Not exact matches
The
cell nuclei become fragmented, and some
cells will even
undergo apoptosis — auto - induced
cell suicide.
To overcome the problem of visualizing chromatin in an intact
nucleus, O'Shea's team screened a number of candidate dyes, eventually finding one that could be precisely manipulated with light to
undergo a complex series of chemical reactions that would essentially «paint» the surface of DNA with a metal so that its local structure and 3D polymer organization could be imaged in a living
cell.
In 1938, Hans Spemann showed that a
nucleus from a fertilized salamander egg that had already
undergone cell division several times could be implanted into a
cell from a newly fertilized salamander egg that is enucleated (has had its
nucleus removed) and create an entire adult salamander (Spemann, 1938).