Stem
cell researchers maintain that whatever the potential of adult stem cells, embryonic research could help them achieve it.
Not exact matches
Deep in one of the facility's 10 liquid nitrogen freezers, which hold samples for the university's
researchers so they don't have to
maintain their own
cell banks, was a sample that had been taken many years before from a child who died from an undiagnosed illness.
Using this mixture, the
researchers were able to print living
cells in a specific architecture, such as an ear shape, that
maintained its form even after printing.
Now
researchers at the University of Plymouth, working in partnership with pharmaceutical company AstraZeneca, have for the first time successfully cultured and
maintained cells from the guts of rainbow trout, a recommended fish species for toxicological studies.
In a study in the current issue of the Journal of Neuromuscular Diseases,
researchers treated these stem
cells with leukemia inhibitory factor (LIF), which effectively
maintained the undifferentiated state of the satellite
cells and enhanced their transplantation efficiency.
Now, for the first time,
researchers at the La Jolla Institute for Allergy and Immunology identified a molecular pathway that
maintains the stability and function of Treg
cells.
Researchers aren't quite sure how they
maintain their own 24 - hour schedule, whereas other
cells need external reminders.
«It is possible the
researchers simply have not worked out adequate methods to
maintain these
cells long - term in culture,» he says.
Researchers from the University of Twente MESA + research institute have now found a method that allows them to ensure that living
cells — in this case bacteria from the human body — can be incorporated in materials while
maintaining their mobility.
Researchers found that the protein YY1 brings Xist RNA back to the inactive X chromosome to
maintain X chromosome inactivation in stimulated B
cells.
Using a nuclear protein expressed in follicle stem
cells (FSCs), the
researchers found that castor, which plays an important role in specifying which types of brain
cells are produced during embryonic development, also helps
maintain FSCs throughout the life of the animal.
In a study,
researchers found that pigs, which have gut bacterial profiles and immune systems similar to humans, also
maintain two distinct colonic stem
cell populations — ASCL - 2 and BMI - 1.
Some
researchers speculated that
maintaining higher levels of donor immune
cells for longer could help to improve the success rate.
The
researchers then came up with a recipe for their 3 - D ink, using a combination of bacteria, hydrogel, and nutrients to sustain the
cells and
maintain their functionality.
The
researchers, based at Tsinghua University, Beijing, China, and Drexel University, Philadelphia, USA, used extrusion - based 3 - D printing to produce a grid - like 3 - D structure to grow embryoid body that demonstrated
cell viability and rapid self - renewal for 7 days while
maintaining high pluripotentcy.
In a new study published in Science Advances, a group of University of Wisconsin - Madison
researchers show that individual
cells in the human body have an armament designed to prevent HCMV from achieving and
maintaining this latency, to shine a spotlight on the virus so the immune system knows to fight.
To use RNAi against the pest, the
researchers first identified a gene the insect can't do without — one that encodes a cytoskeleton protein vital to
maintaining a
cell's shape.
The
researchers discovered that this region is required to both turn Sox2 on, and for the embryonic stem
cells to
maintain their characteristic appearance and ability to differentiate into all the
cell types of the adult organism.
Researchers running clinical trials planned to stop enrolling new patients, and furloughs were scheduled for all but about a quarter of NIH's 19,000 staff members, who were deemed «essential» to care for patients and
maintain animals and
cell lines.
Researchers from the University of Missouri School of Medicine have identified a molecular mechanism that operates in memory T
cells that could be manipulated to produce and
maintain more memory T
cells in the body, a finding that could improve vaccinations and cancer immunotherapies.
Researchers from Turku, Finland, have discovered new information about the mechanisms which
maintain gene activity in human embryonic stem
cells.
Now,
researchers from the University of Missouri School of Medicine have identified a molecular mechanism that operates in memory T
cells that could be manipulated to produce and
maintain more memory T
cells in the body, a finding that could improve vaccinations and cancer immunotherapies.
Researchers from the University of Seville at the Andalusian Centre for Molecular Biology and Regenerative Medicine (Centro Andaluz de Biología Molecular y Medicina Regenerativa — Cabimer) have discovered that in eukaryotic
cells the proximity of the genes to the nuclear pores, which are found in the nuclear membrane, contributes to
maintaining the integrity of the genome.
Researchers from the University of Michigan and the Mayo Clinic studied rat IEC - 6 intestinal epithelial
cells, chosen because they
maintain a stable diploid genomic structure (two sets of chromosomes), lack the cellular characteristics of cancer
cells, and replicate normally.
In a new study being presented at The Allied Genetics Conference in Orlando, Florida,
researchers report new insights about the underlying drivers that help
cells heal and
maintain their shape.
Scientists at the university
maintain the store and supply other
researchers with
cells on request.
Cystine is responsible for
maintaining high levels of antioxidants that disarm free radicals of oxygen; so when the
researchers got rid of this nutrient, the cancer
cells essentially died by their own hand of free radical damage.
«I'm interested in understanding how single
cells maintain their proper shape,» said Athena Lin, graduate student at the University of California, San Francisco, and lead
researcher on the project.
In this proof - of - principle study, the
researchers showed, using DNA sequencing and karyotyping technologies, that the patient's unique
cell characteristics were
maintained in both normal and tumor CR laboratory
cells.
A protein may be the key to
maintaining the health of aging blood stem
cells, according to work by
researchers at the Icahn School of Medicine at Mount Sinai recently published online in Stem
Cell Reports.
A new fabrication method enabled
researchers to make larger perovskite
cells with few defects, helping to
maintain efficiency at larger
cell sizes.
When using a well established model of colorectal cancer, the
researchers observed that dietary emulsifier consumption was sufficient to make the animals more susceptible to developing colonic tumors because this created and
maintained a pro-inflammatory environment associated with an altered proliferation / apoptosis (
cell death) balance.
The
researchers are manipulating
cells so that they can look at direct contact between two
cell membranes or precisely control and
maintain a variety of distances between
cells and determine how
cells communicate.
The
researchers tested the drug on mice with H. pylori infections from several different
cell lines, and found that the drug was effective against the H. pylori while
maintaining populations of healthy gut bacteria.
To test whether the
cells would
maintain their multipotency in living animals, the
researchers transplanted them into mice whose white blood
cells had been depleted, and showed that the new
cells could expand and differentiate into various types of white blood
cells.
Researchers identify a network of a dozen transcription factors needed to
maintain the pluripotent state of mouse embryonic stem
cells.
The Joslin
researchers «reprogrammed» the fibroblasts into iPSCs by using viral procedures that activated four genes that together
maintain cells in the iPSC state.
«This discovery will advance our understanding of stem
cell epigenetics and chromatin structures, provide potential mechanisms on
maintaining the hallmark properties of ES
cells, and help
researchers with the rich source of information to better understand some of the unique features — such as self - renewal and pluripotency — of human embryonic stem
cells,» said Ng Huck Hui, Ph.D., senior group leader at GIS and a member of the Singapore team that conducted this research.
Under a two - year project,
researchers at Pacific Northwest National Laboratory (PNNL) are collaborating with the Walter Reed - Windber Clinical Breast Care Project to find and compare the proteins of cancers that enable
cells to
maintain or spread the disease throughout the body.
Researchers also provided new details of how the Nrp1 pathway functions, including evidence that along with bolstering the ability of regulatory T
cells to suppress the immune response, the pathway also helps
maintain a stable population of regulatory T
cells.
However,
researchers from the laboratory of Nenad Bursac (Duke University, Durham, NC, USA) have recently described the production and differentiation of induced myogenic progenitor
cells (iMPCs) from hPSCs into the first entirely hPSC - derived 3D muscle tissues that survive, vascularize, and
maintain function following transplantation [5].
The
researchers were able to
maintain the production of Lsd1 in fat
cells, thus reducing age - related transformation of brown fat
cells to white fat
cells.