Sentences with phrase «cell populations by»

However, as demonstrated by a recent report from Stuelten and colleagues [13], the complexity of CSC markers continues to pose challenges for identifying and isolating the putative tumor stem cell populations by the cell - sorting approach.

Quick and reliable assessment of chronological life span in yeast cell populations by flow cytometry.

It is a bulk method that sorts different cell populations by tuning their solubility.

Subsequent tests revealed that the treatment had reduced the visible cell population by a factor of 100 thousand, compared with an untreated cell culture, within the space of just 20 days.

Not exact matches

(i) a woman's right to choose; (ii) teaching evolution in school; (iii) medical immunization of teen girls against HPV; (iv) assisted suicide; (v) gay marriage; (vi) my right to view art and theatre deemed «offensive,» «blasphemous» or «obscene» by theists (vii) basic $ ex education for older school children; (viii) treating drug abuse as principally a medical issue; (xi) population control; (x) buying alcohol on a Sunday; (xi) use of condoms and other contraceptives (xii) stem cell research.

Sampling was conducted via a stratified dual frame probability sample provided by Survey Sampling International of landline and cell phone telephone numbers from within New York State weighted to reflect known population patterns.

In the new study, led by graduate student Steven Briscoe, the team found that other populations of neurons in the bird DVR share molecular signatures with neocortical intratelencephalic cells, or IT neurons.

The study, «Spectrophotometric analysis at the single - cell level: elucidating dispersity within melanic immortalized cell populations,» was supported in part by the Mizzou Advantage program, an initiative that fosters interdisciplinary collaboration among faculty, staff, students and external partners to solve real - world problems in four areas of strength identified at the University of Missouri, including Food for the Future, One Health / One Medicine, Sustainable Energy and Media of the Future.

He specifically wants to expand the population of stem cells that will induce regeneration of neurons and blood vessels in patients who have suffered a hemorrhagic stroke, the kind of stroke which is caused by blood clot.

«This strategy allows a colony to hedge its bets by enabling individual cells within a population to assume high levels of resistance while others avoid this extra work.»

Tanyi and colleagues made each patient's vaccine by sifting through the patient's own peripheral blood mononuclear cells for suitable precursor cells, and then growing these, in the lab, into a large population of dendritic cells.

The KU researcher said that new evidence suggests that cancer originates and progresses by a small population of cells known as cancer stem cells.

Most theorists assume that such a complex concept would have to be supported by large populations of cells, each of which corresponds to one component of the object (the bun, the bifocals, the leather miniskirt).

By using these and other high - tech tools, the researchers homed in on a unique population of T - cells that are highly prevalent in the joints of rheumatoid arthritis patients.

Saatchi, which is owned by France's Publicis Groupe, SA, chose LifeStraw over a field of competitors that included a reusable controller to improve the distribution of IV fluids, a collapsible wheel that can be folded down for easier storage when not in use on bicycles or wheelchairs, an energy - efficient laptop designed for children in developing countries, a 3 - D display that uses special optics and software to project a hologramlike image of patient anatomy for cancer treatment, an inkjet printing system for fabricating tissue scaffolds on which cells can be grown, a visual prosthesis for bypassing a diseased or damaged eye and sending signals directly to the brain, books with embedded sound tracks to help educate illiterate adults on health issues, a phone that provides telecommunications coverage to poor rural populations in developing countries, and a brain - computer interface designed to help paralyzed people communicate via neural signals.

Professor Gianni Liti, a senior author on the paper from the Institute for Research on Cancer and Ageing, Nice, said: «We were able to study the evolution in time by combining genome sequences of the cell populations and tracking the growth characteristics of the yeast cells.

Frey and his colleagues made use of mathematical models to analyze the complex interplay between ecological factors and population dynamics, and were able to demonstrate that populations can indeed respond in a coordinated fashion to chemical information even when the signal molecules are generated by only a subset of the cells.

By varying the compositions of lipids, cues, and diffusible factors in the scaffolds, we engineered a very versatile and flexible platform that can be used to amplify specific T cell populations from blood samples, and that could be deployed in existing therapies such as CAR - T cell therapies,» said Mooney, Ph.D., a Core Faculty member at the Wyss Institute and leader of its Immunomaterials Platform.

Led by Matthew P. Anderson, MD, PhD, Director of Neuropathology at BIDMC, the scientists determined how a gene linked to one common form of autism works in a specific population of brain cells to impair sociability.

By measuring for the presence of a molecule associated with cell division, the scientists determined that this residual population of dormant cancer cells consisted of an indolent as well as a quiescent population.

They might also come up with a way to select the right cells out of a mixed population; Anand Swaroop, an ophthalmology researcher at the University of Michigan at Ann Arbor, is working on a way to identify and weed out the photoreceptor cells by focusing on proteins present on cell surfaces.

Trapnell and Suzuki were prompted to test the novel macrophage transplantation therapy by studies showing that resident macrophage populations (such as those residing in the lung) can self - maintain without the cells having to regenerate directly from the bone marrow.

«By combining the genetic analysis of a small population of immune cells from healthy skin with functional experiments we were able to define two subgroups of memory immune cell and in detail decipher / dissect how these cells behave in healthy and inflamed skin,» explains Liv Eidsmo, researcher at Karolinska Institutet's Department of Medicine.

In Western society the population is growing older, the incidence of chronic disabilities which could be treated by stem cell therapy is steadily rising, and the availability of donor organs is not matching the need.

Now a team of engineers at MIT has developed a new way to deliver such vaccines directly to the lymph nodes, where huge populations of immune cells reside: These vaccines hitch a ride to the lymph nodes by latching on to the protein albumin, found in the bloodstream.

When challenged by a toxin or infection, the immune system screens this population for a match, then swiftly multiplies the clonal cell line that produces the matching antibody.

For that, they quantified how 85 nanoparticles delivered DNA barcodes to eight cell populations in the spleen, and found that cell types derived from myeloid progenitors tended to be targeted by similar nanoparticles.

«Ulcerative colitis is often associated with decreased mucus production and the worms seem to somehow restore mucus production, possibly by inducing a population of immune cells that make IL - 22,» Loke says.

By adding measured amounts of anhydrotetracycline (ATc) to a population of genetically modified yeast cells, scientists at the University of Texas M. D. Anderson Cancer Center were able to precisely control the production of green fluorescent protein.

The study revealed that in the model system chosen by Opitz and colleagues the winning side becomes apparent at a very early stage in the growth of the population, when the numbers of cells are still relatively small.

Located near the center of the brain, the nucleus accumbens is connected, by intermingled populations of cells, to many other brain structures having roles in pleasure seeking and drug addiction.

First, the number of toxin - sensitive cells in the starting population exceeds that of the toxin producers by a factor of 100.

Using sensitive live cell imaging, the team noted that endocytic waves initiated by clathrin emerge in some cell populations.

«We have discovered that by timing the inhibition of STAT3 — like an «on / off» light switch — we can transiently expand the satellite - cell population followed by their differentiation into mature muscle cells.»

The team also demonstrated the utility of the platform by applying it to examine a growth - modulating feedback circuit whose dynamics is qualitatively altered by circuit - host couplings and revealing the behaviors of a toggle switch across scales from single - cell dynamics to population structure and to spatial ecology.

Most theorists assume that such a complex concept must be supported by large populations of cells, each of which corresponds to one component of the object (the bun, the bifocals, the leather miniskirt).

By sequencing the genes of a population of cells that all contain the program, researchers can determine the magnitude and duration of the signal: The more cells have the genetic mutation, the stronger or longer the signal was.

The classical concepts of angiogenesis consider the endothelial cells within tumors as a rather passive cell population that merely reacts in response to growth factors released by the tumor cells.

Understanding the routes by which populations of brain cells share information would be a major step towards understanding how our brains function.

Now Prof. Daniel Offen and Dr. Adi Shruster of Tel Aviv University's Sackler School of Medicine have discovered that by reestablishing a population of new cells in the part of the brain associated with behavior, some symptoms of Alzheimer's disease significantly decreased or were reversed altogether.

The study, led by Katalin Susztak, MD, PhD, a professor of Renal - Electrolyte and Hypertension and Genetics, also identified three novel cell populations, along with all previously described kidney cell types.

By matching the microsatellite signature in a population of cells to those of known cells in the FACC - 29, a researcher can validate the identity of the cells used in research.

The R117H mutation, carried by about 3 percent the CF population, creates a protein that reaches its destination on the cell surface, but then malfunctions.

Dr. Angulo and his team plan to expand on their findings about this specific patient population by examining data beyond BMI, including fat distribution and differences in cell signaling proteins, such as cytokine and adipokine profiles.

These proteins are crucial for tissue healing by instructing various processes, including the activation of specific stem cell populations, ensuring that lung tissue can be restored to its original condition.

Scientists trained two rat populations — one with these cells intact and the other with them disabled — to fear a certain sound by giving them a mild shock every time it was played.

Interestingly, CD44 + / CD24 − population can be generated by induction of epithelial — mesenchymal transition (EMT) by treating breast epithelial cells with EMT - inducing agents such as TGF - β1 (6).

The adipocyte - enriched population (gray bars) expressed small amounts of the macrophage markers (a), consistent with residual macrophage contamination seen by immunofluorescent staining of live cells (b).

Events were gated as follows: singlets (FSC - A by FSC - H), live cells (SSC - A by Live / Dead), lymphocytes (FSC - A by SSC - A), CD3 + CD4 + (CD3 by CD4), and then events were divided into CXCR4 + and CXCR4 - populations based upon a fluorescence minus one (FMO) control.

It was at this stage that highly purified populations of endothelial cells could be obtained by adjusting the gating parameters to select only the most intensely labeled cells.