Each story is described through interviews with stem
cell researchers who were directly involved or appeared on the scene later but can knowledgably discuss the event's impact.
The injunction case was brought by two stem
cell researchers who complained that NIH's 2009 ESC research guidelines violated the law.
Not exact matches
For a small study published in March in the journal Aging
Cell,
researchers looked at 125 amateur cyclists aged 55 to 79, comparing them with 75 people of a similar age
who rarely or never exercised.
In 2014, a team of
researchers at UCLA led by genetics
researcher, Steve Cole, discovered that the
cells of people
who experience chronic loneliness appear to be stuck in a state of fear.
In the June 2010 issue of Nature Medicine, in an interview with theBoston - based
researcher, Daley tells how he further changed the focus of his work after Prof. Shinya Yamanaka of Kyoto University,
who won the 2010 Kyoto Prize for advanced technology, made known his successes with iPS
cells in 2007: «Once Yamanaka solved the problem, I turned around virtually my entire programme to take advantage of that breakthrough,» he says.
First, the interns will gather information about research institutions, academic
researchers, and companies conducting work in adjacent research areas (e.g.
cell therapy company)
who are currently using technologies that are applicable to plant - based and clean meat research or food technology.
Frankenbunnies Embryos made by Chinese
researchers who fused human skin
cells with rabbit eggs, hoping to create a source of stem
cells.
Deep in one of the facility's 10 liquid nitrogen freezers, which hold samples for the university's
researchers so they don't have to maintain their own
cell banks, was a sample that had been taken many years before from a child
who died from an undiagnosed illness.
They would add a liter of the tissue to two liters of seawater and shake the mixture 75 times — no more, no less — to make «the individual light - producing
cells pop out of the tissue,» according to Bill Ward, a bioluminescence
researcher at Rutgers University in New Jersey
who was a post - doc in Cormier's laboratory.
Demand for the therapy is also spurring competition for the
researchers and technicians
who create the
cells.
In a head - to - head clinical trial comparing standard chemotherapy with the immunotherapy drug nivolumab,
researchers found that people with squamous - non-small
cell lung cancer
who received nivolumab lived, on average, 3.2 months longer than those receiving chemotherapy.
Through a variety of «high tech» approaches, including the isolation of monoclonal antibodies from single B
cells and ultra-deep sequencing of shifting viral populations over more than three years of infection, the
researchers studied one woman
who developed potent broadly neutralizing antibodies.
The study «provided the surprising result that one new therapy currently being explored to lower insulin resistance promotes, rather than decreases, the formation of bone in mice,» says Darwin Prockop, a stem
cell researcher at Texas A&M College of Medicine in Temple,
who was not involved in the work.
According to Izpisúa Belmonte,
who is also a professor at the gene expression laboratories of the Salk Institute for Biological Studies in San Diego, California, CMRB aims to become «a research centre of excellence in south Europe in the line of world - recognized institutions such as the Salk or the Whitehead institutes, where both pre - and postdoctoral
researchers receive multidisciplinary training of the highest quality» in stem
cell biology and
cell regeneration.
The
researchers found that radiosurgery controlled the spread of the cancerous
cells as effectively as whole - brain radiation; patients
who received radiosurgery experienced less cognitive decline compared to those
who received whole - brain radiation.
In science news around the world, scientists march in India to call for more research funding, a South Korean
researcher who was enmeshed in a stem
cell scandal a decade ago resigns from a newly created government position, Canada establishes a vast marine conservation area in the High Arctic, a highly regarded advocate for science is convicted of financial misdemeanors in Egypt, and more.
By redirecting that energy to a genetically modified part of the
cell capable of producing various complex chemical materials, we induce the light driven biosynthesis of these compounds,» says Post Doc Agnieszka Janina Zygadlo Nielsen,
who along with colleagues Post Doc Thiyagarajan Gnanasekaran and PhD student Artur Jacek Wlodarczyk has been the main
researcher behind the study.
Researchers at Dana - Farber / Boston Children's Cancer and Blood Disorders Center report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure
who received a hematopoietic stem
cell transplant (HSCT) after pre-treatment with immunosuppressive drugs only.
The
researchers obtained stem
cells from the discarded fat of liposuction patients
who underwent elective surgery.
The Duke
researchers who made this discovery say it may help explain how a relatively small number of genes can create the dazzling array of different
cell types found in human brains and the nervous systems in other animals.
In people
who age prematurely, changes in the way that DNA is tightly packed in
cells leads to mayhem that promotes the aging process,
researchers have discovered.
A former postdoctoral
researcher who worked in the lab of a promising stem
cell biologist engaged in scientific misconduct, faking images and other data in two papers that were later retracted, according to U.S. government investigators.
«The study of this type of tumours has been problematic up to now due to the lack of
cell models and the appropriate animal models,» says CNIC
researcher Juan Carlos Ramírez,
who adds that the difficulty of generating these chromosomal translocations had limited the availability of
cells with this mark of the disease.
Researchers who plan to do a lot of single -
cell RNA analysis can even buy complete systems for it right off the shelf.
[Chinedu Nwokoro et al., «Inhaled black carbon in the lower airways of London cyclists»]
Researchers at the London School of Medicine collected sputum samples from healthy non-smokers
who walk or bike to see how much black carbon was in airway macrophages — a type of white blood
cell that takes in foreign material.
Underscoring the relevance to humans, the
researchers studied nasal and bronchial
cells from people
who suffer from asthma or chronic rhinosinusitis (nasal congestion / sniffles) due to dust - mite sensitivity, and found that on average these
cells had a markedly lower expression of the dectin - 1 gene.
Unlike humans,
who use their lymphatic systems to produce and transport white blood
cells, tuna use theirs to move two of their fins,
researchers report today in Science.
The
researchers used mice with skin like that of red - haired, fair - skinned people,
who don't tan because of a nonfunctioning protein on the surface of the skin
cells that make melanin.
«Most
researchers have relied on
cell lines to screen the effect of drugs and other treatments including viruses,» said Dr. Cripe,
who also is a professor at The Ohio State University College of Medicine.
Today, a team of
researchers at Cold Spring Harbor Laboratory reports in the journal Genes & Development that they have arrived at «new insights into signaling events that underlie metastasis in ovarian cancer
cells,» says Gaofeng Fan, Ph.D., postdoctoral investigator
who conducted most of the experiments, in the laboratory of his mentor, CSHL Professor Nicholas K. Tonks.
The sensor was developed by
researchers at the Georgia Institute of Technology,
who have demonstrated several applications for its ability to spatially resolve the chemical's presence inside
cells.
New Scientist was unable to reach the Lisbon team members, but Jean Peduzzi - Nelson, a stem
cell researcher at Wayne State University in Detroit, Michigan,
who advised the team on their surgical technique — she had previously tested it on rodents — claims the clinic has given the therapy to about 140 people in total.
«It is sobering,» says George Daley, a stem
cell researcher at Harvard Medical School
who has helped write guidelines for people considering stem
cell treatments.
That message, delivered in two studies published today, is both good news and bad news for
researchers who hope to use so - called induced pluripotent stem
cells (iPS
cells) to study diseases and perhaps some day treat patients.
Researchers sequenced ancient DNA from the mitochondria — tiny energy factories inside
cells — from a Neandertal
who lived about 100,000 years ago in southwest Germany.
In 1997,
researchers at Sunnybrook Health Sciences Centre in Toronto combed through nearly 27,000
cell phone calls during a 14 - month period made by hundreds of drivers
who had been in crashes.
The
researchers then studied DNA from the white blood
cells of eight people
who scored in the top 15th percentile of loneliness and six
who scored in the bottom 15th percentile.
And it suggests that stem
cells derived from embryos should remain the primary reference for iPS
cells when
researchers want to compare how
cells from diseased patients behave, says Nissim Benvenisty of Hebrew University of Jerusalem,
who has studied differences between ES
cells and iPS
cells derived from carriers of fragile X syndrome.
This puts control of curli fiber production in the hands of the
researchers,
who can adjust the amount of AHL in the
cells» environment.
In May
researchers at McGill University reported that the gene responsible for creating
cells» protein - building machinery is more frequently methylated in the hippocampus — the brain region responsible for short - term memory and spatial navigation — of depressed suicide victims
who suffered child abuse than in the brains of nonsuicide victims
who were not abused.
This protective effect seems to suggest that infections earlier in life may stimulate the immune system to deal with future infections and cancerous
cells more efficiently, say the British
researchers who made the discovery.
The
researchers,
who report their work in the 26 October issue of Molecular
Cell, hope to soon create an altered version of the protein that will work in humans.
Those hoping for quick clinical success should remember it takes time for revolutionary treatments to go from lab bench to bedside, says Andras Nagy, a stem
cell researcher at Mount Sinai Hospital's Lunenfeld — Tanenbaum Research Institute in Toronto,
who has not been directly involved in Yamanaka's work.
«The
cells of warm - blooded organisms need a mainly constant temperature and tolerate deviations from the optimal 37 ° C only conditionally,» explains Dr. Marco Preußner,
who is a postdoctoral
researcher and first author of the study.
Now, we may know what could have been at the root of the issue, thanks to work by
researchers who attempted to reproduce the results of «observations that may have misled the
researchers who made the original claims -LSB-, which include]
cells that glow, faintly, under key wavelengths of light,» Vogel wrote.
«With this important advance, super-resolution microscopy and DNA - PAINT could become more accessible to biomedical
researchers, accelerating our insights into the function of individual molecules and the processes they control within
cells,» said Wyss Institute Founding Director Donald Ingber, M.D., Ph.D.,
who is also the Judah Folkman Professor of Vascular Biology at HMS and the Vascular Biology Program at Boston Children's Hospital, as well as Professor of Bioengineering at SEAS.
A multicenter team of
researchers reports that a full genomic analysis of tumor samples from a small number of people
who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer
cells.
«We can communicate with
cells much more effectively, and vice versa,» said the study's first author Jameson Rogers, a graduate
researcher at the Wyss Institute
who is pursuing his Ph.D. in Engineering Sciences from Harvard University.
The
researchers collected dermal papilla
cells from seven volunteers
who had been diagnosed with male - pattern baldness.
One of the last
researchers to go through the two - stage approval process was Shinya Yamanaka, the Kyoto University
researcher who first reported the derivation of iPS
cells.