known that cells can mobilize a diverse repertoire of migration modes and subcellular structures to move through and around tissues.

Not exact matches

In the article, Dr. Margot Sunderland, author of the best - selling book What Every Parent Needs To Know, stated that leaving a child in a state of distress for a prolonged period without offering comfort affects them on a cellular level, specifically the «migration» of their cells as they get to where they need to bIn the article, Dr. Margot Sunderland, author of the best - selling book What Every Parent Needs To Know, stated that leaving a child in a state of distress for a prolonged period without offering comfort affects them on a cellular level, specifically the «migration» of their cells as they get to where they need to bin a state of distress for a prolonged period without offering comfort affects them on a cellular level, specifically the «migration» of their cells as they get to where they need to be.

The researchers also report that saliva increased DENV infection of immune cells in the skin and enhanced immune cell migration to neighboring lymph nodes, which could promote the spread of disease throughout the body.

But when their functioning is altered, as the UCL researchers observed in tumor cells, the mitochondria can promote cell migration, thus leading to the formation of metastasis.

Groups of red and green labelled embryonic cells in a zebrafish during their first migration in gastrulation.

Furthermore, they found that by inhibiting Akt they could significantly slow cell proliferation, cell migration and cell invasion in the lung cancer and bladder cancer cells.

The phase of gastrulation, in which the germ layers form through invagination of the outermost cell layer, is the first great cell migration phase in the development of vertebrates.

Adding two blood - borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.

Using a mouse model, the team also demonstrated that two processes during neurodevelopment are regulated by the gene: proliferation — the replication of neuronal stem cells that have the potential to become multiple different kinds of cells, including neurons — and migration — the movement of neurons to specific locations in the brain during development.

This study, published in the journal Microarrays, shows that lack of SOST in the bone microenvironment promotes the expression of many genes associated with cell migration and / or invasion, including long non-coding RNA MALAT1 in prostate cancer, suggesting that SOST has an inhibitory effect on prostate cancer invasion.

Changes in the cells» migration might account for many physical traits linked to tameness in domesticated animals.

The inside back cover image of the Nov. 20, 2017 issue of Advanced Materials illustrates how ion migration in a hybrid perovskite crystal affects solar cell performance in different areas of the crystal.

Consistent with previous findings, Apc suppression in the animals activated the Wnt signaling pathway, which is known to control cell proliferation, migration, and survival.

The T cell migration halted again when the team added a chemical that blocks the IGF - 1 receptor, the authors report 23 August in the Journal of Immunology.

In a new study, NAIST scientists, in collaboration with researchers at the Osaka National Hospital and University of Tokyo, report that the L1 Cell Adhesion Molecule (L1 - CAM) is crucial for directed axon migratioIn a new study, NAIST scientists, in collaboration with researchers at the Osaka National Hospital and University of Tokyo, report that the L1 Cell Adhesion Molecule (L1 - CAM) is crucial for directed axon migratioin collaboration with researchers at the Osaka National Hospital and University of Tokyo, report that the L1 Cell Adhesion Molecule (L1 - CAM) is crucial for directed axon migration.

The research team tested the cells in dishes that were treated with luteolin and found that migration was inhibited by the plant compound.

New research shows that microRNA - 486 is a potent tumor - suppressor molecule in lung cancer, and that the it helps regulate the proliferation and migration of lung - cancer cells, and the induction of programmed cell death, or apoptosis, in those cells.

The team also found five genes in domestic cats that influence the migration of neural crest cells, stem cells in the developing embryo that affect everything from skull shape to coat color.

Named after the enigmatic sphinx, this cell signal is important in many activities of living cells, from migration to proliferation.

To test this idea, they experimentally reduced the expression of the DNM30S lncRNA, which resulted in reduced ovarian cancer cell migration and invasion.

«In normal conditions, the microenvironment is able to control the proliferation, differentiation and migration of the hematopoietic stem cell.

By decreasing the expression of CerS4 in these mice, the Ogretmen laboratory hopes to better define the way in which CerS4 regulates cell migration and metastasis.

More importantly, the fibronectin part of the complex is expressed during a cell's transition to cancer and plays a role in cell growth, migration and differentiation.

The treatment can also easily kill cancer cells, but in this experiment, it was vital to specifically show that it virtually halts cell migration.

The researchers found that PAI - 039 inhibited the migration of cultured human coronary artery smooth muscle cells, and prevented the development of blockages in arteries and bypass grafts in mice.

A group of researchers led by Kosuke Fujita, Visiting Researcher and Akito Maeda, Specially Appointed Professor at the HP Skin Regeneration, PIAS Collaborative Research, Osaka University clarified that cinnamtannin B - 1, or vegetable - based polyphenol, promotes the migration of Mesenchymal Stem Cells (MSCs) in blood circulation and accumulates them in damaged tissues (Fig. 1) to improve wound healing.

The treatment did a lot to prevent cell migration, a key mechanism in metastasis, in experiments on laboratory cultures (in vitro) of cancerous human cells.

SUSHI also visualizes synaptic clefts for the first time in slices of live tissue and reveals glia - neuron interactions and cell migration.

Fu plans to further explore the link between PLK1 and MAPK signaling in prostate cancer patients and determine whether PLK1 - induced EMT contributes to other cancer - promoting processes that go beyond cell migration and metastasis.

Recently published in the journal eLife and featured in a poster session at this year's American Association for Cancer Research (AACR) annual meeting, preclinical experiments show for the first time that PLK1 promotes the migration of prostate cancer cells by setting in motion a process that induces what is known as the epithelial - to - mesenchymal transition (EMT).

Researchers have uncovered a sieve - like structure in lymph nodes that regulates the transport of proteins and migration of white blood cells into lymph nodes.