Sentences with phrase «cell nucleus receptor»
The team led by John Hogenesch, PhD, a professor of Systems Pharmacology and Translational Therapeutics in the Perelman School of Medicine at University of Pennsylvania and Jason DeBruyne, PhD, a former postdoctoral fellow in the Hogenesch lab and now an assistant professor at Morehouse School of Medicine in Atlanta, applied their new method to identifying other clock partners that target a multipurpose cell nucleus receptor for disposal.
https://www.sciencedaily.com/ Not exact matches
The red cells are muscle cells, the green areas are receptors for neuronal input, and the blue patches are cell nuclei.
These receptors, called receptor tyrosine kinases (RTKs), transmit instructions through the cell wall and down through a cascade of reactions to a target gene in the nucleus.
They work by binding to receptors inside a cell, which then travel to the nucleus and act on the DNA by turning select genes on and off.
In addition, others (36) have shown that inhibition of exportin 1, a nuclear export receptor, can lead to accumulation of p70S6K in the nucleus of kidney cells.
The researchers found that when they dosed cells that expressed a2C - AR with chemicals that activate Rap1A, either directly or through means that involve another protein called Epac, the cells drew from pools of a2C - AR near the cell's nucleus and moved these receptors to the cell surface.
Calcitriol mediates its biological effects by binding to the vitamin D receptor (VDR), which is principally located in the nuclei of target cells.
The hormone enters the cell, attached to a receptor, and then enters the nucleus of the cell where it binds directly to the DNA.
Once this happens, the receptor enters the nucleus of its cell and attaches to specific spots on the chromosomes that contain all of the cell's genetic coding.