Sentences with phrase «cell receptors in»

German Shepherds have 225 million cell receptors in their noses, making them ideal for police work and search and rescue activities.

The Harvard School of Public Health explains that omegas — 3 and — 9 «are an integral part of cell membranes throughout the body and affect the function of the cell receptors in these membranes.

explains that omegas — 3 and — 9 «are an integral part of cell membranes throughout the body and affect the function of the cell receptors in these membranes.

Until those binding proteins are stripped away, the hormone molecules can not bind to cell receptors in our tissues.

These forms are the only ones that can bind to cell receptors in breast tissue and everywhere else in the body.

SAN DIEGO, March 28, 2017 (GLOBE NEWSWIRE)-- Invivoscribe ® Technologies Inc., a global company with decades of experience providing internationally standardized clonality and biomarker testing solutions for the fields of oncology, personalized molecular diagnostics ®, and personalized molecular medicine ®, reports that its next - generation sequencing (NGS) LymphoTrack ® Assay kits are being used by its LabPMM ® clinical laboratories, pharmaceutical partners, and cancer centers to identify and monitor chimeric antigen receptor T - cells (CAR - T) and engineered T - cell receptors in peripheral blood of subjects in support of immuno - therapeutic drug development and treatment regimen development for both hematologic and solid tumors.

The process uses a computational model to generate predictions about the dynamics of cell receptors in different cellular compartments.

Internalization of B Cell Receptors in Human EU12 μHC.

To address this question, Sasisekharan and his team analyzed the structure of the H5N1 and H7N9 viruses, focusing on hemagglutinin (HA)-- a type of viral protein that binds to cell receptors in the respiratory tract of hosts.

For one, this can influence the ability of bile acids to interact with specific cell receptors in the intestinal lining.

He is part of the team that cloned the gene for the human T cell receptor in 1984, which he describes as «the Holy Grail of immunology.»

Although B - and T - cell development were normal, CD4 (+) T cells lacking Emk exhibited a marked upregulation of the memory marker CD44 / pgp -1 and produced more gamma interferon and interleukin - 4 on stimulation through the T - cell receptor in vitro.

Not exact matches

Kite Pharma, one of the companies chasing a new generation of cancer drugs called chimeric antigen receptor T - cell (CAR - T) therapies, announced a patient death in a clinical trial of its experimental KTE - C19.

Bellicum is among the flurry of biotechs investing heavily into cell therapies such as experimental chimeric antigen receptor T - cell (CAR - T) treatments for cancer (this is the next - gen treatment that involves reprogramming immune cells to become cancer killers and has shown promise in blood cancers, which Bellicum specializes in).

JCAR015 is a CD19 - directed chimeric antigen receptor technology (CAR - T) product candidate that has been under study in ROCKET in adult patients with relapsed or refractory B - cell acute lymphoblastic leukemia.

In my cell biology course, we investigate the biology and chemistry of a cell surface receptor that helps induce good feelings in us when it binds to a chemical compound found in incense; this may help explain why so many different cultures and religions have independently evolved the use of incense in their ceremonies and ritualIn my cell biology course, we investigate the biology and chemistry of a cell surface receptor that helps induce good feelings in us when it binds to a chemical compound found in incense; this may help explain why so many different cultures and religions have independently evolved the use of incense in their ceremonies and ritualin us when it binds to a chemical compound found in incense; this may help explain why so many different cultures and religions have independently evolved the use of incense in their ceremonies and ritualin incense; this may help explain why so many different cultures and religions have independently evolved the use of incense in their ceremonies and ritualin their ceremonies and rituals.

Specifically, when capsaicin frequently binds to receptors within the human central nervous system's TRPV1 channel (the sensory receptor system for pain and heat detection), these receptors deplete and this depletion results in a whole host of benefits for the central nervous system at large, including terminating cancer cells, increasing the metabolic rate and digestive efficiency, increasing circulatory blood flow, and combatting inflammation, and making you feel better about the world.

Every cell in the body have vitamin D receptors, which means that D - vitamin is very important for optimal health and the immune system.

Capsaicin only inflames human cells because heat - detecting proteins in our nerve endings called TRPV1 receptors become activated in the chemical's presence, mistakenly interpreting capsaicin as a sign of extreme heat, and sending the body's burn defenses into overdrive.

On the walls of the lactocytes (milk - producing cells of the alveoli) are prolactin receptor sites that allow the prolactin in the blood stream to move into the lactocytes and stimulate the synthesis of breastmilk components.

Receptor sites in the walls of the milk - producing cells of the alveoli stretch and prevent prolactin from entering to stimulate more breast milk production.

Researchers in England have found that in trace amounts, they activate estrogen receptors in cells, which in turn alters the activity of certain genes.

In particular, the PTPRF gene, which is known to suppress intracellular signals that are usually triggered by insulin binding to its receptor on the cell surface, may serve as a biomarker linking insulin resistance with insufficient milk supply.

Effects of myo - inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cells.

The AR - V7 variant is formed when an androgen receptor loses the end part of the receptor, called the C - terminal end; this is deleted due to an error in RNA processing in tumour cells, leaving only the beginning part of the receptor, the N - terminal end.

Two protein receptors (yellow, red) float in a cell membrane's lipid rafts (orange), which play a role in antidepressants» delay.

«Recent data have shown that a variant of the androgen receptor called AR - V7, found in tumour cells circulating in the blood of patients with metastatic CRPC, predicted resistance to treatment with enzalutamide and abiraterone,» she will say.

Baier looked at the genetic mutations in the «frozen» fish and found one in the glucocorticoid receptor, a protein that is found in almost every cell and that senses cortisol — a hormone involved in the stress response.

When similar analysis was performed on the db mice, it was found that the disrupted db gene was responsible for encoding a protein that functions as a leptin receptor: When it binds circulating leptin at the cell surface, it sets in motion a biochemical cascade inside the cell.

Those open spaces are so designed that the body finds it difficult to make an antibody that will be able to get in there and block the receptor sites that the virus uses to bind the cell.

The finding, Shahrara said, provides «strong evidence» that the binding of CCL28 to joint - lining cells carrying its corresponding receptor is a necessary step in angiogenesis.

But H5N1, well adapted to the higher temperatures and particular cell receptors found in chickens, does not spread from person to person.

«This is both time - consuming and often difficult, because the genetically modified receptors have to be expressed in living cells.

«In fact, 85 percent of the T cell receptors classified correctly had not previously been identified,» Thomas said.

Like many drugs, beta blockers target receptors embedded in the surface of cells.

For some years now, a new class of drugs called antibody - drug conjugates (ADCs) have been used, which work in two ways: they consist of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a chemical substance that enters the cancer cells with the antibody and triggers their death.

The investigators found that CCL28, which is over-produced in joints affected by rheumatoid arthritis, attracts the surface - lining cells that carry its receptor.

By hindering LMPTP, the drug reawakens insulin receptors on the surface of cells — especially in the liver — which normally absorb excess sugar from the blood when they detect insulin.

The paper, by V. Hegenauer at University of Tübingen in Tübingen, Germany, and colleagues was titled, «Detection of the plant parasite Cuscuta reflexa by a tomato cell surface receptor.»

Microglia are the only cells in the brain that express the receptor CX3CR1.

The tools included TCRdist, which researchers used to calculate the similarity and differences of key features of T cell receptors, such as amino acid sequences in important regions for antigen recognition.

Each person can have about 100 million different receptors, referred to as their T cell repertoire, with little overlap even in identical twins.

These receptors are found in the cell membrane and handle the communication between the outside and the inside.

The acid binds to the retinoic acid receptor, which is found in cells throughout the body.

They identified five receptors closely related to a class of receptor already known to help immune cells hone in on pathogens and inflammation.

The two postembryonic touch receptor neurons in the nematode Caenorhabditis elegans arise from essentially identical cell lineages and have the same ultrastructural features.

This drug (vedolizumab) blocks a specific adhesion molecule on the surface of the T - cell and thereby inhibits immune cells from binding themselves to receptors present in the intestine, preventing the T - cells from penetrating the blood vessels in the intestinal tissue.

Grouping T cell receptors for a given epitope revealed underlying common features that characterized the bulk of the repertoire,» said first author Pradyot Dash, D.V.M., Ph.D., a staff scientist in Thomas» laboratory.

Since genes for the T - cell receptor beta chain were previously shown to be on mouse chromosome 6, all three of the Ig - like multigene families expressed and rearranged in T cells are located on different chromosomes, just as are the B - cell multigene families for the Ig heavy chain, and the Ig kappa and lambda light chains.

Overexpression of p11 increases 5 - HT1B receptor function in cells and recapitulates certain behaviors seen after antidepressant treatment in mice.