Sentences with phrase «cell regulation in»

According to Singh, the discovery of the counteracting repression circuitry is likely key to understanding stem cell regulation in general.

Such counteracting repression circuitry may be the key to understanding stem cell regulation in general, Singh said.

Not exact matches

Venter, who created the first synthetic human cell back in 2010, feels the FDA hasn't found a way to serve the public in regard to genome data regulation — it barred 23andMe from offering genetic - risk assessments in 2013 before later reinstating the right to offer limited genetic reports.

The wireless industry has for years successfully fought regulations that would force mobile phone networks to be hardened so they work during storms, but it may face renewed demands after Hurricane Harvey knocked out seven of 10 cell towers in the hardest - hit counties of Texas.

Also functions as a hormone with roles in immune system health, insulin production, and regulation of cell growth.

He spent his last year as a Lisbon student studying cell - cycle regulation in yeast at the University of Manchester in the United Kingdom, with an Erasmus scholarship from the European Commission.

«xIAP has other roles in the cell, such as regulation of cell death, so it is a tricky target for treating inflammatory diseases.

The latest research in Science Signaling, covering cell signaling and regulation, synthetic biology, and drug discovery.

«The regulation of imprinted methylation results in these very consistent patterns in different tissues and even in a cell - type dependent manner.

The study also found that in addition to its role in determining the sex of somatic cells, Sxl regulation by m6A is required to initiate germline stem cell differentiation for developing eggs.

Without this regulation, lack of Sxl expression in stem cells can result in the development of ovarian cancer.

Researchers are now zeroing in on a promising missing link: mitochondria, the cell components responsible for energy regulation.

Hematopoietic stem cells, that form mature blood cells, require a very precise amount of protein to function — and defective regulation of protein production is common in certain types of aggressive human blood cancers.

By overlaying that information onto a computer model of the whole human genome, they were able to identify key factors involved in cell regulation

The genes we detect are involved in the regulation of cell development, and are specifically important in synapse formation, axon guidance and neuronal differentiation.

This system plays a major role in the regulation of gene activity, and enables the selective expression of different functions in differentiated cell types.

Although the regulation of this gene has a strong «cell cycle control» component, I was more interested in studying cell cycle regulation «proper.»

The study, recently published in Cell Metabolism, also found that beige fat, unlike the better - known white and brown fat, has interesting anti-diabetic effects on blood sugar metabolism that seem independent of temperature regulation.

«I was very curious at that point what glial cells would be doing in the hypothalamus, since glial cells have been shown in other brain areas to have an influence on regulation of neuronal function,» she says.

However, Brenner, who together with two others, has just received this year's Nobel Prize in Physiology or Medicine for their discoveries concerning «genetic regulation of organ development and programmed cell death,» maintains that nothing has changed for him.

Dr. Sade started her scientific career as a research fellow at the National Centre for Biological Sciences in Bangalore, India, where she investigated regulation of the survival and death of T cells.

One class of immunotherapeutic drugs is known as «checkpoint» inhibitors, as they target checkpoints in immune system regulation to allow the body's natural defenses, such as white blood cells, to more effectively target the cancer.

After having conducted a large - scale study performed on cells from the umbilical cords of 204 newborns, the researchers from UNIGE demonstrate that DNA methylation may play both a passive and active role in gene regulation.

She was on her way out to a pub after a scientific conference when she spotted Paul Nurse, who was working on cell - cycle regulation at Imperial Cancer Research Fund in London.

After graduating, he went to the University of California, Davis, and settled on investigating the genetic regulation of programmed cell death in plants.

«Our work suggests a mechanism for cell lethality involving the regulation of BCAAs as crucial elements in pancreatic cancer by regulating ME3,» said Ronald DePinho, M.D., professor of Cancer Biology, senior author of the Nature paper and president of MD Anderson.

We will then seek to develop the most promising of these into novel drugs for cancers, such as those of the breast, where up - regulation of this c - FLIP is believed to be important in cancer cell proliferation.»

Building upon their earlier research on the biology of fat metabolism, Joslin scientists discovered that microRNAs - small RNA molecules that play important roles in regulation in many types of tissue — play a major role in the distribution and determination of fat cells and whole body metabolism.

The following year, a paper by Ben Lehner's group at the Center for Genomic Regulation in Barcelona, Spain, drove the point home: When a cell produces too many of these proteins, they found, it dies.

In 1963, the couple moved to NYU to work as immunology research fellows in the lab of Baruj Benacerraf (who shared the Nobel Prize in Physiology or Medicine in 1980 for his work on the role of genetically determined, cell - surface structures in the regulation of immune reactionsIn 1963, the couple moved to NYU to work as immunology research fellows in the lab of Baruj Benacerraf (who shared the Nobel Prize in Physiology or Medicine in 1980 for his work on the role of genetically determined, cell - surface structures in the regulation of immune reactionsin the lab of Baruj Benacerraf (who shared the Nobel Prize in Physiology or Medicine in 1980 for his work on the role of genetically determined, cell - surface structures in the regulation of immune reactionsin Physiology or Medicine in 1980 for his work on the role of genetically determined, cell - surface structures in the regulation of immune reactionsin 1980 for his work on the role of genetically determined, cell - surface structures in the regulation of immune reactionsin the regulation of immune reactions).

The newly unmasked genes play a role in three distinctively different bodily functions, including systems that control inflammation and cholesterol and the regulation of how brain cells clean up toxic proteins.

Although NRF2 has many benefits, loss of NRF2 regulation leads to high levels in certain cancer cells, such as some lung cancers, and it may help them migrate, Zhang says.

Through the mTOR signalling pathway, it is involved in the regulation of many cellular processes, including cell survival, metabolism, proliferation, differentiation, and senescence.

They expressed concern that Japan «is in danger of being overtaken in the field of human iPS - cell research» because of government regulations.

Experiments in cells with an inactivated form of Argonaute — which contributes only to the antiviral and not the gene regulation activity of RNAi — confirmed that they were observing an antiviral RNAi response.

Regulations already in place in the European Union insist that stem cell therapies follow the same safety and efficacy rules as pharmaceuticals.

In the absence of any international body that would be an obvious fit to enforce international regulations on gene editing there are historical precedents — like stem cell research — for providing guidance and then leaving the specifics up to regional authorities.

And there are built - in obstacles to cell phone regulation.

Hass said SpDamID was developed to answer a number of important questions about Notch transcriptional regulation in the nuclei of mK4 cells.

Tufts Medical Center and Tufts University scientists have found exciting, new functions of the protein angiogenin (ANG) that play a significant role in the regulation of blood cell formation, important in bone marrow transplantation and recovery from radiation - induced bone marrow failure.

Teaming up with her friend Xianlin, they studied GADD45a, a gene involved in cell growth regulation.

Such precise regulation of the cell cycle is lost in cancer cells.

Particularly prominent in the RNA - Seq analysis was the up - regulation of a number of granzymes, a group of proteinases secreted by immune cells that were originally thought to be involved in killing (via apoptosis) virus infected cells or other target cells.

His group specialises in the study of the genetic and epigenetic regulation of female germ cell development.

This rapid, transmitter - mediated down - regulation of a cell adhesion molecule in the sensory neurons may be one of the early molecular changes in long - term synaptic facilitation.

Meanwhile the technologies needed to understand the regulation of fat accumulation in fat cells and thus the biological basis of obesity — specifically, techniques to accurately measure fatty acids and hormone levels in the blood — were not invented until the late 1950s.

Dr. Ella Evron and Dr. Ayelet Avraham of the TAU - affiliated Assaf Harofeh Medical Center, together with Prof. Saraswati Sukumar of Johns Hopkins, have found that «gene regulation,» the process that shuts off certain parts of a cell's DNA code or blueprint in healthy breast tissue cells, may also play a critical role in the development of breast cancer.

However, Dr Pullen and his team present evidence that plant growth is actually «sink - limited,» meaning that genetic regulation and cell division rates have a much bigger role in controlling plant growth than previously thought: «We are proposing that plant growth is not physically limited by Net Primary Productivity (NPP) or the environment, but instead is limited genetically in response to these signals to ensure they do not become limiting.»

SUGAR CHECK Artificial insulin - secreting cells (shown in this false color cryo - electron microscopy image) could offer automatic, ultrafine blood sugar regulation for diabetes patients.

Scientists from Trinity College Dublin have made a significant breakthrough in understanding the regulation of immune cells that play a pivotal role in allergic diseases such as asthma and eczema.