Sentences with phrase «cell polarization»
Cell polarization refers to the process in which cells develop specific ends or regions with different functions. It's like when a cell picks a direction and decides which side will perform certain tasks. This helps the cell perform its functions effectively and efficiently. Full definition
Exposure of the epithelial monolayer to an apical fluid shear stress (0.2 dyne cm 2) that mimics that found in living kidney tubules results in enhanced epithelial cell polarization and primary cilia formation compared to traditional Transwell culture systems.
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PARD3 gene encodes a protein that regulates cell polarization and cell junctions.
The hematopoietic stem cell polarization and migration: A dynamic link between RhoA signaling pathway, microtubule network and ganglioside - based membrane microdomains.
As cellular junctions are one of the first specialized structures that form during tissue development they have a critical role in guiding cell polarization and differentiation.
More recently, another HDAC inhibitor, ITF2357, was shown to modulate IL - 6 — dependent CD4 + T cell polarization into Th17 cells through targeting the IL - 6 / STAT3 / IL -17 pathway, and it reduced the severity of experimental colitis (49).
In other major projects in the laboratory, we investigate the molecular mechanisms that regulate endothelial cell polarization and movement, a critical and initiating event in the formation of new blood vessels and in repair of injured vessels.
While the cell - extrinsic factor (s) that regulate myosin II's activity during T - cell migration in a confined environment have been poorly defined, a recent study using zebrafish germ progenitor cells showed that LPA induces cell polarization in a ROCK - myosin II - dependent manner, which enables rapid cell migration in a confined environment (Ruprecht et al., 2015).
More specifically, he researches the use of anti-CEA antibodies for tumor imaging and therapy, as well as the role of CEACAM1 in T - cell activation and mammary epithelial cell polarization.
In order to guide cells in a certain direction a signal from outside is needed, which leads then to cell polarization and coordinated mechanical movement.
The mechanisms controlling cell polarization are conserved, and the Drosophila fruit fly model has played a leading role in helping our understanding of the mechanisms controlling cell polarization during development.