Sentences with phrase «cell mitosis»

16α - OH E1, also a Phase I estrone metabolite, is an estrogen agonist, stimulates cell mitosis and proliferation, and is associated with increased risk of prostate cancer.

Jan Ellenberg, EMBL Germany, showed films from his lab showing cell mitosis in high resolution.

I'd bet that 90 % of those who know enough basic biology to write a short essay on cell mitosis and DNA replication would also say «evolution is obvious and is the basis for of all of modern biology».

Not exact matches

Single - celled organisms reproduce by mitosis, whereas multi-cellular organisms reproduce by meiosis, using specialised sex cells, the germ line.

(Sex is not reproductive, he says, but rather a reduction of two gamete cells into one — it's mitosis, the duplication of cells, that is reproductive.

«Because most transcription largely ceases in mitosis, and many proteins dissociate from the chromosome, something has to be responsible for reassembling chromosomes after cell division according to their cell type.

During mitosis, microtubules disassemble and reform into spindles that are used by the dividing cell to move chromosomes.

Microtubules, hollow fibers of tubulin protein only a few nanometers in diameter, form the cytoskeletons of living cells and play a crucial role in cell division (mitosis) through their ability to undergo rapid growth and shrinkage, a property called «dynamic instability.»

Like others before him, Schrödinger was struck by the fact that chromosomes are accurately duplicated during ordinary cell division (mitosis, the way in which an organism grows) and during the creation of the sex cells (meiosis).

Broadly, most chemotherapeutic drugs work by impairing mitosis (cell division), effectively targeting fast - dividing cells.

This is the first demonstration of TBK1 regulating mitosis and cell cycle progression.

After the parental cell DNA is replicated, the duplicated DNA and cellular organelles are separated into two daughter cells during mitosis.

When they disrupted TBK1 activity, the cells could not separate chromosomes correctly into daughter cells and mitosis could not progress.

Moffitt Cancer Center researchers have found that a protein called TBK1 plays an important role in the process of cell division, especially at a stage called mitosis.

Disruption of TBK1 interactions with either CEP170 or NuMA resulted in defects in mitosis and prevented cell division.

Paradoxically, the exception is at the very moment when chromosomes are most vulnerable, when they physically separate into two cells at cell division (mitosis).

«Cells do not repair damage to DNA during mitosis because telomeres could fuse together.»

This revealed telomeres as dangerous structures during mitosis, because the cells momentarily lost the ability to distinguish between damaged DNA strands and normal telomeres.

Proteins called kinesins, for example, are natural nanomotors that support cellular functions such as mitosis (the chromosomal process that creates two nuclei from one parent nucleus) and meiosis (when the number of chromosomes per cell is reduced by one half).

Mitosis, the cellular division that produces two genetically identical daughter cells, is perhaps the most fundamental process in biology.

As all school - children learn, cells divide using a process called mitosis, which consists of a number of phases during which duplicate copies of the cell's DNA - containing chromosomes are separated into two distinct cells.

«We challenged a current dogma in the field that emphasized PLK1's role in mitosis (cell division) as a primary mechanism for cancer growth,» says Zheng Fu, Ph.D., lead investigator on the study, member of the Cancer Molecular Genetics research program at VCU Massey Cancer Center and assistant professor in the Department of Human and Molecular Genetics at the VCU School of Medicine.

«A way to stabilize haploidy in animal cells: Mammalian haploid cells present problems during mitosis that limit their viability; the removal of the p53 tumor suppressor gene increases the survival rate of these cells thereby stabilising their haploid state.»

In the process of mitosis each cell is apportioned a complete set of hereditary instructions when the chromosomes replicate and are separated by the mitotic apparatus

Their studies show that the problem arises when the haploid cells try to separate their chromosomes during mitosis.

Evidently they were simple phytoplankton that reproduced by asexual body cell division (mitosis).

In particular, consumption of whole plant foods slows digestion and provides higher amounts and a more favourable balance of essential and vital nutrients per unit of energy; resulting in better management of cell growth, maintenance, and mitosis (cell division) as well as regulation of blood glucose and appetite.

Kiyomitsu's latest work focuses on the next step of mitosis, called anaphase, when the microtubules tear the paired chromosomes apart so that one copy of each chromosome ends up in each of the new daughter cells.

Until now, however, none has actually seen how human cells manage to divide into two equally - sized daughter cells during mitosis.

«It's now understood to be absolutely essential for mitosis in virtually all eukaryotic cells,» Scholey said.

The scientists looked at a process known as meiosis, which unlike normal cell division (mitosis) has two rounds of nuclear division, to ensure that when sex cells fuse with each other, they have two copies of each chromosome — one from each parent!

The team used ChromEMT to image and measure chromatin in resting human cells and during cell division (mitosis) when DNA is compacted into its most dense form — the 23 pairs of mitotic chromosomes that are the iconic image of the human genome.

But when a cell prepares to undergo mitosis — a type of cell division — those strings of DNA must condense into easy - to - transfer cylinders.

We hypothesize that unisexual reproduction is a hypermutagenic process that generates genetic diversity de novo and that the resulting progeny can thereby more rapidly adapt to changing environments than cells produced asexually by mitosis.

Decreased adherence and increased stiffness of cells overexpressing centrosomal ninein ‐ like protein causes dissemination of wild ‐ type cells undergoing mitosis from mosaic epithelia.

Aurora kinases are enzymes that control mitosis, the process of cell division, and were first discovered in the 1990s in yeast, flies and frogs.

Figure 1: FGFR - TACC fusion protein disrupts cellular division (mitosis) by localizing aberrantly at the mid-body of dividing cells.

Identification of proteins that bind and control microtubule nucleation and dynamics during mitosis (Vernos group, Current Biology 2012, 2013, Nature Comm 2014, 2015, Current Biology 2015, J Cell Sci 2016, Mol Biol Cell 2016).

In the center, FGFR - TACC fusion protein (red) can be seen disrupting tubulin bundles (green), structures that support cell division, or mitosis, at the point connecting the two daughter cells (whose nuclei are colored blue).

Leucine carboxyl methyltransferase - 1 is necessary for normal progression through mitosis in mammalian cells.

Here, FGFR - TACC (shown in red) can be seen interacting with tubulin bundles (green), structures that support mitosis, at the point connecting the two daughter cells (whose nuclei are colored blue).

The researchers discovered that the protein produced by FGFR - TACC acts by disrupting the mitotic spindle, the cellular structure that guides mitosis (the division of a cell into two identical daughter cells).

While retroviruses generally only infect dividing cells (because their access to the host genome is thought to rely on the breakdown of the nuclear envelope that occurs in mitosis [Roe et al., 1993]-RRB-, lentiviruses are a genus of the retroviral family that can infect non-dividing cells (possibly through the use of nuclear localization signals by the viral components [Bukrinsky et al., 1992]-RRB-, and thus, offer an advantage when transducing certain cell types that exhibit limited cell division (e.g., neurons).

Redistribution of Golgi stacks and other organelles during mitosis and cytokinesis in plant cells.

Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis.

Heritable genetic variation is the result of genome instability during germ cell development, instability that arises through mutation, chromosome rearrangement or chromosome mis - segregation during mitosis or meiosis.

Increasing β - catenin / Wnt3A activity levels drive mechanical strain - induced cell cycle progression through mitosis.

Shorter patient survival was generally associated with up - regulation of genes involved in mitosis and cell growth, and down - regulation of genes involved in cellular differentiation.

Upon expression in dividing cells, survivin is rapidly recruited to various aspects of the mitotic apparatus, the scaffolding of microtubules that serve to physically separate and sort the proper complement of chromosomes into each of the two new cells that result from mitosis.

Cells produce — or «express» — great quantities of survivin just before they undergo the process of cell division, also called mitosis.