Sentences with phrase «cell response using»

This study is the first to selectively target ILCs in the presence of an intact immune system, and these findings suggest that under normal conditions, ILCs play a critical role in dampening the anti-bacterial T - cell response using MHCII.

Not exact matches

We are all born with instincts, which include the inate knowledge to use our bodies... inate fear responses (fight flight or reason) etc.... all incredible knowledge... yet ALL of that knowledge must come from ONE single cell... The information MUST be stroed electrochemically... but how?

Using their personal cell phones, farmers send a free text message to a centralized number and WeFarm's algorithms send out each question to its network of farmers, collate responses and are sent back via free SMS.

Researchers at the European Union Reference Laboratory for alternatives to animal testing developed five different tests that use human blood cells to detect contaminants in drugs that cause a potentially dangerous fever response.

This allowed them to track changes in calcium ion concentrations in the cells around wounds in living tissue (as opposed to the cell cultures used in many previous wound response studies) and to do so with an unprecedented, millisecond precision.

And using cells from someone other than the cancer patient being treated might trigger an immune response against the foreign cells.

An immune response, triggered by foreign neural stem cells, could actually help attack tumors, says Evan Snyder, a stem cell biologist at Sanford Burnham Prebys Medical Discovery Institute in San Diego, California, and one of the early pioneers of the idea of using stem cells to attack tumors.

A drug used to stop immune cells from gobbling up transplanted organs and bone marrow has been caught boosting the immune response to a virus in mice and monkeys.

Lo's team set out to find ways to further weaken the tumors, since the drug addiction response (which can range from a mere slow down of the cancer's growth rate to cancer cell death), can be used to improve clinical outcomes.

Furthermore, the team found that ONA inhibited the pro-tumor functions of myeloid derived suppressor cells (MDSC), which are closely associated with the suppression of the anti-tumor immune response of host lymphocytes, by using preclinical sarcoma model.

Julian Dindas, a PhD student at Hedrich's department, used microelectrodes that register the electric voltage of the root hair's cell membrane, the so - called membrane potential, to study the early responses of the cell to a hormone pulse.

The researchers found that, in response to the maximum tolerated doses of several commonly used chemotherapy drugs, breast cancer - associated fibroblasts secrete large amounts of cell signaling proteins called ELR + chemokines.

Using tiny electrodes, they monitored the response of brain cells responsible for movement.

Using cells from cadavers, doctors have been experimentally transplanting pancreatic islets into humans for decades, but as many as 60 percent of the transplanted islets die immediately because they are cut off from their blood supply and are killed by an immune response due to direct injection into the bloodstream, and those that survive the transplant usually die within several months.

Davis will use his findings to figure out a way to match specific immune cells to vaccine response.

One of the genes Deisseroth uses triggers the cell to fire in response to blue light; another responds to yellow light by suppressing activity in the cell.

Assembling mRNA using pseudouridine, a nucleoside variant that occurs naturally in the body, greatly reduced the tendency of immune sentinels called dendritic cells to shoot out inflammatory molecules in response, they reported in 2005.

An example of associative memory would be if the cell learned a response to one stimulus and could then use that response when faced with a second stimulus that is similar to the first.

According to the researcher, further studies are warranted to confirm responses in primary cells and to reveal whether Rho - kinase inhibition stimuli can be used to manufacture a better cartilage - type of tissue in laboratory.

Building on the newly - published pilot study, the team will conduct experiments using a windtunnel which measures the behaviour of mosquitoes towards odours and electrodes which track the response of individual odour - detecting cells from within the antenna of the mosquito in specially - designed secure laboratories at the School to measure the responses of malaria - infected Anopheles gambiae s.s. females to human odours.

When a standard hearing test was performed on these hearing - impaired individuals, the responses of their auditory sensory cells and neurons, although normal to begin with, gradually worsened as the test went on as a result of the sounds used.

They might be put to use right away to track cultures of immune cells as they migrate in response to chemical stimuli.

The retrograde response pathway is specific to the yeast used in the study and supplies key amino acids to the cell by changing the metabolic process of the mitochondria.

Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina (MUSC) find.

Using a technique that measures the response of the olfactory system to odours, the researchers showed that copper and nickel affect the ability of different cells to detect odours.

But in truth, most (26 of 28 vaccines currently licensed for human use) stimulate primarily a B - cell or antibody response, which in many cases is sufficient.

The team used an imaging technique that allowed them to view the responses of over 100 Kenyon cells at a time and, importantly, quantify their results.

The Stanford researchers, who report their results in the current issue of the Journal of Experimental Medicine, used a clever trick to shut off this damaging immune response: They engineered TH1 cells to produce IL - 4 instead of their normal cytokines.

For the past six years, the Wu laboratory has been investigating how to use immunosuppressive medications to dampen the body's response to both embryonic and induced pluripotent stem cells to render them more amenable for clinical use.

The technique replaces the defective gene response for cystic fibrosis by using inhaled molecules of DNA to deliver a normal working copy of the gene to lung cells.

Using near - infrared light, researchers have shown they can selectively activate an immune response by controlling the flow of calcium ions into the cell.

For example, they can be used as programmable drug carriers, diagnostic devices or to study the response of cells to precisely arranged molecules.

Discuss how mouse models can be used to study human immune responses against leukemia (using primary or genetically modified leukemia cells) and melanoma

He is also developing a robust and comprehensive panel of 3 - D cell culture models from patient - derived primary cells that can be used to characterize different disease phenotypes and investigate the chemo - response of cells to novel or known drugs.

Like other cells, cancer cells boost their production of HSPs in response to stress, but whether they use HSF1 to call the shots wasn't certain.

In a paper published in the journal Proceedings of the National Academy of Sciences, Sangeeta Bhatia of MIT and Charles Rice of Rockefeller University describe using microfabricated cell cultures to sustain hepatitis B virus in human liver cells, allowing them to study immune responses and drug treatments.

If electrical energy can be used to modulate cell response, why not optical energy as well, Boyden asks.

Results from a clinical trial investigating a new T cell receptor (TCR) therapy that uses a person's own immune system to recognize and destroy cancer cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced disease after undergoing autologous stem cell transplants (ASCT).

Rutgers University scientists have discovered the three - dimensional structure of a gene - specific transcription activation complex, providing the first structural and mechanistic description of the process cells use to turn on, or activate, specific genes in response to changes in cell type, developmental state and environment.

SynNotch engineered T cells are also versatile in that they can either be used drive a potent immune response to cancer or suppress an immune response in an autoimmune setting,» he said.

An international research team headed by the rheumatologist Dr Andreas Ramming at Friedrich - Alexander - Universität Erlangen - Nürnberg (FAU) has now managed to identify an immune system cell type that can be used in a targeted attempt to control the inflammatory response in arthritis patients.

Through the use of powerful genomic techniques, researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) have found that the development of immune cells, called innate lymphoid cells (ILCs), gradually prepares these cells for rapid response to infection.

«Vaccine used to treat cervical precancers triggers immune cell response.»

Researchers use a unique, in silico predictive algorithm platform to select neoepitopes, which are similar to neoantigens, that can generate potent and specific T cell responses.

Microbial pathogens induce specific host responses or «RNA biosignatures» that can be identified using microarray analyses of blood leukocytes (white cells).

«These splicing signatures could potentially be used as clinical biomarkers to detect blood stem cells that show signs of early aging or leukemia, and to monitor patient responses to treatment,» said Crews.

The new technique, pioneered by Wilson and fellow researchers at the Emory University School of Medicine in Atlanta, saves time by using antibodies produced by so - called B cells (white blood cells that produce and then ferry them to infection sites to battle invading germs) in response to vaccines instead of to actual infections.

Instead of stirring up powerful T cells through an injected amyloid vaccine, they used a nasal spray containing two drugs that provoke a less robust but more manageable immune response.

Lead author Nigel D'Souza, then a postdoctoral researcher at Lamont, discovered the phytoplankton response to oil seeps while on a ship in the Gulf of Mexico monitoring chlorophyll fluorescence — energy that is emitted as light by compounds inside phytoplankton cells used for photosynthesis.

Because these islets carried the kind of peptide that spleen cells use to reeducate the immune system, they were able both to control blood sugar and to end the autoimmune response.