Not exact matches
Even after initial purification of the
sample, liquid biopsies typically
contain much more nucleic acid from healthy
cells than from tumors.
The diagnosis of cancer and study of disease progression is often accomplished by examining a tumor
sample containing many billions or even trillions of
cells.
But the
samples he saw never
contained intact organelles — specialized
cell structures with dedicated jobs.
Five days later the team found all
samples contained more
cells than before, but treated ones had between 36 and 90 per cent fewer
cells than untreated
samples.
This is normally used to detect fetal abnormalities such as Down's syndrome, and involves inserting a needle into a pregnant woman's belly to take a
sample of amniotic fluid
containing cells from her fetus.
For spectroscopic applications, this type of coherent light source can pass through a
sample cell containing unknown gases.
After a four - year experiment with two comparable 533 - tonne
samples of municipal waste, the leachate from the wet
cell contained dissolved organic particles from food, leaves and garden debris totalling 2700 milligrams per litre.
Then they collected the fluid that those Fam20C - deficient cancer
cells and non-manipulated cancer
cells were grown in and analyzed the proteins each
sample contained.
None of the
samples in the study
contained microbial species or
cells concentrations that present a public health risk.
Nearly half of the
samples contained cells with flagella, tail - like projections that sperm use to swim.
The kit
contains human
cells and DNA extracted from them, along with the results of various tests carried out on the
samples by a group of molecular biologists.
Because any
sample of cancer
cells is likely to
contain thousands of mutations, advanced analytic tools are needed to distinguish harmless «passenger» mutations from the dangerous mutations driving the disease.
Once they had established the chemical and physical details about the nanocrystals, the team then tested the particles as «staining» agents on a tissue
sample containing liver cancer
cells held on a microscope slide.
They found that human blood
samples contained T
cells specific for all 20 versions of the virus.
For the new study, described in the October 23rd issue of Nature Communications, scientists at the Johns Hopkins Kimmel Cancer Center and Dana Farber Cancer Institute in Boston collected tissue
samples containing normal
cells, ovarian cancers, metastases that had spread elsewhere, and small cancers found in the fallopian tubes, which included single
cell layers of cancer called «p53 signatures» and serous tubal intraepithelial carcinoma, or STIC lesions.
To confirm that the missing mutations were important for generating an immune response, the researchers cultured a subset of the neoantigen protein fragments
containing the tumor mutations with immune
cells taken from three patients» blood
samples.
But locating the
cells that
contain the 50 - nanometer particles has been like looking for a needle in a haystack, in part because the tissue - dissolving methods used to identify magnetite turn biological
samples to mush.
When the girl's mother was pregnant, doctors
sampled the chorionic villus, part of the embryonic side of the placenta, and found that the
cells contained three copies of chromosome 15.
To measure the pH of our
samples, we used a solution of
cell culture medium, which is buffered and
contains the pH indicator phenol red.
When the skin
cell sample is taken from someone with a specific disease, those iPS
cells contain a complete set of the genes associated with the illness, and disease models can be developed to facilitate research and drug discovery.
Scientists looked at tumour
samples and found that the drug penetrates the core of the tumour as well as the surrounding areas which
contain smaller numbers of cancerous
cells.
This means that, where appropriate, consent and ethical approval must be obtained from research participants before using their
samples, and ethical approval from the National Research Ethics Service (NRES) must be obtained for the storage and use of material that
contains human
cells (defined in the Act as «relevant material»), at the Sanger Institute.
Kelley, lead investigator on the study published today in Nature Chemistry, explained how her team has advanced a completely new approach using magnetic nanoparticles with DNA capture probes on their surface that can target circulating tumour
cells (CTCs) in blood
samples to see if the
cells contains biomarkers associated with drug resistance.
For negative control data where each droplet
contains RNA from the same solution, the count depth variability must be technical, but in real
samples this could also be due to
cells having variable amounts of RNA.
As medical testing and citizen - or patient - driven genomics become less expensive and more available to the general public, some people are scraping their cheeks for
cells, spitting the saliva
containing their DNA into test tubes, and then shipping the
samples to laboratories for testing.
The probe
contains Martian soil
samples from which British exobiologist Hugh Derry (Ariyon Bakare) is able to isolate a single -
celled organism, which he aims to bring back to life.
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Contains: 18 individualized profile sheets, Background information on NSA surveillance, Graphic organizer for assigned roles, Graphic organizer with word - for - word format on how to run committee meetings and floor debate,
Sample rubrics for 3 - minute speeches and participation, Socratic seminar questions for students observing speeches / committee hearings, Maps to various educational standards,
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Then there's the Frozen Ark Project working to save
samples of frozen
cells containing DNA from endangered animals before they go extinct.
A
sample of the ear discharge may then be viewed under a microscope to determine if it
contains bacteria, white blood
cells, yeast, fungi, ear mites or ear mite eggs.