Sentences with phrase «cell reprogramming through»

Reduced expression of Paternally Expressed Gene - 3 enhances somatic cell reprogramming through mitochondrial activity perturbation, Scientific Reports.

In a study published in the journal Proceedings of the National Academy of Sciences, Shinya Yamanaka, MD, PhD, who first created induced pluripotent stem cells (iPSCs), and his colleagues at the Gladstone Institutes found a way to increase the efficiency of stem cell reprogramming through research on a rare genetic disease.

Not exact matches

Researchers at the University of Edinburgh have pinpointed two molecules that boost reprogramming of cells — a process through which cells of one type can be converted to another.

Scientists have rolled back time for live mice through systemic cellular reprogramming, according to a study published December 15 in Cell.

One of the mechanisms being studied is reprogramming through cell fusion.

There are currently several lines of research that explore the possibility of tissue regeneration through cell reprogramming.

The sponge is implanted under the skin, and is designed to recruit and reprogram a patient's own immune cells «on site,» instructing them to travel through the body, home in on cancer cells, then kill them.

This webinar will cover the following topics: first, I will try to explain, in a few slides, the basic concept underlying direct lineage reprogramming; that is the reprogramming of one cell type into another without going through a pluripotent intermediate.

Understanding these pathways, and the identification of the key proteins that control the ability of cancer cells to reprogram their metabolism through biochemical, and epigenetic or genetic alterations that make them resistant to therapies, is of paramount importance for the design of more targeted and therefore less toxic therapies.

In vivo conversion of Müller glia into photoreceptors through cell fusion - mediated reprogramming.

Further, we have demonstrated for the first time that a cell's identity can be reprogrammed to convert into a completely unrelated lineage, without their removal from the body (in vivo) and without passage through a stem cell intermediate.

Melton is also a pioneer in direct cellular reprogramming research — the transformation of one type of adult cell into another, without first going through a stem cell state.

Many, if not all, oncogenes and tumor suppressor genes induce metabolic reprogramming in cancer cells through changes in the regulation of enzymes and transporters.

Created in 2005 through a collaboration between Inserm — National Institute of Health and Medical Research — and AFM - Telethon — French Association against Myopathies — I - Stem is the largest French laboratory for research and development dedicated to human pluripotent stem cells, of embryonic origin or obtained by reprogramming gene.

And two studies published this summer in Nature Biotechnology found that direct conversion methods to produce neural stem cells that employ the traditional reprogramming genes actually pass the cells through a pluripotent step.

The technology reprograms cells through a device that uses nanotechnology.