Sentences with phrase «cell proliferation during»

The most over-expressed gene in adipose tissue of diabetic co-twins was SPP1 encoding the inflammatory cytokine osteopontin, which recruits macrophages into adipose tissue and stimulates T - cell proliferation during inflammation (34).

However, the regulatory mechanisms of mammary epithelial cell proliferation during pregnancy have been unclear.

Not exact matches

During early pregnancy, hormones including progesterone, produced by the placenta, which is fetal tissue, cause proliferation of the milk producing cells within a mother's breasts.

Secretion of the hormones estrogen and progesterone set the stage for dramatic changes that take place in the breast during pregnancy: a massive proliferation of mammary epithelial cells, and the formation of thousands of ductal structures, which support milk production and transport during lactation.

However, it remains unclear how these different stem cells populations balance proliferation, differentiation and migration during the healing process.

Using a mouse model, the team also demonstrated that two processes during neurodevelopment are regulated by the gene: proliferation — the replication of neuronal stem cells that have the potential to become multiple different kinds of cells, including neurons — and migration — the movement of neurons to specific locations in the brain during development.

This program, resulting in shorter 3 ′ UTRs, is a characteristic of gene expression during immune cell activation and correlates with proliferation across diverse cell types and tissues.

Although beta cells proliferate robustly during the first decade or so of life, this proliferation slows dramatically with age.

When researchers suppressed the ARF gene in mole - rat cells during the reprogramming process to iPSCs, the cells stopped proliferation with sign of cellular senescence, while the opposite happens with mouse cells.

One of his latest studies, published in 2015, found that exposure to bright blue - white light during the day has the opposite effect of light exposure at night: It greatly enhances the release of melatonin and inhibits the proliferation of prostate cancer cells in an animal model.

«Taken together, these studies show that the NK cell IL - 10 response is associated with extensive proliferation, either under in vitro conditions independent of infection, or in vivo during infection,» wrote the authors, including co-lead author and former Brown postdoctoral researcher Seung - Hwan Lee, who is now at the University of Ottawa.

Their findings outlined four distinct cellular phases of sperm stem cells maturation, revealing how the stem cells progress from a «quiescent» state, to a «proliferation» state during which stem cells divide, to a final «differentiation» state when stem cells mature to become sperm.

In the case of planarians, the gene egr - 4 seems to perform an early control of cell proliferation as a response to amputation, and be involved later in the early differentiation of brain during regeneration.

«Probably, any molecule related to the nervous systems induce cell proliferation or differentiation during regeneration,» remarks Francesc Cebrià.

One of the key metabolic alterations that takes place during EMT is that of the epidermal growth factor receptor (EGFR) which is a pathway that regulates growth, survival, proliferation, and differentiation in mammalian cells.

The absence of tumors in virgin Nrk mutant mice strongly suggests that the tumorigenesis is closely related to the proliferation of mammary epithelial cells during pregnancy.

During pregnancy, the elevated blood estrogen level induces the proliferation of mammary epithelial cells, leading to the development of the mammary gland in preparation for lactation.

Canonical Wnt signaling promotes the proliferation and neurogenesis of peripheral olfactory stem cells during postnatal development and adult regeneration.

Reeh KA, Cardenas KT, Bain VE, Liu Z, Laurent M, Manley NR, Richie, ER (2014) Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis.

The appearances under phase - contrast microscope of human satellite cell cultures during proliferation and differentiation are shown in Figs. 1a and b. Cell cultures were allowed to differentiate for 4 days before cell cultures were exposed to the different insulin concentrations for 4 days as described in research design and methcell cultures during proliferation and differentiation are shown in Figs. 1a and b. Cell cultures were allowed to differentiate for 4 days before cell cultures were exposed to the different insulin concentrations for 4 days as described in research design and methCell cultures were allowed to differentiate for 4 days before cell cultures were exposed to the different insulin concentrations for 4 days as described in research design and methcell cultures were exposed to the different insulin concentrations for 4 days as described in research design and methods.

Smyd3 function is required for the activation of oncogenic pathways, cell proliferation and epithelial to mesenchymal transition during tumorigenesis.

Over again Cyclin D1 expression elevated during G2 phase which enables the cell to commit to continue the proliferation [10].

New data and research approaches have created opportunities for researchers to study in detail many aspects of cancer biology, including how the normal biological programs of cell proliferation and death are altered during cancer and how the immune system responds to tumors.

Conversely, few pro-apoptotic genes are expressed in ES cells (day 0; most boxes appear in green), but many are gradually induced during the differentiation process showing the exact opposite pattern from the genes involved in cell proliferation (Figure 7).

Together, this new data suggests that the missing endodermal cells observed at the end of gastrulation (Figure 1B) are not due to initial specification or proliferation defects but instead may result from an increase in cell death in toddler mutants during gastrulation.

Consequently, the normal rate of cell proliferation would have been decreased during protein deprivation, which is similar to the retardation of brain cell growth of young malnourished animals described by Winick and Rosso (18).

«the normal rate of cell proliferation would have been decreased during protein deprivation, which is similar to the retardation of brain cell growth of young malnourished animals.

«[T] he normal rate of cell proliferation would have been decreased during protein deprivation, which is similar to the retardation of brain cell growth of young malnourished animals.

During the follicular phase, estrogen stimulates proliferation of endometrial cells.