Sentences with phrase «cell research affect»

How does the government's limits on embryonic stem cell research affect you?

Not exact matches

The early stage research involves mice and yeast and centers on how diet affects aging and health and how cell aging leads to cell breakdowns.

Power has not been fully restored, affecting Garcia - Arraras» own samples of monoclonal antibody cell lines collected for organ regeneration research.

A growing body of research indicates that the B2M - MHC I complex, which is present in all cells in the body except red blood cells and plasma cells, can act in the brain in ways not obviously related to immunity — guiding brain development, shaping nerve cell communication, and even affecting behavior.

Since pseudouridine modifications may affect various RNA molecules in different types of normal and malignant cells, «our discoveries pave the way for future avenues of research aimed at exploring the role of pseudouridine in human development disease,» concludes Cristian Bellodi.

Today in Cell and associated journals, 24 research studies from the landmark BLUEPRINT project and IHEC consortia reveal how variation in blood cells» characteristics and numbers can affect a person's risk of developing complex diseases such as heart disease, and autoimmune diseases including rheumatoid arthritis, asthma, celiac disease and type 1 diabetes.

The research is also the first to demonstrate beneficial effects of UDCA on dopaminergic neurons, the nerve cells affected in Parkinson's disease, in a fly model of Parkinson's disease which carries the same genetic change as some patients with the condition.

They impact on signal transmission from cell to cell, but also affect intracellular communication,» explains Professor Robert Ernst, whose research group at the BMLS has been on the trail of fats» hidden functions for years.

«Our research has identified a gene affecting another type of ischemic stroke, due to small vessel disease, and also suggests some genes may be associated with both ischemic and hemorrhagic stroke and may act through a novel pathway affecting pericytes, a type of cell in the wall of small arteries and capillaries.

Center for Nuclear Receptors & Cell Signaling (CNRCS) Assistant Professor Daniel Frigo and his research team recently published a study investigating the processes through which androgen receptors affect prostate cancer progression.

Xinde Zheng, a research associate in the Hunter lab, was already studying the properties of cells affected by Leigh syndrome, whose inherited neurodegeneration is caused by a mutation in mitochondrial DNA that reduces ATP production.

To better understand how HMGA1 affected the rodents» intestines, Resar and Lingling Xian, M.D., Ph.D., research associate at the Johns Hopkins University School of Medicine, and their colleagues examined the transgenic animals» intestinal cells to determine which ones were expressing this gene.

«In the study we challenged the view that the age - dependent impairment in glucose homeostasis is solely due to intrinsic, dysfunction of islet cells, and hypothesized that it is instead affected by systemic aging factors,» says first author Joana Almaca at the Diabetes Research Institute, University of Miami.

«Contrary to previous studies, diabetes affects diaphragm, smooth muscle cells differently: Discovery could lead to better research of respiratory failure in individuals with diabetes.»

A new study published in eLife and headed by Jordi Casanova and Sofía J. Araújo, both scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the Instituto de Biología Molecular de Barcelona (IBMB - CSIC), describes a cell communication mechanism that allows the organisation of the extracellular matrix and how this structure affects cells through a feedback system.

This work, conducted by Yuliang Wang, now a senior research associate at Oregon Health & Science University, uncovered intriguing differences involving genes that affect the cells» metabolism.

The research suggests that reducing production of the protein, called myoferlin, affects cancer cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells — including their shape and ability to invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.

«Because many broadly expressed genes that play key roles in essential cellular functions are under the control of cell - specific enhancers, the ability to affect enhancer function by knocking down eRNAs could potentially provide a new strategy for altering gene expression in vivo in a cell - specific manner,» said Glass, noting that in his research, anti-sense oligonucleotides were developed in conjunction with Isis Pharmaceuticals, which suppressed enhancer activity and reduced expression in nearby genes.

«This means we can study how a cell affects its neighbouring cells,» says Orane Guillaume - Gentil, a postdoc in Professor Vorholt's research group.

Some basic research findings are being translated into new treatments, and with the discovery of induced pluripotent stem cells in 2006, the field has seen a step - change in biological understanding that will affect the way new drugs are identified and tested and, potentially, the way cells can be generated in the lab.

New preclinical research on the molecular mechanisms responsible for sickle cell disease could aid efforts to develop much needed treatments for this devastating blood disorder that affects millions worldwide.

Research from other scientists at Johns Hopkins, he says, had suggested that some tumors, particularly those that affect the nervous system, have mutations in the ATRX gene, which produces proteins that appear to maintain the length of telomeres, repetitive segments of DNA on the ends of chromosomes that typically shorten each time a cell divides.

At Emory, the pause has halted not only the CEIRS project with the lab - attenuated PR8 strain, but also a research grant project headed by Anice Lowen that is looking at how the cell types targeted by two different influenza viruses affect their propensity to exchange genes.

Professor Bowles, who referred to the research in a panel discussion on «Nature's Marvellous Medicines» at the recent Royal Society Summer Science Exhibition, said: «We were measuring how flavonoids affected the production of inflammatory mediators by cells stimulated by microbial products.

The research team led by Prof. Fiona Doetsch at the Biozentrum of the University of Basel has now shown that the choroid plexus is a key component of the stem cell niche, whose properties change throughout life and affect stem cell behavior.

«Scientists find what might be responsible for slow heart function under general anesthesia: New research in The FASEB Journal suggests that general anesthesia targets certain amino acids on proteins of the heart muscle fibers and cells which directly affects the ability of the heart to pump.»

«New research helps explain why a deadly blood cancer often affects children with malaria: Immune responses to malaria - infected red blood cells appear to sometimes lead to cancer - promoting changes.»

Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden.

The research confirms that IGF - 1 acts directly on T - reg cells — rather than indirectly by affecting some other factor that induces T - reg cells to multiply.

These research findings deliver new insight into the neuronal control of movement termination in vertebrates: «Stop cells» are brainstem neurons that affect neural networks in the medulla as command neurons and quickly end body activity.

The research, using cells from the Breast Cancer Now Tissue Bank and due to be published in Nature Communications, also shows that the epigenetic changes are inherited as long as the cell divides, and that the team's manipulations permanently and negatively affected the biology of a normal breast cell from a healthy individual.

New research out of Duke University shows that RNA viruses are littered with N6 - methyladenosine tags which affect the ability of these viruses to infect cells and, ultimately, their human hosts.

By performing DNA sequencing of more than 4,000 families affected by neurological problems, the two research teams independently discovered that a disease marked by reduced brain size and sensory and motor defects is caused by a mutation in a gene called CLP1, which is known to regulate tRNA metabolism in cells.

Using pig teeth and human young permanent tooth pulp cells, the research has identified that local anaesthetics commonly used in clinics can affect the proliferation of tooth cells.

Reporting in the Journal of Clinical Investigation Insights, a team led by senior author Andrea Facciabene, PhD, a research assistant professor of Radiation Oncology and Obstetrics / Gynecology, found that the effectiveness of adoptive T cell therapy (ACT) in mice with cancer is significantly affected by differences in the natural makeup of gut bacteria and treatment with antibiotics.

New research reveals that in pregnant women, Zika virus infection damages certain cells that affect placental formation and function.

The work was performed in collaboration with Arjan Narbad's lab at the Institute of Food Research in Norwich, UK, who tested how engineering mutations in the endolysins affected their ability to tear down the bacterial cell wall.

The Mayo Clinic has received $ 3 million from the Glenn Foundation for Medical Research to study how the presence of a specific sort of human cell affects aging.

New research quantifies the proteins» interactions and how they affect their flow within the cell.

From a basic research perspective, we have found the first example of a tumor - initiating mutation that directly affects how cells divide, causing chromosomal instability.

Our research centers upon the proteins affected in tuberous sclerosis complex (TSC) and spinal muscular atrophy (SMA)-- two neurological disorders whose genetic basis is well understood but whose cell biology remains unknown.

«This is an exciting time for stem cell research, and I am confident that Deepak will continue to promote the field, as our research leads to better treatments for diseases affecting millions of people around the world.»

The research team at Mainz University speculates that whilst entanglements between chromosomes need to be removed for cell cycle progression those within a chromosome may not affect function and transmission of genetic information.

Such techniques have the potential to enhance research into the origins of neurodevelopmental and neuropsychiatric disorders such as microcephaly, lissencephaly, autism and schizophrenia, which are thought to affect cell types not found in the mouse models that are often used to study such diseases.

A research team led by Prof. Dr. Prasad Shastri at the University of Freiburg has shown that the stiffness of the cancer cell plasma membrane affects how nanoparticles are internalized, and this process can be enhanced when the cell plasma membrane stiffness is increased.

In the next decade, molecular research is going to further develop along five lines: predictive medicine, that investigates the genetic conditions predisposing to tumor risk; early molecular diagnosis; the evaluation of each patient's prognosis based on his / her genetic profile, in other words, the analysis of what kind of mutation affects the DNA of altered cells; the investigation of the individual response to drugs, based on our genetic knowledge; «smart drugs», molecules able to hit the target in a selective way, killing only the deprogrammed cells.»

Moreover, research to be published soon might show small but perhaps crucial differences between induced pluripotent stem cells and the embryonic variety that could affect potential applications.

Scientists developing new cell therapy methods for the treatment of disorders such as sickle cell disease or leukemia need to consider how their culture conditions may affect the success of their translational research.

A transcriptome research of its organs revealed its gene signature is highly evolved and adapted for extreme longevity (slow metabolism, improved insulin gene signaling and glucose homeostasis, thus reduced blood glucose, improved cancer genes, improved endothelial function by eNOS (endothelial Nitric Oxide Synthase) meaning improved vascular coronary blood flow, improved microvasculature arterial and heart endothelium function) but more importantly, to answer your question, some whales display low blood glucose hypoglycemia, this affects the quantity and period of proteins / DNA / cell exposure to glucose glycation, glycosylation and glycoxydation reactions.

As a group, the Catalyst For a Cure research team was able to show that the primary cell that's affected in glaucoma, the retinal ganglion cell, does not die early in the stages of the disease.