Sentences with phrase «cell receptor determine»

«When you present the body with these arrays, the status of the cell receptors determines which effects predominate.

Not exact matches

He determined that epithelial cells lining the brain's blood vessel walls contain a surface protein, or receptor, that can snag insulin, the hormone essential for metabolizing carbohydrates and fats.

Hemagglutinin binds to glycan receptors found on the surface of respiratory cells, and the strength of that binding determines how effectively the virus can infect those cells.

To do this, they incorporated the gene sequence of each receptor into cultured cells and then probed the cells to determine if they were activated by one or more of 25 different bitter - tasting chemicals.

These receptors determine the differentiation of cell function and may increase the ability to produce insulin in response to glucose by beta cells.

In addition, Bettina Malnic of Harvard determined which receptor genes were active in individual nerve cells to learn which odor receptors were present in each.

Consequently, determining the functions that different receptors fulfil in the individual cell types is a complicated task.

Now, Skehel, along with colleagues at Harvard, Yale, and Emory University in Atlanta, Georgia, has used that sequence to build the virus's hemagglutinin (HA)-- a protein that latches onto receptors on the host cell surface — and determine its structure.

However, until now, the receptor to which it binds remained unknown, and the next big question was to determine which receptors the infected red blood cells were binding to.

Dr. Shiloh and his team currently are working to discover the human cell - surface receptors for Mtb that are involved in the bacteria's M - cell translocation, as well as to determine the exact machinery used by the cell to move the bacteria from the surface to the bottom of the cell.

Now, researchers have determined that an unstable chemical in crushed, raw garlic titillates two receptors on nerve cells that trigger pain — the same receptors that are stung by hot peppers and menthol.

This protein binds to human T - cell receptor CD4 in ELISA and Western ELISA as determined by CD4 / gp120 / Anti gp120 mAb - peroxidase capture ELISA.

Infant T cell repertoire analysis combines quantitative PCR to determine relative frequency of T cell receptor chain families with deep sequencing (LINK TO URI GSC) of the CDR3 region to evaluate clonal diversity within each family.

They determined that altering the expression level of LIGHT (a specific type of molecule that binds to a receptor site of another cell) and also lymphotoxin (LT) on T cells significantly impacted the cholesterol and triglyceride levels.

Although Wnts were better known because of their role as morphogens — proteins that pattern bodily structures and determine cell fates — Zou recently showed how members of the Wnt family served to guide pathfinding axons up and down the spinal cord by attracting or repelling receptors on the growth cones of sensory or motor nerves.

The ligand - receptor pairs which may determine the fate of the T cell include B7: CD28, ICAM - 1: LFA - 1, 4 - 1BBL: 4 - 1BB, OX40L: OX40, and CD40: CD40L (Croft and Dubey, 1997, Crit Rev Immunol).

Studies are being carried out to determine the functional effects that occur when these receptor - ligands interact; to determine how these proteins induce their activities at the molecular level and transmit signals to T cells; and to determine the significance of these proteins in several disease scenarios such as asthma, scleroderma, and atopic dermatitis.

We sequenced T - cell receptor Vβ genes in expanded microbe - reactive T - cell lines to determine their clonal diversity.

In this case (and others), I determine if the hypothalamus, pituitary, gonads (when it comes to testosterone), and / or cell receptors need support.