Sentences with phrase «cell omics»
Recent advances in single - cell omics and other techniques are revealing variation at genomic, epigenomic, transcriptomic, and posttranscriptomic levels.
https://www.the-scientist.com/ Not exact matches
A team of multidisciplinary researchers with expertise spanning biotechnology, information technology, and medicine have used a combination of several «omics technologies to map proteins down to the single cell level, showing both proteins restricted to certain tissues — such as the brain, heart, or liver — and those present in all tissues.
He is now a postdoctoral scholar in the Division of Biology and Biological Engineering at Caltech, working with Lior Pachter on statistics for omics based cell biology.
These questions will be addressed by combining unbiased «omics» - approaches (i.e. genomics, transcriptomics, and proteomics) and a targeted genetic analysis with both superresolution live - cell imaging and electron microscopy of nanotube - forming cells.
Omics experiments used to require tens of thousands of cells.
Omics techniques employed in our group range from whole genome sequencing and epigenomic techniques, to single cell / single strand DNA sequencing (Strand - seq; see Figure 1), the latter of which enables haplotype - resolved studies of genetic variation and genome instability.
The Dotiwala laboratory uses cellular, molecular, biochemical and omics approaches, as well as sophisticated in vivo imaging, to dissect the mechanism by which cell - based immunity (neutrophils, macrophages and killer lymphocytes) is activated in the presence of different pathogenic bacteria, such as intra - and extracellular bacteria, fungi and protozoa.
Our paper titled An integrated systems genetics and omics toolkit to probe gene function is published online in Cell Systems.
Dr. Lanteri now serves as Director Scientific Affairs at Cerus Corporation while remaining an Affiliate Investigator at BSRI, participating in ongoing research with the REDS - III group of investigators on: i) Zika virus persistence using samples collected longitudinally from ZIKV - infected donors and ii) the red blood cell storage lesion through the RBC - Omics project.
Aim 3: We are specifically interested how defects of nuclear proteins cause axonal phenotypes using live cell imaging techniques, inhibitor studies, laser irradiation, - omics approaches.
This is ideal for functional validation of discoveries / hits from large - scale omics projects in human cells.
Additional «- omics» data streams include: transcriptomics, the pattern of RNA synthesis from DNA; proteomics, the distribution of proteins in cells; interactomics, the patterns of protein - protein and protein — nucleic acid interactions; and metabolomics, the nature and traffic patterns of transformations of small molecules by the biochemical pathways active in cells.