Sentences with phrase «cell responses during»

Alterations in peripheral blood B cell subsets and dynamics of B cell responses during human schistosomiasis.

A research group from the Department of Biomedicine at the University and the University Children's Hospital of Basel now discovered that innate lymphoid cells become activated and induce specific T and B cell responses during inflammation.

Not exact matches

During a raid, officers with the jail's Direct Action Response Team clear out inmates from sections of the jail, frisk them, and turn over their cells in search of the contraband.

Interestingly, they found that stem cells coming from different epidermal compartments present very similar response during wound repair, despite the fact that they are recruited from different regions of the epidermis.

They found that STAT6 - IP prevented RSV - induced changes to airway cells called alveolar macrophages, which can promote asthma - like responses both during and following viral infections.

Now, a UCLA study has traced the Pavlovian response to a small cluster of brain cells — the same neurons that go awry during Huntington's disease, Parkinson's disease and Tourette's syndrome.

A study has traced the Pavlovian response to a small cluster of brain cells — the same neurons that go awry during Huntington's disease, Parkinson's disease and Tourette's syndrome.

It has been particularly difficult to measure changes in electrical functions of cells grown within Organ Chips that are normally electrically active, such as neuronal cells in the brain or beating heart cells, both during their differentiation and in response to drugs.

«The suggestion here is that IL - 27 normally limits the severity of disease during these viral infections in part by influencing the quality of T - cell responses,» Muallem said.

«Even when they had defective mitochondria, the cells with the retrograde response and AMPK simultaneously activated during growth were able to live as long as cells with normal mitochondrial function.»

During the initial phase, a relatively aggressive inflammation response occurs, and several types of cell from the immune system are attracted to the wound.

A certain cytokine, or small protein that helps cells communicate during immune responses, can control whether immune cells promote or suppress inflammatory bowel disease, a finding that could lead to new treatments, according to a study led by Georgia State University.

During sleep deprivation cells upregulate the UPR — the unfolded protein response — a process where misfolded proteins get refolded or degraded.

«But we discovered that attaching microbeads to the cell's surface amplifies the cell's response during cavitation and produces the same result with much less risk of cellular injury.»

Tanimoto, Yamazoe - Umemoto and colleagues discovered that a tiny roundworm with only 302 nerve cells do «decision - making» during escape response from the aversive odor.

In contrast to necrosis, which is a form of cell death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process that generally confers advantages during an organism's life cycle.

«Taken together, these studies show that the NK cell IL - 10 response is associated with extensive proliferation, either under in vitro conditions independent of infection, or in vivo during infection,» wrote the authors, including co-lead author and former Brown postdoctoral researcher Seung - Hwan Lee, who is now at the University of Ottawa.

The Tfh cell response to vaccination is greatest during the first trimester of pregnancy.

In response to hormones circulating during pregnancy, DNA in mammary gland cells loses certain marks called methyl groups, the team found.

And during the Skylab missions, which began in 1973, scientists saw decreased white - blood - cell responses in returning astronauts.

In the study to be presented, researchers found that the T - follicular helper cell response to vaccination is greatest during the first trimester of pregnancy.

Using bioinformatics tools to identify and map out specific components and regulatory interconnections, the study team found highly dynamic activities during CD8 + T cell responses: a distinct repertoire of super enhancers — groups of enhancers that interact with promoters to drive gene transcription, new groups of enhancers that jump into activity only in the memory cell stage, and extensive re-wiring of regulatory circuits from one cell stage to another.

While the observed differences of the individual steps were mostly modest, mathematical modeling suggested that even small delays in the trafficking of these immune cells will lead to reduced initiation of a WNV - specific antibody - response during the early stages after infection.

In the case of planarians, the gene egr - 4 seems to perform an early control of cell proliferation as a response to amputation, and be involved later in the early differentiation of brain during regeneration.

During inflammatory responses due to infection, trauma, or cancer, the body's immune system becomes highly activated in an attempt to fend off invading organisms, foreign bodies, or tumor cells.

The force of that blood flow helps keep the cells that line the blood vessels, called endothelial cells, healthy; when blood flow is disrupted, such as during surgical procedures or a stroke, the vessels start to leak, which can cause a host of inflammatory responses that lead to cell damage and disease.

In healthy individuals, MDSCs regulate immune responses and tissue repair, and the population of these cells rapidly expands during inflammation, infection and cancer.

However, researchers are still learning how best to implement immunotherapy regimens, making monitoring of the immune response during treatment development and implementation critical to predicting how the modified cells will function, and how the immune system as a whole will react.

Studies by Shibo Jiang at Fudan University in Shanghai, China, and colleagues have found that the bit of the viral surface protein that attaches to a cell during infection — the binding site — only induces the right kind of antibody response.

The healthy pancreas can at times boost its production of β cells, both in response to injury and to increased demand for insulin — for example, during pregnancy.

In addition, the strain isolated from lions and hyenas during the 1993/1994 epidemic had rare mutations in two viral proteins: the CDV - H protein, which binds to the host cell receptor (called SLAM CD 150) and therefore plays an important role to facilitate viral entry into host cells, and the CDV - V protein, which enables the virus to manipulate the innate immune response of the host.

After the first MVA.HIVconsv vaccination, HIVconsv - specific T cell responses raised to a median peak magnitude of 965 IFNg SFC / 10E6 (range 400 - 3,340, in cryopreserved - and - thawed PBMC), which was significantly higher (p = 0.0353) than peak responses during BCN01.

The new method, published today in the journal Nature Biotechnology, has implications for better understanding how different groups of cells change during disease progression, in response to drug treatment, or across evolution.

(C) Average response of an example cell during RF mapping.

We notably follow the time course of structural changes in response to cues that affect gene expression either transiently or permanently: changes in genome structure during transient hormonal response of differentiated cells and stable trans - differentiation of B cells to macrophages.

Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells.

In addition to p53, there are other transcriptional activatory mechanisms that are not well understood for the most part and which operate in response to mitogenic stimulation (11, 12), transforming growth factor - β (13, 14, 15), and aberrant oncogenic signals (16, 17) or during a number of cell differentiation processes (18, 19).

Caffeoylxanthiazonoside exerts cardioprotective effects during chronic heart failure via inhibition of inflammatory responses in cardiac cells.

By integrating the sequence data and the associated metadata, we have established laboratory and bioinformatics - based methods that enable us to investigate scientific questions including: the tropism of ZIKV for dendritic cells and the antiviral response of the cells during infection (Bowen et al. 2017); investigating the phylogenetic diversity of strains obtained by Biodefense and Emerging Infections (BEI) Resources and distributed to virologists (manuscript in preparation); the genetic determinants of ZIKV host adaptation in C6 / 36 mosquito vs. Vero cells; and the diversity of ZIKV circulating in limited geographic regions, including Barbados, Colombia, and the state of Chiapas, Mexico.

During the stress response that occurs as a cell becomes cancerous, and in response to chemotherapy, p53 attempts to repair DNA damage that has occurred, and, if not successful, p53 orders the cell to die.

She gained expertise in human immunology during her post-doctoral training at Blood System Research Institute while working on T cell responses to West Nile virus (WNV) in blood donors.

Post-translational modifications of proteins are important for activation of T cells during an immune response.

We applied this to the single - cell RNA - seq data of the immune cells in our study, to learn about the bifurcation of cell types happening during the malaria immune response.

E and F - the time responses of PNBs in C4 - 2B cell obtained during the first and the second scans.

the dynamics of stress response in individual yeast cells during aging.

A head - tracking response is observed in the dystrophic RCS rat during optokinetic testing of the left eye, 13 weeks after iPS - RPE cell transplantation.

p53 not only down regulates cell division during the normal process of aging and senescence, but it is also involved in a response to DNA damage [27,28] and telomere shortening [29].

These observations demonstrate that with a pregnancy preexisting premalignant mammary cells overcome both the apoptotic response to an oncoprotein and the robust cell death at involution, which normally clears the large mass of cells gained during pregnancy / lactation.

Induction of IL17 following S. aureus bioparticle challenge was compromised in mice lacking the ASC (Apoptosis - associated speck - like protein containing a CARD) inflammasome subunit (Figure 1G), consistent with a role for IL1β in activating IL7RαhiCcr6 + cells during the response to these bacteria.

That basically means the compounds in Elder have the ability to raise and lower cytokine production in your body so that your cells are better able to communicate during an immune response.