The Sanford Consortium for Regenerative Medicine facility is intended to house biologists, chemists, technologists, bioengineers, computer scientists and clinicians in open laboratories and is designed to facilitate and encourage collaboration among them as required to translate the basic understanding of stem
cell science into tools useful to diagnose and treat human disease.
Organized by the Alliance for Regenerative Medicine (ARM), the California Institute for Regenerative Medicine (CIRM), and the Sanford Consortium for Regenerative Medicine, the 2013 Stem Cell Meeting on the Mesa is a three - day conference aimed at bringing together senior members of the regenerative medicine industry with the scientific research community to advance stem
cell science into cures.
CIRM leaders have said that the organization is now entering a second stage in which the focus of its funding will shift to translating basic stem
cell science into therapies.
Not exact matches
In his book The
Science of Hitting, Ted explains that he carved the strike zone
into 77
cells, each the size of a baseball.
Science has inserted a synthetic copy of DNA
into a living
cell membrane.
Whether it is changing text books to teach religion as a «
science,» making laws that prohibit stem -
cell research which would without question help those in need, to stopping of any kind of gay rights, trying to put religion (christianity)
into schools, a woman's right to choose, etc, etc...
It is only by a leap of
science - fiction (the kind exemplified by Teilhard de Chardin's «psychical dust» and subsequent «complexification» theory) that psychicalized
cells can be transformed
into my awareness of myself.
Elsewhere, Philip Ball, an English
science writer, reports on research
into the mechanical properties of cancer
cells.
Its nice to see people using their
science books, and Pedro its nice to see you've read some
science as well as religious books, I would just like to say that no one has actually figured out how the first
cell came
into existence billions of years ago.
If religious right didn't intrude
into government... meddle in
science (hobbling stem
cell research.
Jiachen Lee, Arooba Ahmed and Jillian Parker, a trio of young scientists from the Half Hollow Hills school district won the $ 100,000 top team award in the prestigious Siemens Competition in Math,
Science & Technology for their research
into cell division that could help find treatments to cancers, viruses and other diseases.
Treating the skin
cells with a biochemical cocktail to promote neural stem
cell characteristics seemed to do the trick, turning it
into a one - step process, he and his colleague report today in
Science Translational Medicine.
Now, in a study published February 13 in
Science Signaling, Lin's team discovered that a chemical compound that activates ATF6 also converts patient - derived stem
cells into blood vessels.
In this special section of
Science, expert contributors retrace the long and tortuous path leading to the mapping and identification of the BRCA1 gene; discuss the ways in which BRCA mutation status has been integrated
into the clinical management of patients in high - risk families; and highlight the role of the BRCA proteins in preserving the structural and numerical integrity of chromosomes throughout the
cell cycle, a function that may explain their tumor suppressor activity.
Adenovirus 36 has been found to encourage the transformation of adult stem
cells in fatty tissue
into fat
cells as discussed on the daily Scientific American podcast 60 - Second
Science on August 20th.
The paper's lead author — Marcus Yip, who completed his PhD at MIT last fall — and his colleagues Rui Jin and Nathan Ickes, both in MIT's Department of Electrical Engineering and Computer
Science, will also exhibit a prototype charger that plugs
into an ordinary
cell phone and can recharge the signal - processing chip in roughly two minutes.
This week in
Science Advances, he offers one answer: a fuel
cell that generates electricity while converting carbon dioxide
into a commodity chemical.
Its impact appears to reduce the ability of the
cells in the eye's trabecular meshwork to continually move the clear aqueous humor out of the front of the eye and dump it
into the body's general circulation, said Liu, corresponding author of the study in the journal Investigative Ophthalmology & Visual
Science.
Nevertheless,» [the] study is very important because it demonstrates for the first time that we can use gene therapy to transform
cells in the brain
into ones that will secrete GDNF,» says Jeffrey Kordower, a professor of neurological
sciences at Rush Presbyterian Medical Center in Chicago.
The drugs block viral entry
into cells, the team reports in the June 3
Science Translational Medicine.
In their report published in
Science Immunology they describe how expression of a specific molecule — complement C5a — is required to cause the immune
cells called neutrophils to adhere to joint surfaces and migrate
into the joint, a process known to set off the inflammatory cascade.
In the study published in the journal
Science Signaling, the team led by LLuís Espinosa, investigator of IMIM's research group
into stem
cells and cancer, have shown that inhibition of endosomal activity is a potential therapeutic strategy for the treatment of cancers with the BRAF mutated gene.
However, only rigorous
science and responsible regulation can ensure the safe and effective translation of
science into effective therapies,» remarked Paolo Bianco, Pathologist, Stem
Cell Biologist, Professor of Pathology at the University of Roma «La Sapienza» and one of the 13 authors of the commentary who come from Italy, Germany, the United Kingdom, The Netherlands and the United States.
«The long - term vision is simple,» said Saif, who is also part of the Beckman Institute for Advanced
Science and Technology at the U. of I. «Could we make elementary structures and seed them with stem
cells that would differentiate
into smart structures to deliver drugs, perform minimally invasive surgery or target cancer?»
The lab, at times, feels like a seething primordial soup of Darwinian selection, where only the strongest survive (i.e., publish papers in
Science,
Cell, or Nature), and the weak fade
into oblivion (i.e., become anorexic, turn
into technical sales reps, or go to law school).
A major breakthrough occurred last year when scientists figured out how to turn skin
cells into ES - like
cells that could serve the same purpose (
Science, 23 November 2007, p. 1224).
«Compared to any other device that converts chemical energy
into electricity, the fuel
cell, and in particular the solid oxide or ceramic fuel
cell, is hands down the most efficient,» says veteran fuel
cell researcher Eric Wachsman, director of the University of Maryland Energy Research Center, who published research pointing the way to lower temperature SOFCs on November 18 in
Science.
In the online edition of
Science, he and his colleagues report that Oct4 and Sox2 were capable of converting neonatal foreskin fibroblasts
into cells similar to Yamanaka's, whereas Nanog significantly boosted the frequency of reprogramming and Lin28 upped it by a moderate amount.
This idea turns
science into production and employs a cascade of thousands of tiny robotic
cells.
Science tells us that Earth's first single -
celled organisms emerged about 3.5 billion years ago and only gradually evolved
into many different species, he explained.
In a study spanning molecular genetics, stem
cells and the
sciences of both brain and behavior, researchers at University of California San Diego, with colleagues at the Salk Institute of Biological Studies and elsewhere, have created a neurodevelopmental model of a rare genetic disorder that may provide new insights
into the underlying neurobiology of the human social brain.
But additional research presented at the meeting may boost their efficiency: teams from Tokyo University of
Science and Notre Dame both revealed new types of dyes that could extend the spectrum of light captured by such
cells into the infrared range.
Using a process called somatic
cell nuclear transfer (SCNT), a team from Oregon Health &
Science University (O.H.S.U.) in Portland implanted the contents of individual skin
cells from adult male rhesus macaques
into each of 304 macaque egg
cells stripped of their genetic material.
«This information yields new insights
into how sperm stem
cells function and develop under normal circumstances,» says the study's lead author Bradley Cairns, PhD, senior director of basic
science at HCI and professor and chair of oncological
sciences at the U of U. «We have built a very important framework we can now use to help us understand what happens when things go wrong, resulting in issues like infertility and cancer in men.»
Research conducted at Japan's National Institute for Materials
Science built on previous findings that gold nanoparticles can encourage stem
cells in the bone marrow to differentiate
into bone
cells, and that specific biomolecules can inhibit or promote stem
cell differentiation.
Now, a collaboration between the RIKEN Center for Integrative Medical
Science (IMS) and other institutions in Japan and Europe have found that in immune
cells, simply blocking a transcription factor that leads to differentiation is sufficient to keep
cells in a multipotent stem
cell - like state where they can continue to proliferate and can later differentiate
into various
cell types.
The new finding brings a measure of closure to a story that first rocked the
science world in February 2004, when Hwang and colleagues at Seoul National University announced they had cloned a female donor's
cell by transferring its nucleus
into one of her egg
cells stripped of its nucleus in a procedure known as somatic
cell nuclear transfer (SCNT), and harvested embryonic stem
cells from the resulting fusion.
Four weeks after transplanting these
cells into the kidney cavities of mice with a form of kidney anaemia, the treated animals had blood EPO levels 20 times higher than those in controls (
Science Translational Medicine, doi.org/cdmx).
When these
cells were coaxed
into forming sperm and used to fertilise eggs, 50 to 60 per cent of the resulting pregnancies led to live births (
Science, doi.org/cbxt).
Developmental biologist Goro Yoshizaki of Tokyo University of Marine
Science and Technology in Japan and his colleagues set out to see whether spermatogonia — male germ
cells that give rise to sperm — might contain a subpopulation of
cells with stem
cell - like activity that can develop
into either sperm or eggs.
Converting adult skin
cells into pluripotent
cells — immature stem
cells that can be programmed to become any tissue in the body — is a rapidly developing area of
science that earned the researcher who discovered the technique, Shinya Yamanaka, a Nobel Prize in 2012.
Specialization in at least three of seven possible focus areas (biochemistry and
cell biology, genetics, medical biology, microbiology, ecology, plant
sciences, zoology / animal
sciences), with the option to develop a focus area
into a primary focus.
LOCATING PRE-HEMATOPOIETIC STEM
CELLS Researcher: Fuchou Tang, Assistant Professor, Biodynamic Optical Imaging Center, Integrated Science Research Center, Peking University Project: In a study published in Nature, Tang and his collaborators isolated pre-hematopoietic stem cells (HSCs) for the first time and showed their unique transcriptome signatures before and during their maturation into HSCs (533:487 - 92, 2
CELLS Researcher: Fuchou Tang, Assistant Professor, Biodynamic Optical Imaging Center, Integrated
Science Research Center, Peking University Project: In a study published in Nature, Tang and his collaborators isolated pre-hematopoietic stem
cells (HSCs) for the first time and showed their unique transcriptome signatures before and during their maturation into HSCs (533:487 - 92, 2
cells (HSCs) for the first time and showed their unique transcriptome signatures before and during their maturation
into HSCs (533:487 - 92, 2016).
Over the years, Dr. Nimer has conducted extensive clinical and basic
science research
into the treatment and genetic basis of adult leukemia and bone marrow failure states, defining the regulatory mechanisms that control the production of blood
cells and exploring ways to improve the treatment of blood based cancers.
I think a lot of people were led to believe — and to what extent scientists were responsible for this is an interesting question — that if only the regulations were relaxed, embryonic stem -
cell science would be central to our medical research and practice going
into the future, and that it would massively alleviate suffering and produce cures for dreaded diseases.
iPSCs — stem
cells created from skin
cells that can be transformed
into any type of
cell in the body — revolutionized biomedical
science.
In an emphatic letter published today in
Science, 11 researchers argue that NIH should reverse its decision against funding studies in which scientists implant human stem
cells into early, nonhuman embryos.
BioRN is a life
science research and industry cluster dedicated to the development of
cell - specific, molecular and personalised innovative treatments The BioRN Cluster aims at promoting the region
into one of the top life
science clusters in Europe.
This is the first clinical trial of its kind and The Human Trial is the first film to take us backstage
into the world of cure research: the formidable obstacles and grinding effort, the complexity of the disease and the
science, what it takes to harvest
cells, regulatory rules and the $ 5 billion plus it typically takes to bring a drug to market.
«This is important biotechnologically, because if you look at if from the angle of genome editing, the delivery of small genes
into cells is much easier than the delivery of large genes,» said Rotem Sorek of the Weizmann Institute of
Science in Israel who was not involved in the work.