Sentences with phrase «cell reprogramming technology»

The company is developing a T - cell reprogramming technology designed to generate an anti-tumor response from the patient's own immune system.

Not exact matches

Further ahead, he is looking to an emerging technology known as induced pluripotent stem cells (iPSCs), in which adult cells are reprogrammed to be like embryonic stem cells so they can transform into any type of cell.

In addition to helping understand disease by providing more powerful study models, «what this technology would allow you to do is reprogram a skin cell, for example, from a Parkinson's patient... into a pluripotent cell and then in a petri dish redirect that cell into... a neuron» to treat that patient.

The new study, published in Nature Communications, also presents significant advancements in cellular reprogramming technology, which will allow scientists to efficiently scale up pancreatic cell production and manufacture trillions of the target cells in a step-wise, controlled manner.

The researchers also employed a cutting - edge technology developed by their collaborators at Columbia University to reprogram the child's skin cells into early progenitor cells, then differentiate those into lung cells, the front lines of influenza infections.

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

Ethicist Nigel Cameron of the Illinois Institute of Technology, an opponent of embryonic stem cell research, praises the reprogramming findings.

New gene - editing technology that successfully reprogrammed cells to fight leukemia in a 14 - weeks - old infant could be applied to other cancers

Scientists at the Massachusetts Institute of Technology (M.I.T.) report that they silenced symptoms of Parkinson's disease in rats using skin cells from an adult mouse that they reprogrammed to act like embryonic stem cells.

In medicine, the Institute's goal is to advance the science and engineering necessary to develop biomimetic materials, microdevices, microrobots, and innovative disease reprogramming technologies that emulate how living cells, tissues and organs self - organize and naturally regulate themselves.

It would also have been nice to see a mention of direct reprogramming, the latest stem cell technology that may one day make even iPSCs obsolete.

To answer this question, the Srivastava team took skin cells from the family and reprogrammed them using stem cell technology into beating heart cells.

In today's study, Dr. Ding focuses on reprogramming skin cells into β - cells using existing iPS cell technology — but with a twist.

One program will translate cellular reprogramming technology to the clinic to regenerate heart muscle cells in patients with heart failure.

His research interests are in the field of mammalian neural stem cells, reprogramming technology and adult neurogenesis.

In an attempt to bring patient - specific induced pluripotent stem cell (iPSCs) technology closer to the clinic, researchers have created iPSCs from patient - derived chondrocytes, using an non-integrative reprogramming method, and used these to then create large numbers of cartilage producing cells.

The Ogawa - Yamanaka Stem Cell Prize recognizes individuals whose original translational research has advanced cellular reprogramming technology for regenerative medicine.

Daley and other scientists are using iPS technology to reprogram cells from patients with diseases such as Lou Gehrig's disease (amyotrophic lateral sclerosis), Huntington's disease, and diabetes.

Topics covered include embryonic stem cells, pluripotency, germline stem cells, tissue - specific stem cells, stem cell differentiation, epigenetics, stem cell genomics and systems biology, genome reprogramming, cancer stem cells, stem cell niches, stem - cell - based disease models, nuclear transfer technology, bioengineering, drug discovery, in vivo imaging of stem cells, therapeutic applications, regenerative medicine, clinical and translational insights, stem cell research policies, ethical issues, and technical or resource - based innovations.

The University of Minnesota is setting up technology to work with the reprogrammed cells, said Jonathan Slack, director of the University's Stem Cell Institute.

At least one biotech company (iPierian) has been founded to exploit the commercial potential of these reprogramming technologies, and the Japanese government has established an entire research institute dedicated to fundamental and applied iPSC research (Center for iPS Cell Research and Application, Kyoto University).

The choice of the somatic cell for reprogramming, the reprogramming technology chosen, and the differentiation techniques utilised, all work synergistically towards the production of mature iPSCs - derived chondrocytes which are comparable to patient - derived chondrocytes, in line with Good Manufacturing Practice guidelines for an «off - the - shelf» stem cell product.

The new, US patent credits the Whitehead Institute's Rudolf Jaenisch, a scientific founder with Fate Therapeutics who licensed the technology to the company, and his former postdoc Konrad Hochedlinger, now at the Massachusetts General Hospital, with inventing a method for reprogramming cells

The breakthrough technology marks the first time that cells have been reprogrammed in a live body.

The technology reprograms cells through a device that uses nanotechnology.

Utilising both chondrocytes as a starting material and non-integrating mRNA technology as a reprogramming strategy, the group aimed to remove the risk of epigenetic memory of somatic cell of origin, which can affect future differentiation propensity, and reduces the risk of abnormalities being introduced during reprogramming.

This research was inspired by the Nobel Prize - winning technology of induced pluripotent stem cells (iPSCs) developed in Shinya Yamanaka's group, which showed how to reprogram skin cells into stem cells.»