Sentences with phrase «cell receptor formation»

The team used a statistical model of T cell receptor formation to analyze receptor DNA sequences in blood samples from adult pairs of identical twins.

Not exact matches

Liang Xu, Ph.D. member of the KU Cancer Center's Drug Discovery, Delivery and Experimental Therapeutics program and associate professor of molecular biosciences at KU, has discovered that targeting a cell - surface receptor called «CD44s» can block pancreatic tumor formation and recurrence after radiotherapy.

The ions stimulate dozens of enzymes that reshape the cells by opening up additional receptors and by prompting the formation of more synapses and new protrusions that contain still more receptors and synapses.

This new piece of work published in Plos One and led by the UPV / EHU researcher Nerea Subirán describes for the first time the presence of opioid receptors in the cells involved in spermatozoon formation.

Using newly discovered information, the researchers made significant advances in developing a family of drug candidates that target a receptor known as peroxisome proliferator - activated receptors gamma (PPARγ), a key regulator of stem cells controlling bone formation and bone resorption and a master regulator of fat.

Some of the genes control receptors called integrins, which help cells attach to and communicate with one another, allowing formation of specialized organs and complex body plans.

When stimulated by molecules called fibroblast growth factors, this receptor, known as FGFR3, prevents the cells from maturing and impedes bone formation.

Now Mei and his collaborators have shown that rapsyn does not just help hold these receptors in place on the muscle cell, but also functions as an enzyme to help drive the formation of the neuromuscular juncture through a process called neddylation.

Intracellular interactions within the Golgi can lead to the formation of a complex between IL - 15 and IL - 15Rα, which can either be secreted or anchored to the cell membrane for trans - presentation to neighboring cells displaying IL - 2Rβ and γc receptors (21, 22).

T cell receptor ligation induces the formation of dynamically regulated signaling assemblies.

Skeletal muscle fiber formation, bone marrow stem cell formation, thymus T - cell formation, TNF - a / INF - gamma production by immune system's macrophages (immunosenescence by IGF loss), neuregulin and brain - derived neutrophic factor depend on IGF - 1 acting on brain IGFR receptors.

Formation of supramolecular activation clusters on fresh ex vivo CD8 + T cells after engagement of the T cell antigen receptor and CD8 by antigen - presenting cells.

We also found that the EphB4 receptor expressed on the surface of breast cancer cells can promote tumor xenograft growth by enhancing blood vessel formation through interactions with its preferred ligand, ephrin - B2, present in tumor endothelial cells.

Using CRISPR, the paper, published in the journal Blood, describes how genetic deletion of the T cells» endogenous receptor eliminates the competition it imposed on the engineered TCR and the possibility of dangerous hybrid TCR formation.

Silencing of the Oct4 promoter in P19 cells is a complex process, mediated by a combination of events including orphan receptor binding, DNA methylation, histone deacetylation, and heterochromatin formation [36], [37].

You also are not getting the high amounts of fatty acids and amino acids that enter the cell and interfere with insulin receptor production and glycogen formation.