Author: Russ Brown and Cameron Hutchison are law professors at the University of Alberta, and Ubaka Ogbogu is research associate / project manager - stem
cell network at the University of Alberta's Health Law Institute.
Not exact matches
The balloons themselves are essentially a
network of solar - powered, airborne
cell towers floating
at a height between 60,000 to 90,000 feet, or roughly twice as high as planes fly.
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Carlo Croce, a cancer researcher
at Ohio State University in Columbus, and his colleagues created a diagram of interacting miRNAs for normal body
cells by connecting them according to which genes they target and the function of those genes, in a way similar to analyses of human social
networks.
«What we can see is that space - time
at the quantum - scale might be
networked in a very similar way to things we are starting to understand very well like biological
networks in
cells, our brains and online social
networks.»
«Our findings provide a possible flanking strategy to counteract the ability of melanoma
cells to re-wire their signaling
networks,» said co-coresponding author Meenhard Herlyn, Caspar Wistar Professor in Melanoma Research and director of the Melanoma Research Center
at The Wistar Institute.
The findings — published today in Nature — provide significant insights into
cell types fated to relapse and can help accelerate the quest for new, upfront therapies, says Dr. Dick, a Senior Scientist
at Princess Margaret Cancer Centre, University Health
Network, and Professor in the Department of Molecular Genetics, University of Toronto.
Chien Ho, professor of biological sciences
at Carnegie Mellon University, and his colleagues have developed a novel way to improve delivery of chemotherapy nanodrugs by using Intralipid ®, an FDA - approved nutrition source to temporarily blunt the reticuloendothelial system — a
network of
cells and tissues found throughout the body, including in the blood, lymph nodes, spleen and liver, that play an important role in the immune system.
My cancer systems biology team
at the University of California, Merced, is tackling diagnosis and treatment of therapy - resistant cancers by elucidating the
network of changes within
cells as a way to identify new drug targets and circumvent cancer resistance.
Physicians now have robust data to help them counsel patients and make informed decisions regarding treatment options,» says study co-author Lloyd P. Aiello, M.D., Ph.D., Professor of Ophthalmology
at Harvard Medical School, Director of Joslin's Beetham Eye Institute, co-head of Joslin's Section of Vascular
Cell Biology, and founding chair of the DRCR
Network.
► This afternoon, Normile reported
at ScienceInsider that top administrator's
at RIKEN, Japan's
network of laboratories, «will voluntarily return 1 to 3 months of their salaries to atone for their responsibility for the STAP stem
cell fiasco.»
«If you look
at a normal tissue,» Shenoy said, «you see the
cells are more rounded, and the
network of ECM fibers is more random.
When The Cancer Genome Atlas Research
Network reported its genomic profiling of clear -
cell kidney tumours, about one - quarter of participants (126 patients) had been operated on
at Memorial Sloan Kettering3.
«This calls for a systems level approach, and
network analysis techniques, to really understand how normal
cells are transformed into cancer
cells at the molecular level.»
Plant researchers
at VIB and Ghent University have now identified a new molecular
network that increases our understanding of stem
cell regulation and activity.
His research group focuses on big data
network biology, exploring biological systems by developing and deploying algorithms aimed to predict
cell behavior, in particular looking
at cellular signal processing and decision making.
The team from the cluster of excellence BrainLinks - BrainTools and the Bernstein Center
at the University of Freiburg and the UNIC department of the French Centre national de la recherche scientifique in Gif - sur - Yvette created a computer model of
networks of nerve
cells and analyzed its properties for signal propagation.
A good idea can be like that — it stirs everything up — whether it is being shared throughout a
network of
cells in one person's brain or in the world
at large, through a community of people.
A strategic focus is to continue to develop computational tools (such as KinomeXplorer, NetworKIN, and NetPhorest) and to deploy these on genome - scale quantitative data obtained by, for example, mass spectrometry, genomic, and phenotypic screens to understand the principles of how spatio and temporal assembly of mammalian signaling
networks transmit and process information
at a systems level in order to alter
cell behavior.
Microprocessors modeled on
networks of nerve
cells promise blazing speed
at incredibly low power — if they live up to hopes.
The findings, featured on the cover of the March 7 issue of
Cell Reports, show that patients with high levels of the biomarker, CD151, have a poor prognosis, says lead author Mauricio Medrano, a molecular biologist and research associate
at Princess Margaret Cancer Centre, University Health
Network.
«We're looking
at the genes and gene
networks involved in stem
cell proliferation, meristem development and flowering and branching,» said Van Eck, «with the end goal being that maybe genes that we identify in tomato, which is strictly being used as a model, might help us understand what can be done to increase yield in other crops.»
Biologists had already observed this interaction in living systems — a coral reef whose millions of tightly
networked members could communicate data about weather over hundreds of miles and a slime mold whose millions of member
cells, spread out over acres, could coalesce and take organized action for survival
at a moment's notice.
Webster then left the company for a position
at Duke University where he was the library management
network guru, and building upon his experience there, he eventually landed his latest position with «Skip» Bollenbacher's
CELL group
at the University of North Carolina, Chapel Hill, last September.
When the researchers looked
at activity
at the cellular level in the rats» brains, they saw that individual
cells stimulated by the optogenetics would increase firing rates in the PER
network and that many
cells fired in sync with the optical flicker frequency.
«We have revealed novel components and connections in the regulatory
network underlying how these T
cells mount an immune response,» said study co-leader Kai Tan, PhD, of the Center for Childhood Cancer Research and the Departments of Pediatrics and Biomedical and Health Informatics
at CHOP.
«Using the genome data analysis methods developed by co-author Steve Horvath
at UCLA, we have uncovered crucial gene
networks and we can now predict possible future genetic disorders
at the eight -
cell stage.»
Solving a puzzle of plant manipulation Rather than try to isolate single genes related to secondary
cell wall production, the researchers looked
at the function of hundreds of transcription factors working within the root xylem's regulatory
network.
Specifically, the study revealed parallels to autism in humans
at the levels of brain
cells,
networks, and behavior, said study senior author Carlos Aizenman, associate professor of neuroscience
at Brown.
«It really hasn't been explored when these activity
networks — these collections of brain areas that start to work together in the brain — emerge and what types of
cells and tissues they emerge in,» says Colin Studholme, Ph.D., a professor with joint appointments in pediatrics and bioengineering
at the University of Washington and senior author of the paper.
The research group working
at IBMC focused on the exact moment of
cell division, when
cells assemble a new microtubule
network, which is then arranged as a very well - known structure: the mitotic spindle.
Every
cell in our bodies contains a railway network, a system of tiny tracks called microtubules that run between important destinations inside the cell and allow cargo to be carried from one place to another, reports Professor Rob Cross, Professor of Mechanochemical Cell Biology at Warwick Medical Sch
cell in our bodies contains a railway
network, a system of tiny tracks called microtubules that run between important destinations inside the
cell and allow cargo to be carried from one place to another, reports Professor Rob Cross, Professor of Mechanochemical Cell Biology at Warwick Medical Sch
cell and allow cargo to be carried from one place to another, reports Professor Rob Cross, Professor of Mechanochemical
Cell Biology at Warwick Medical Sch
Cell Biology
at Warwick Medical School.
Professor Rob Cross, Professor of Mechanochemical
Cell Biology at Warwick Medical School, said: «Every cell in our bodies contains a railway network, a system of tiny tracks called microtubules that run between important destinations inside the cell and allow cargo to be carried from one place to anot
Cell Biology
at Warwick Medical School, said: «Every
cell in our bodies contains a railway network, a system of tiny tracks called microtubules that run between important destinations inside the cell and allow cargo to be carried from one place to anot
cell in our bodies contains a railway
network, a system of tiny tracks called microtubules that run between important destinations inside the
cell and allow cargo to be carried from one place to anot
cell and allow cargo to be carried from one place to another.
If the work proceeds as expected, «all interactions between genes, proteins, and small molecules will be revealed, and the whole cellular
network will be reconstructed,» says Igor Goryanin, who heads
cell modeling
at GlaxoSmithKline in Stevenage, U.K.
«Interest in the role of ER - Golgi
network during cancer
cell death has been gaining momentum,» said Shanshan He, Ph.D., research associate
at the Keck School of Medicine of USC and one of the study's first authors.
This better understanding of how the
network functions could allow scientists to engineer new types of
cells, says Hiroshi Tanaka, a bioinformaticist
at Tokyo Medical and Dental University.
Moreover, it is all - software - configurable in that it can change
at the flip of a bit (in any country) from a
cell phone to a two - way radio talking to other Handy 21s, to a
network node near a high - speed wireless office
network, or to a plain FM radio.
Researchers
at the Mechanobiology Institute have comprehensively described the
network of proteins involved in
cell -
cell adhesions, or the cadherin interactome.
-- To better understand how and why these specialized sub
networks are created, researchers
at the Max Planck Florida Institute for Neuroscience (MPFI) have combined electrophysiological and optical approaches to manipulate and monitor neuronal activity
at single -
cell resolution in intact, functional brain circuits.
«We trained the neural
network by showing it two sets of matching images of the same
cells; one unlabeled and one with fluorescent labels,» explained Christiansen, software engineer
at Google Accelerated Science.
«We see elements of this framework of primary and secondary
cell - fate determinants throughout the hematopoietic system,» said study author Harinder Singh, the Louis Block Professor of Molecular Genetics & Cell Biology and a Howard Hughes Medical Institute Investigator at the University of Chicago, «and we suspect such networks also regulate cell fate in other systems.&ra
cell - fate determinants throughout the hematopoietic system,» said study author Harinder Singh, the Louis Block Professor of Molecular Genetics &
Cell Biology and a Howard Hughes Medical Institute Investigator at the University of Chicago, «and we suspect such networks also regulate cell fate in other systems.&ra
Cell Biology and a Howard Hughes Medical Institute Investigator
at the University of Chicago, «and we suspect such
networks also regulate
cell fate in other systems.&ra
cell fate in other systems.»
«We trained the neural
network by showing it two sets of matching images of the same
cells; one unlabeled and one with fluorescent labels,» coauthor Eric Christiansen, a software engineer
at Google Accelerated Science, says a press release.
Results: Scientists
at Pacific Northwest National Laboratory have developed a new computational approach for comparing receptor
networks in
cells.
The following article has been crafted from the comments of those speaking
at this discussion: Timothy Caulfield, LL.M., Health Law Science Policy Group, University of Alberta, Ira Herrmann, Stem
Cell Network NRW, Düsseldorf, Dan Kaufman, M.D., Ph.D., University of Minnesota, Megan Munsie, Ph.D., Stem
Cells Australia and, Jeremy Sugarman, M.D., M.P.H., M.A., John Hopkins Berman Institute of Bioethics.
We aim
at understanding (1) the regulatory properties emerging from and the constrains imposed by the modular and dynamic organisation of the
network; (2) the epigenetic mechanisms ensuring the rapid reestablishment of the
network after each
cell division and, conversely, those promoting its dismantling upon differentiation; (3) the contribution of non-coding RNAs to the regulation of the
network's activity.
Now researchers
at UC San Francisco have taken the first step toward a comprehensive atlas of gene expression in
cells across the developing human brain, making available new insights into how specific
cells and gene
networks contribute to building this most complex of organs, and serving as a resource for researchers around the world to study the interplay between these genetic programs and neurodevelopmental disorders such as autism, intellectual disability and schizophrenia.
At any given instant it can be argued that the
cell is in a «state» defined by its components — their concentrations and locations, the interactions between components — that are modulated in space and time, and the complex circuitry — that involves a large number of interacting
networks and a snapshot of the dynamical processes — such as gene expression,
cell cycle, transport of components, etc..
We would like to thank Dr. Elke Küster - Schöck and the
Cell Imaging and Analysis
Network Center
at the McGill Biology Department for their help with super-resolution microscopy.
The goal of this work is to characterize the role of dendrites in learning and memory processes so as to formulate a unifying theory regarding their contribution in memory formation across brain regions and abstraction levels.This will be achieved via the development of computational models that start
at the single
cell level and expand to the microcircuit and the
network level, while varying in their degree of biophysical detail.