Seven patients underwent a
blood cell selection process (apheresis) to harvest a certain population of their white blood cells.
However, because IFN - γ is widely known to influence several endothelial properties, such as junctional integrity (21) and adhesion molecule expression (22), we elected to remove this cytokine from cultures immediately after the second session
of cell selection.
However, Vα14
iNKT cell selection is dependent upon expression of CD1d, a MHC class I - like protein that presents lipids rather than peptides, by other DP thymocytes.
Cells grown with this culture system are maintained in an undifferentiated state with virtually no detectable background differentiation, eliminating the need
for cell selection.
Immunotherapeutic strategies are rapidly evolving, and recent advancements
in cell selection and gene editing have reshaped the reality of immunotherapy.
Identify immune cell populations with our flow cytometry antibodies and kits and isolate them with
our cell selection kits.
R&D Systems has since established itself as a developer and manufacturer of high - quality proteins and the world leader in immunoassays as well as a producer of antibodies, arrays, stem cell products,
cell selection and detection products among other cell biology tools.