Sentences with phrase «cell proliferation in»

Data analysis using Baysian self - learning algorithm to narrow target genes suspected to be involved in stem cell proliferation in the stem cell niche of the gonad arm.

Titled, «Aromatic - turmerone induces neural stem cell proliferation in vitro and in vivo,» German researchers evaluated the effects of this turmeric - derived compound on neural stem cells (NSCs)-- the subgroup of brain cells capable of continuous self - renewal required for brain repair.

Effects of dietary wheat - bran fiber on rectal epithelial cell proliferation in patients with resection for colorectal cancers.

Lobelia also acts as an antidepressant by hindering cell proliferation in the hippocampus and inducing dopamine release in the brain.

The likely mechanism is that omega - 3 fats result in less inflammation and angiogenesis, and indeed when a very low - fat diet (15 % E) is supplemented with fish - oil prior to radical protatectomy, there was less cell proliferation in the excised prostates, despite no change to IGF - 1 levels.

Barnett JB, Dao MC, Hamer DH, et al: Effect of Zinc Supplementation on Serum Zinc Concentration and T Cell Proliferation in Nursing Home Elderly: A Randomized, Double - Blind, Placebo - Controlled Trial.

Indeed, we found that MELK overexpression in non-transformed HMEC - DD cells resulted in increased cell proliferation in suspension culture (Figure 4 — figue supplement 2A).

Since these proteins are known to be involved in the regulation of cell division, this study seeks information about their influence in regulating cell proliferation in the human corneal endothelium.

Balb / c splenocytes were used as third - party responder cells assuming that these would induce the same degree of T cell proliferation in tolerant and control animals.

Human NIAM is involved in chromosome segregation, p53 regulation and cell proliferation in somatic cells, but its role in embryonic stem cells is unknown.

Results from the previous times (Times 1 - 3) of the Swedish longitudinal OCTO immune study indicated that a combination of high CD8 and low CD4 percentages and poor T - cell proliferation in PBL was associated with a higher 2 - year mortality in a sample of very old Swedish individuals.

Follicular dendritic cells produce IL - 15 that enhances germinal center B cell proliferation in membrane - bound form.

The challenge to measure cell proliferation in two and three dimensions.

Removing two small proteins that put the brakes on cell proliferation in separate tissues can have deadly consequences, according to HHMI investigator James Ihle and colleagues at St. Jude Children...

To this end, we are focusing on two aspects of β - cell regeneration: enhancing β - cell proliferation in vivo and stimulating the differentiation of new β - cells from endogenous progenitors in the pancreas.

The major mechanism of B cell suppression by MSCs is attributed partly to the physical contact between MSCs and B cells and in part to the soluble factors released by MSCs; this leads to the blocking of B cell proliferation in the G0 / G1 phase of the cell cycle with no apoptosis 28, 29, 30.

Discrepancies between metabolic activity and DNA content as tool to assess cell proliferation in cancer research.

Increased transforming growth factor beta expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of Meth A sarcoma cells.

The Long Noncoding RNA SPRIGHTLY Regulates Cell Proliferation in Primary Human Melanocytes.

Lipton and colleagues now report that the p38 MAPK pathway is also the mechanism underlying decreased stem cell proliferation in the brain associated with HIV / AIDS.

«New family of small RNAs boosts cell proliferation in cancer.»

The authors say it is possible that the combination of having an older father and no siblings may promote cell proliferation in those individuals with an underdeveloped immune system and, as such, favors the development of cancers related to the immune system, like lymphoma.

Students in the UBC program engage in a wide range of research: molecular mechanisms underlying cell proliferation in cancer or cell death in stroke; relating gene mutations to disease mechanisms; the social factors that determine access to health care for women living on the street.

«Foxo1 is a tumor suppressor gene, but it promotes B cell proliferation in the germinal center,» he said.

Ever since Biron and colleagues published the first observations of NK cell proliferation in 1982, she has sought to figure out why it happens.

In March 2016, Penn researchers published a study in Blood that showed long - term ibrutinib treatment reverses the dysfunction of T cells in CLL and that combining CAR therapy with ibrutinib enhanced engineered T cell proliferation in mice.

Schematic illustration of cells (blue mountain - like shapes) on top of nanoscale mushroom - like structures with silicone dioxide stems and gold caps, which have the potential to detect cell proliferation in real - time.

EGF, TGF - alpha, and human milk stimulate fetal small intestinal cell proliferation in vitro, with the greatest increase in cell proliferation seen following exposure to human milk.

High dosages of reb A fed to rats reduced sperm production and increased cell proliferation in their testicles; however, another study using rats and humans demonstrated lack of reproductive toxicity.

Not exact matches

The proliferation of cell phones and ecommerce has disrupted traditional delivery services in markets around the world, particularly in emerging and frontier economies.

Their antioxidant activity is known to inhibit cell proliferation and invasion, and promote apoptosis (cell death) in various cancer cells.

Acute Psychosocial Stress Reduces Cell Survival in Adult Hippocampal Neurogenesis without Altering Proliferation.

Proliferation of the distal portions of the ducts results in the formation of multiple alveoli (which contain lactocytes — cells that secrete milk).

Transient Silencing of 14 -3-3sigma promotes proliferation of p63 - positive progenitor cells isolated from human breastmilk in mammary epithelial cell culture.

Secretion of the hormones estrogen and progesterone set the stage for dramatic changes that take place in the breast during pregnancy: a massive proliferation of mammary epithelial cells, and the formation of thousands of ductal structures, which support milk production and transport during lactation.

One of the team's new biosensors is made from a nanoplasmonic material that is able to accommodate a large number of cells on a single substrate and to monitor cell proliferation, a fundamental process involving cell growth and division, in real time.

Unlike the differential effect on Treg cell proliferation following PD - L1 blockage, the researchers observed an increase in the proliferation of killer T cells from all HIV study groups, regardless of their viral load.

In the placenta, RDGs have been found working in pathways associated with many of the tools of invasion: immune suppression, blood vessel growth, cell proliferation, and inflammatioIn the placenta, RDGs have been found working in pathways associated with many of the tools of invasion: immune suppression, blood vessel growth, cell proliferation, and inflammatioin pathways associated with many of the tools of invasion: immune suppression, blood vessel growth, cell proliferation, and inflammation.

The researchers were able to inhibit proliferation of the cells in vitro using the FGFR inhibitors PD173074 and pazopanib.

Furthermore, they found that by inhibiting Akt they could significantly slow cell proliferation, cell migration and cell invasion in the lung cancer and bladder cancer cells.

What if proliferation is the norm for cells — and a very different theory of cancers» cause is waiting in the wings?

In recent years it was also observed that it can function as a metabolic «signaler» that inhibits a biological pathway found in almost all higher life forms — the ability to sense when food has been eaten, energy is available and it's okay for cell proliferation, protein synthesis and growth to proceeIn recent years it was also observed that it can function as a metabolic «signaler» that inhibits a biological pathway found in almost all higher life forms — the ability to sense when food has been eaten, energy is available and it's okay for cell proliferation, protein synthesis and growth to proceein almost all higher life forms — the ability to sense when food has been eaten, energy is available and it's okay for cell proliferation, protein synthesis and growth to proceed.

In cell culture, high expression levels of GPR161 induced proliferation of mammary epithelial cells, disrupted the acinar structures formed by these cells, and enhanced their invasive capacity.

We will then seek to develop the most promising of these into novel drugs for cancers, such as those of the breast, where up - regulation of this c - FLIP is believed to be important in cancer cell proliferation.»

The underlying mechanism involves the activation of the immune system, resulting in local inflammation and proliferation of skin cells.

The researchers observed the effect of the synthetically produced molecule, JK - 31, on the growth and proliferation of a model human breast cancer cell line and found that it effectively blocked the protein cyclin - dependent kinase 1 (CDK1), which plays a key part in the process of the division of cancer cells, and therefore inhibited the proliferation of the cells.

Using a mouse model, the team also demonstrated that two processes during neurodevelopment are regulated by the gene: proliferation — the replication of neuronal stem cells that have the potential to become multiple different kinds of cells, including neurons — and migration — the movement of neurons to specific locations in the brain during development.

But the researchers also found that the new molecule intervened directly in the growth of the cancer itself, inhibiting a protein that controls the division and proliferation of malignant cells.

By using «gemcitabine» chemotherapy to target cancer cells, and a form of vitamin A to target the surrounding stromal cells, the combined approach led to a reduction in cancer cell proliferation and invasion.

A COMPOUND that slows the proliferation of triple - negative breast cancer cells in lab tests could lead to the first drugs to target this aggressive type of tumour.