Not exact matches
«The new Park Nanoscience Center at SUNY Polytechnic Institute provides researchers with greater access to Park Systems» cutting - edge AFM nanoscopic tools, featuring reliable and repeatable high -
resolution imaging of nanoscale
cell structures in any environment without damage to the sample.»
The field of live -
cell imaging has expanded greatly in recent years, but still faces many challenges, such as how to improve spatial and temporal
resolution as well as how to keep
cells healthy for extended periods of time.
Previously, high -
resolution live
imaging has been done with
cells cultured on glass slides, which flattens samples.
Earlier, for his Ph.D., he used his physics training to study biological interactions at the molecular
resolution — but for his postdoc he changed approaches dramatically, turning to
cell biology and applying his skills to the development of high -
resolution functional
imaging of DNA transcription in living
cells.
Because SR - STORM gives full spectral and spatial information for each molecule, the technology opens the door to high -
resolution imaging of multiple components and local chemical environments, such as pH variations, inside a
cell.
This method has already been used successfully to reach a maximum
resolution in the
imaging of
cells.
To determine the most common type of age - related segregation errors, the researchers first used a novel high
resolution imaging technique to visualize chromosomes in live mouse egg
cells throughout the whole first stage of meiosis.
His work involves high -
resolution imaging of chick embryonic tissue slices to study the
cell - biological mechanisms driving neurogenesis in the spinal cord, for which Dr. Das played an instrumental role in pioneering new
imaging technology.
But several new
imaging techniques at a range of
resolutions provide new views — and new understanding — of how
cells function.
learn from our speakers the benefits of
imaging live
cells using techniques such as high
resolution microscopy, superresolution microscopy, and high - content analysis
Building on traditional SIM technology, the iSIM allows real - time, 3 - D super
resolution imaging of small, rapidly moving structures — such as individual blood
cells moving through a live zebrafish embryo.
This kind of
imaging is impossible with other microscopes; the ones that are fast enough to record rapid movement do not have a high enough
resolution to see inside the
cells; and other microscopes with similar
resolution are just too slow to capture that amount of motion clearly.
The significance of the team's approach is that it «enables
imaging of live
cells in a high - throughput manner at a time
resolution at which all biologically relevant dynamics appear static,» he said.
Exploratorium, San Francisco Study live specimens, like mouse stem
cells as they progress toward becoming beating heart
cells, at the high -
resolution Microscope
Imaging Station.
The new methods dramatically improve on the spatial
resolution provided by structured illumination microscopy, one of the best
imaging methods for seeing inside living
cells.
Invaluable as markers for monitoring photosynthesis and other energy - related processes in living
cells, green fluorescent proteins (GFPs), discovered in a species of jellyfish, are vital in extremely high -
resolution imaging studies.
In studying the functional behavior of the brain, from control of muscles to the formation of memories, scientists are using such tools such as electron microscopy, recordings of electrical signals from individual brain
cells, and
imaging of brain structures and processes using functional magnetic resonance
imaging (fMRI), positron emission tomography (PET), and high -
resolution optical
imaging.
The researchers used a 2 - photon photolysis technique that can be performed in vivo, together with
imaging, to manipulate and monitor neuronal activity at single -
cell resolution.
The speed, noninvasiveness, and high spatial
resolution of this approach make it a promising tool for in vivo 3D
imaging of fast dynamic processes in
cells and embryos, as shown here in five surrounding examples.
Contact: 508-289-7139;
[email protected] WOODS HOLE, Mass. — Using a simple «mirror trick» and not - so - simple computational analysis, scientists affiliated with the Marine Biological Laboratory (MBL) have considerably improved the speed, efficiency, and
resolution of a light - sheet microscope, with broad applications for enhanced
imaging of live
cells and embryos.
Ueda, Kurihara and their colleagues improved the
resolution of this
imaging technique to be able to observe the internal structure of the
cell.
The High
Resolution Electron Microscopy Facility (HREMF) provides a resource to the scientific community at MD Anderson for high resolution imaging of cells, tissues, organs or polymers containing canc
Resolution Electron Microscopy Facility (HREMF) provides a resource to the scientific community at MD Anderson for high
resolution imaging of cells, tissues, organs or polymers containing canc
resolution imaging of
cells, tissues, organs or polymers containing cancer agents.
The combination of two processes makes this high -
resolution 3D
imaging possible: lattice light - sheet microscopy (LLSM), which images one slice of the
cell at a time, and adaptive optics (AO), which corrects for any blurriness.
But the development of new, high -
resolution imaging technology able to capture single
cells has finally enabled scientists to reliably chart noise at this level, and to study how it influences behavior.
To address this, I am building a microscope and developing analytical tools for high
resolution live -
cell imaging in Archaea - friendly conditions, i.e. 70 - 80ºC, low pH and minimal photo damage.
Combined with spinning confocal, it enables Super
Resolution to be achieved at high speed and low photo - toxicity, making it the ideal solution for live high resoluion
cell imaging.
Several more researchers presented their work during the day, including protein synthesis at atomic
resolution, bio-
imaging opportunities at synchrotrons, multi-dimensional
imaging during plant
cell differentiation, how to use electron cryomicroscopy for in situ structural biology, and how structured illumination microscopy can offer insights into the regulation of mammalian meiosis.
Furthermore, the microscope will be capable of performing live -
cell super-resolution
imaging through structured illumination microscopy (SIM) and Super-Resolution Radial Fluctuations (SRRF); for fixed
cells resolutions on the scale of tens of nanometres will be achievable using single molecule localization microscopy (SMLM) techniques.
Currently, there is no commercial microscopy system available for live
imaging of Archaea with sufficiently high spatio - temporal
resolution to accurately observe processes such as
cell division.
Cell biology has continued to expand ever since, extending its impact on clinical medicine and pharmacology while drawing on new technologies in bioengineering, high -
resolution imaging, massive data handling, and genomic sequencing.
Multiplexed
Imaging Here the goal is to add spatial
resolution to cytometry - data in order to understand, in a tissue, WHERE immune and cancer
cells interact We design, develop and apply methods for multiplexed visualization of protein and RNA molecules in tissue sections.
The Plant
Cell Imaging Center (PCIC) provides researchers at Boyce Thompson Institute (BTI), Cornell University, and SUNY Cortland with access to high - resolution fluorescence microscopes, including a confocal microscope with spectral and quantitative imaging capabi
Imaging Center (PCIC) provides researchers at Boyce Thompson Institute (BTI), Cornell University, and SUNY Cortland with access to high -
resolution fluorescence microscopes, including a confocal microscope with spectral and quantitative
imaging capabi
imaging capabilities.
While
imaging captures brain activation during specific tasks and therefore may identify general brain regions that are abnormal in diseases, it does not have that critical
cell - level
resolution.
The Metabolomics & Proteomics Technology Unit will offer localizomics approaches based on MS
Imaging on tissue / organs slices (or on in - vitro
cell cultures), either in targeted MS (i.e. drug and metabolites distribution) or in untargeted high
resolution (HR) MS (metabolite profiling).