Sentences with phrase «cell response contribute»

Not exact matches

While abnormal immune responses are largely responsible for these diseases, issues relating to gut microbiome, intestinal epithelial cells, immune components and the gut's rhythmic peristalsis motions can also contribute to and exacerbate symptoms.

They focused on the role of monocytes, immune cells that normally pass along the blood vessels and in response to a local infection move quickly into the affected organ and contribute to the localized immune defense there.

Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular «off» switch for the inflammatory immune response that contributes to lung - constricting asthma attacks.

The release of several signals by skin cells that are dying contributes to the creation and spreading of the chronic immune response and hyper - proliferation and irregular differentiation of epidermis,» says Joan Manils, first author of the study and member of the mentioned department and post-doctorate researcher at the Trinity Biomedical Sciences Institute (Ireland).

Those embryonic cells migrate in the embryo and contribute to tissues involved in the fight - or - flight response, facial development and coloring.

Originally, researchers thought Th2 response had evolved to promote tissue repair; however, in the context of lung virus infections, Th2 cells appear to contribute to the overactive immune responses that endanger patients.

Experiments in cells with an inactivated form of Argonaute — which contributes only to the antiviral and not the gene regulation activity of RNAi — confirmed that they were observing an antiviral RNAi response.

Citation: «Misregulation of an Adaptive Metabolic Response Contributes to the Age - Related Disruption of Lipid Homeostatis in Drosophila» Cell Reports, epub, September 12, 2013.

Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina (MUSC) find.

The spread of cancer cells from the initial site of occurrence (primary site) to other secondary tissues is called metastasis, and contributes to poor or limited response of cancer cells to treatments, which results in death.

Past studies have suggested that this kind of damage is associated with abnormal immune responses in the liver, but very little was known about the molecules and cells that contribute to fibrosis.

In response to injury, these cells proliferate and contribute to scar formation.

Some of these signals are in the form of lipids, which contribute to fine - tuning the immune responses of cells such as macrophages and dendritic cells.

I would like to understand how S. pneumoniae stimulates T cell responses in mice and how those different mechanisms contribute to pulmonary disease.

Altered TUBB3 expression contributes to the epothilone response of mitotic cells.

The human like T cell epitopes may contribute to the delayed, low titer of H7N9 hemagglutination inhibiting antibody responses and diminished seroconversion rates that have been observed in human infections and unadjuvanted H7 HA vaccination clinical trials.

It implies that any residual engagement of the T cell receptor on Th cells would result in anergy and contribute to tolerance rather than allogeneic responses.

However, it was difficult to test this hypothesis experimentally as the cortex is connected to other cellular structures that generally contribute to the cellular force response in cell - mechanical probing.

As fibrin builds up in the brain, it triggers an immune response that leads to the degradation of the nerve cells» myelin sheath, over time contributing to the progression of MS.

«We've always suspected that different cell types are involved in determining how a heart is built,» said GICD Director and senior author Deepak Srivastava, MD. «Our research showed that the signals from cardiac fibroblasts contribute to the different responses of cardiomyocytes.»

Furthermore, by chromatin immunoprecipitation and whole - genome scanning approaches, we show that the chromosome ends of senescent cells directly contribute to the DNA damage response, and that uncapped telomeres directly associate with many, but not all, DNA damage response proteins.

Growing evidence suggests that the cell surface CD39 / CD73 enzyme pair contributes to antitumor responses by catabolizing tumor - suppressing extracellular ATP to tumor - promoting adenosine.

Quinoa also does an excellent job of boosting your antioxidant levels, being high in both manganese and copper, which support a healthy immune response, contribute to fat and carbohydrate metabolism and ensure that red blood cells remain in top condition.

When inflammatory response is triggered, white blood cells produce substances that may contribute to insulin resistance and atherosclerosis.

The high antioxidant content of blueberries contributes many health benefits, such as boosting the production of cytokines, which are small proteins that interact with other cells and help regulate immune responses, promote anti-inflammatory activity, and strengthen cell membranes, among other important functions.

Melanopsin cells in mammals are specialized for measuring ambient illumination, contributing to visual discrimination [8,9], and driving a wide variety of physiological responses including, but not restricted to: synchronization of circadian clocks to light: dark cycles, regulation of pupil size, modulation of sleep and suppression of pineal melatonin production [10 — 14].