The phrase
"cell phenotype" refers to the physical characteristics or traits exhibited by a cell. It describes what a cell looks like and how it behaves, including its shape, size, structure, and functions.
Full definition
1) Notch - 1 induces epithelial — mesenchymal transition consistent with cancer stem
cell phenotype in pancreatic cancer cells:
Furthermore, despite growing circumstantial evidence that pericytes might be the in vivo native counterparts of the ex vivo MSCs, there has been no direct evidence (by prospective cell lineage tracking experiments) that pericytes display key features of stem cells including proliferation and differentiation into
mature cell phenotypes in vivo following injury.
Learn about the latest approaches to assessing cancer - immune interactions («immune profiling») using FFPE tissue sections, multiplexed immunofluorescence, and cell phenotyping software
Neonatal Inhibition of DNA Methylation
Alters Cell Phenotype in Sexually Dimorphic Regions of the Mouse Brain Endocrinology April 7, 2017 Morgan Mosley, Jill Weathington, Laura R. Cortes, Emily Bruggeman, Alexandra Castillo - Ruiz, Bingzhong Xue, and Nancy G. Forger Many of the best - studied neural sex differences relate to differences in cell number and are due to the hormonal control of developmental cell death.
Conventional flow cytometry is a powerful technique for
measuring cell phenotype and function, but it relies on fluorescent stains, or labels, to identify particular cell subpopulations.
The Core Immunology Laboratory at Blood Systems Research Institute has focused on performing high - throughput immune assays
including cell phenotyping and sorting at our flow cytometry facility and soluble markers at our biomarker research facility.
The afternoon of the second day focused on somatic changes in melanoma, that is changes that occur in the tumour itself, and this session saw talks from ESR07 Sofia Chen on the mutational landscape of primary melanoma tumours; ESR08 Catarina Salgado on DNA hydroxymethylation (a form of regulation) in melanoma and naevi; and ESR10 Adriana Sanna on epigenetic regulation (reversible changes to the DNA which can turn genes on / off) of
melanoma cell phenotypes.
By 8 days of in vitro culture, such EPCs achieve a mature
endothelial cell phenotype (Figure 1B) and transition from a CD133high CD144low to CD133low CD144high cells (Figure 1C and 1D).
Computational classifiers trained between wild ‐ type cells and cells expressing Cas9 and gRNA enable the profiling of multivariate
single cell phenotypes.
Effects of conjugated linoleic acid isomers on monocyte, macrophage and
foam cell phenotype in atherosclerosis.
Notch - 1 induces Epithelial - mesenchymal transition consistent with cancer
stem cell phenotype in pancreatic cancer cells
MSC appear to evade allogeneic rejection by (a) being hypoimmunogenic; (b) modulating
T cell phenotype and (c) creating an immunosuppressive local milieu.
The increase of RPE cell markers in iPS - RPE was accompanied by the down - regulation of the iPS reprogramming molecules OCT4, SOX2 and NANOG expression (Fig. 1F and 1G), indicative of differentiation away from the
iPS cell phenotype.
Human Cancer Biology retracted paper «Characterizing the Clinical Relevance of an Embryonic Stem
Cell Phenotype in Lung Adenocarcinoma» — statistician: William Barry
Our work suggests that targeting a specific stem
cell phenotype, for example with immunotherapies, could be beneficial in patients with oligodendroglioma.»
«To describe some of
these cell phenotypes we were using lab words such as skinny wiggly cells, chubby wavy cells or zig - zagging sausages,» says Dr Grieneisen.
Taken together, these results strongly support a role for either a direct (T
cell phenotype) or indirect (DC phenotype) mechanism of immune modulation directed by MSC.
The impact of Ex Vivo clinical grade activation protocols on human T -
cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy.
Titles: 1) Notch - 1 induces Epithelial - mesenchymal transition consistent with cancer stem
cell phenotype in pancreatic cancer cells
Professor Dockrell and her group are investigating mechanisms that regulate the production of immune - related proteins, starting from gene regulation (epigenetics), gene expression (transcriptomics),
cell phenotypes (flow cytometry) and finally protein release.
Characterization of putative stem
cell phenotype in human limbal epithelia.