Prior to joining ViaCyte, Dr. D'Amour performed pre-doctoral research with Dr. Fred Gage at The Salk Institute where he studied stem
cell plasticity in neural stem cells.
Title:
Cell plasticity in Caenorhabditis elegans: from induced to natural reprogramming Authors: Hajduskova M, Daniele T, Ahier A and Jarriault S Date: 2012 Publication Details: Genesis 50 (1): 1 - 17.
Cédric Maurange, 2nd Call 2010 Institute of Developmental Biology of Marseille - Luminy Neural stem
cell plasticity in Drosophila
[email protected] +33 (0) 491 269 606
To identify the molecular mechanisms of neural stem
cell plasticity in adult zebrafish brain after various types of tissue damage or physiological stimulations
High - fat diet consumption during pregnancy and the early post-natal period leads to decreased < i > α
cell plasticity in the nonhuman primate.: High - fat diet causes decreased α cell plasticity.
Not exact matches
«
In animal studies, exercise has been shown to specifically affect the hippocampus, significantly increasing the growth of new neurons and cell survival, enhancing memory and learning, and increasing molecules that are involved in the plasticity of the brain,» Chaddock sai
In animal studies, exercise has been shown to specifically affect the hippocampus, significantly increasing the growth of new neurons and
cell survival, enhancing memory and learning, and increasing molecules that are involved
in the plasticity of the brain,» Chaddock sai
in the
plasticity of the brain,» Chaddock said.
According to Bean, study co-author Alexander Binshtok, a Harvard postdoctoral researcher
in neural
plasticity, is already at work eliminating capsaicin's negative effects by reversing the order of the injections: leading with QX - 314, quickly followed by capsaicin to shove it through the
cell.
Next, the team used other mouse models
in which part of the lung was removed and single
cell culture to study the
plasticity of
cell types during lung regrowth.
Moser demonstrated a number of changes
in the strength of connections between nerve
cells — a phenomenon called synaptic
plasticity —
in the hippocampus as rats stored information
in their long - term memory.
One hypothesis is that RNA molecules encoding proteins necessary for
plasticity are stored
in cell compartments close to the synapses, poised to be translated into proteins when needed.
The work, which appears
in the journal
Cell, focuses on the regulation of «neuronal
plasticity» — changes
in neuronal structure — and its function
in the brain.
Because these receptors are restricted to two distinct MSN populations, this postulate demands that synaptic
plasticity be unidirectional
in each
cell type.
But there are also neural stem
cells as well as early progenitors that have this
plasticity in most of the other systems of the body.
The researchers concluded that
in the early stages after stroke, improvements
in voluntary movement can be attributed to a reduction
in brain swelling because of the trauma and other spontaneous repairs, while later improvements result from «neuronal
plasticity» — the reorganization or regeneration of nerve
cells within the spinal cord
in response to changes
in the nerve network.
«Our results suggest that the location of the translational hotspot is a regulator of the simultaneous translation of multiple messenger RNAs
in nerve
cell dendrites and therefore synaptic
plasticity,» says Sul.
These factors are proteins that encourage
cell growth,
plasticity and survival, and therefore play an essential role
in controlling neuronal function.
Scientists have been attempting such a feat for years, refining their methods along the way, and the Irvine team finally saw success: the
cells were integrated
in the brain and caused large - scale rewiring, restoring the high - level
plasticity of early development.
It is not yet known whether the proliferation of the transplanted
cells accounts for the restored
plasticity or if the new
cells trigger
plasticity in existing neurons.
Using
cell culture assays and genetically modified mice, we identified a number of signaling proteins that participate
in muscle
plasticity.
In thinking about what molecules on the surfaces of
cells had both the
plasticity and molecular complexity to explain developmental programs, I knew it had to be the glycans.
When the researchers modeled the effects
in mice, they found it strengthened the connections between neurons that make learning possible — what is known as synaptic
plasticity — by increasing the action of a
cell receptor critical to forming memories.
For the type I interferon (IFN) receptor (IFNAR) as a paradigm for functional
plasticity, we have, within the first funding period, established single molecule imaging techniques for monitoring receptor assembly and dynamics
in the plasma membrane of living
cells.
The understanding of
cell identity, heterogeneity and
plasticity in neuroblastoma has strong implications with respect to the development of new therapeutic strategies to eradicate tumor
cells in neuroblastoma patients.
Anna Huttenlocher, University of Wisconsin, USA Neutrophils
in the Tumor Microenvironment Neutrophils, Wounds, and Cancer Progression Stefan Kaufmann, Max Planck Institute, Germany Pathology and immune reactivity: understanding multidimensionality
in pulmonary tuberculosis Constitutive BAK activation as a determinant of drug sensitivity
in malignant lymphohematopoietic
cells Kathryn Moore, New York University, USA MicroRNA -33-dependent regulation of macrophage metabolism directs immune
cell polarization
in atherosclerosis Lalita Ramakrishnan, University of Cambridge, UK Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment Beth Stevens, Harvard University, USA Microglia: Dynamic Mediators of Synapse Development and
Plasticity Do glia drive synaptic and cognitive impairment
in disease?
They have the
plasticity to differentiate
in to mesenchymal and non-mesenchymal
cell types alike, both
in vitro and
in vivo 5, 6, 7.
Furthermore, stem
cells in bone marrow may form not just hematopoietic
cells, but cardiac muscle
cells, neural
cells, and other types of
cells; this is an example of stem -
cell plasticity.
Researchers have discovered a new form of synaptic
plasticity, the changes to nerve
cells in the brain that underlie learning and memory.
Molecular mechanisms of stem
cell plasticity and regenerative neurogenesis
in adult zebrafish brain
This behavioural
plasticity allows all dividing
cells to participate
in tissue repair, making tissues resilient to injury.
Their work could pave the way for more effective prevention of heart attack and stroke
in humans caused by atherosclerosis,
in which artery walls thicken and suffer reduced
plasticity due to an accumulation of white blood
cells.
Title: «Hearts and bones»: the ups and downs of «
plasticity»
in stem
cell biology Authors: Bonfanti P, Barrandon Y, Cossu G Date: 2012 Publication Details: EMBO MOlecular Medicine 2012 May 4 (5): 353 - 361
Intrinsic
Plasticity Complements Long - Term Potentiation
in Parallel Fiber Input Gain Control
in Cerebellar Purkinje
Cells.
But novel genomic tools are beginning to reveal new, rare
cell types as well as unexpected variability and
plasticity within groups upending the traditional view of immune
cells assigned to the same category as unvarying entities that behave
in a constant manner.
Dr. Dean Tang Receives Sanofi -
Cell Research Outstanding Paper Award (11/04/2013) Dr. Dean Tang of the Department of Epigenetics and Molecular Carcinogenesis received the 2012 Sanofi - Cell Research Outstanding Review Article Award for his review paper entitled, «Understanding cancer stem cell heterogeneity and plasticity,» published in March, 2
Cell Research Outstanding Paper Award (11/04/2013) Dr. Dean Tang of the Department of Epigenetics and Molecular Carcinogenesis received the 2012 Sanofi -
Cell Research Outstanding Review Article Award for his review paper entitled, «Understanding cancer stem cell heterogeneity and plasticity,» published in March, 2
Cell Research Outstanding Review Article Award for his review paper entitled, «Understanding cancer stem
cell heterogeneity and plasticity,» published in March, 2
cell heterogeneity and
plasticity,» published
in March, 2012.
In general, adult stem
cells have low
plasticity, although reports of differentiation outside traditional lineage boundaries suggest that some adult stem
cells may be more pluripotent rather than multipotent.1
Nanog is a critical factor required for what
cell biologists call «stemness,» which is defined by two qualities: the ability of ES
cells to divide or «self - renew» and their
plasticity in assuming the identity of almost any
cell type, which is also known as «pluripotency.»
That process,
in turn, may generate «synaptic
plasticity» allowing the junctions between nerve
cells to strengthen and weaken more easily.
We used extracellular field potential recordings to study BST, short - term
plasticity (PTP, post-tetanic potentiation; PPF, paired - pulse facilitation) and long - term potentiation (LTP) at the Schaffer collateral - CA1 pyramidal
cell synapses
in young and old rTg4510 (2 - 3 and 6 - 7 month old) and old APP / PS1 mice (8 - 10 month old).
His research interests are phenotypic
plasticity, gene expression and
cell wall chemistry
in the freshwater green alga,
We will differentially characterize organelle structure and motility, excitability,
cell and axonal growth and
cell cortical
plasticity in the different diseases.
His research interests are phenotypic
plasticity, gene expression and
cell wall chemistry
in the freshwater green alga, Desmodesmus.
Chaired by Prof. Dirk Schadendorf, talks covered topics which included: melanoma epidemiology
in the
in period since the start of the German National Skin Cancer screening programme (Dr Andreas Strang); an overview of melanoma therapies used
in stage IV melanoma; adjuvant therapies and prognosis
in stage III melanoma (Dr Lisa Zimmer); tumour heterogeneity,
plasticity and resistance
in melanoma (Alexander Roesch); epigenomics of normal and abnormal
cell differentiation (Bernard Horsthermeke); and, genetics and epigenetics of uveal melanoma (Michael Zeschnigk).
Thus, although such genomically deranged conceptuses are unlikely to survive much beyond the implantation phase of pregnancy, the relatively large fraction (∼ 72 %) of successful pregnancies obtained at d 20 with
cell line 5538 (19) suggests that there is significant
plasticity in gene expression that can lead to successful implantation.
«These experiments with
cell type - specific pharmacology provide direct evidence for the necessity of NMDA - Rs
in dopamine neurons for the synaptic
plasticity observed 3 - 5 hours after exposure to cocaine
in vitro, leaving open the molecular explanation for the potentiation AMPA - Rs that occurs after many days of NMDA - R inactivity
in dopamine neurons
in vivo.
a)
In the subsection «Cell type - specific NMDA - R pharmacology in cocaine - induced synaptic plasticity» we now more clearly introduce the Zweifel and Engblom studies as well as the differences between them: both of which used genetic ablation of Grin1 over 1 week but showed different results with respect to DA neuron synaptic potentiation, which was due to methodological challenges with AMP - R compensatio
In the subsection «
Cell type - specific NMDA - R pharmacology
in cocaine - induced synaptic plasticity» we now more clearly introduce the Zweifel and Engblom studies as well as the differences between them: both of which used genetic ablation of Grin1 over 1 week but showed different results with respect to DA neuron synaptic potentiation, which was due to methodological challenges with AMP - R compensatio
in cocaine - induced synaptic
plasticity» we now more clearly introduce the Zweifel and Engblom studies as well as the differences between them: both of which used genetic ablation of Grin1 over 1 week but showed different results with respect to DA neuron synaptic potentiation, which was due to methodological challenges with AMP - R compensation.
2) The description of Engblom et al., 2008,
in the subsection «
Cell type - specific NMDA - R pharmacology
in cocaine - induced synaptic
plasticity» is misleading.
Depression is linked to a broad array of pathological processes, including inflammation of the peripheral nervous system structures, such as lymph nodes, as well as abnormalities
in synaptic
plasticity, which is the communication between nerve
cells.