Sentences with phrase «cell shape»

Those analyses have long relied on qualitative changes in cell shape to track physiological shifts.

Understanding this material stiffness is therefore pivotal for our understanding of cell shape changes.

This forced movement of water changes vaginal cell shape and biology, leading to irritation, tissue damage and disruptions of the vaginal ecosystem.

With a cell - by - cell assessment of gene activity they are monitoring how precursor cells shape and organize themselves into something loosely resembling a functioning liver.

Machine learning combined with molecular paints allows rapid screening of changes in cell shape and function.

This provides a wealth of information on the patterns of cell shape, motion and division.

Inside epithelial cells, E-cadherin molecules are anchored to the cell cytoskeleton, which controls cell shape and plasticity.

But patients with sickle cell disease have stiff, sticky red blood cells shaped like crescents that do not easily flow to vital limbs and organs.

«The degree to which our discoveries linked interacting systems and provided clear explanations for cell shape control was great.

«This collaboration enabled us to learn more about what really controls plant cell shape in one year than we had in the previous 10,» said Daniel Szymanski, Purdue professor of botany and plant pathology and leader of the research team.

Such a leap «is not trivial,» says Christine Jacobs - Wagner, a microbiologist at Yale University who also studies bacterial cell shape.

The field's clinical cousins — pathology and hematology — also rely heavily on cell shape.

«We have already demonstrated that microgravity affects cell shape and behavior,» said Nielsen.

Dr Sánchez - Corrales» search for an adequate mathematical representation for cell shape led the group to discover there were inherent errors in quantifying shape properties through a traditional method named the Elliptic Fourier Analysis, named after Joseph Fourier the French mathematician and physicist.

The team used a combination of experimental data from live plant cells and computational modeling to gain new insights into how plant cytoskeletons — intricate networks of protein fibers and tubes within cells — cooperate to produce complex cell shapes.

Normally, tau proteins help to stabilize the hollow tubes called microtubules that help give cells their shape.

Analyzing the ellipsoid collection allowed them to categorize average cell shapes by scaffold.

«Due to the nature of how a cell nestles among its immediate neighbors, a scientist can now look at cell shapes and make a reasonable guess as to why, and how fast, those cells will migrate, remodel, or invade surrounding tissues.»

Mechanics and regulation of cell shape during the cell cycle.

Our insight will substantially enhance our understanding of dynamic cell shape regulation for instance in the context of cell migration as in cancer metastasis or during morphogenesis.

Anja (McGill University, Quebec, Canada) is world - renowned for her work in the cell biology of the pollen tube, work that addresses biomechanical aspects, such as how cell shape is determined, and how materials are secreted appropriately to direct cell growth.

A combination of circumstances induced me to leave India and enroll in the graduate program in what was then the department of cellular and developmental biology at the University of Arizona, Tucson, in the U.S. My Ph.D. supervisor, Neil Mendelson, had been a well - known name in DNA replication and cell division in Bacillus subtilis, but by the time I had joined his lab, his interest had decidedly shifted to cell shape determination.

Besides devising unique ways to analyze conventional cell images, researchers are also using new microscopy techniques to better define cell shapes.

From this collaboration the teams developed the LOCO - EFA technique which involves decomposing two - dimensional cell shapes — the shapes you can see under a microscope — into a series of ellipses.

Intravital two - photon bone imaging is superior compared with conventional analyses of the shape and form of a tissue because it enables two - dimensional scanning in bone in a focal plane to observe cell shapes and the appearance of mOBs and mOCs in the body.

Chen's team found that rounded cells had less active Rho than stretched cells, suggesting that cell shape determines cell fate by turning Rho on or off.

Microtubules have become familiar elements in the frameworks that organize cell shape and cell division.

The gene discovered in the research couples the exocytosis - regulating protein Sec10 with formin, a protein that regulates the remodeling of the actin cytoskeleton critical to forming cell shapes.

The study, «Loss of miR - 203 regulates cell shape and matrix adhesion through ROBO1 / Rac / FAK in response to stiffness» by Lily Thao - Nhi Le and colleagues, identifies a signaling pathway that may protect breast cells from the tumorigenic effects of stiff extracellular matrices.

The previously unknown nerve cell shape is now presented in the journal Neuron by a research team from Heidelberg, Mannheim and Bonn.

So, we decided to measure cell shape and see how that changes, if it becomes more 3D in the scaffold.»

«Bio scaffolds categorized by characteristic cell shapes.»

Cell shapes became progressively less elongated and less variable as they jammed, and more elongated and more variable as they unjammed.

The first observation of correlation between isotropic growth and puzzle - like cell shape came from the Roeder Lab (Cornell University) and was then explored in collaboration with the Smith Lab (Max Planck Institute for Plant Breeding Research).

The Hamant Lab (ENS de Lyon) provided experimental evidence that cells may explode due to high mechanical stress and the Li Lab (Hokkaido University / Stockholm University) provided the statistical analysis of cell shape within a wide range of plant species.

Forced expression of this SMN1 variant in cultured non-neuronal cells induces the formation of neurite - like extensions, a change in cell shape reminiscent of that occurring when motor neurons send out axons to their muscle targets.

Methods: The team profiled lipids using analytical chemistry techniques and monitored changes in cell shape using capabilities in the Quiet Wing at EMSL, a Department of Energy national scientific user facility located at PNNL.

Thomas Widmann (Dahmann, MPG)-- «The role of Dpp and Wingless signaling gradients in directing cell shape during Drosophila wing imaginal disc development» (2009)

We have recently shown that signaling by BMP, once thought to maintain cell survival, helps to control epithelial cell shape and organization in the developing Drosophila wing.

During interphase they influence cell shape, motility, polarity and intracellular transport.

Katsanis notes that once inside a cell, the Wnt pathway splits into two branches that need to be balanced depending on the needs of each cell: the so - called canonical branch, which typically drives cells to multiply, and the non-canonical branch, which controls messages to refine cell shape and growth.

Feeding mice Roundup Ready soybeans exhibited changes in liver cell shape and structure that resembled the effect of a toxin; removing the GM soybeans from the diet reversed the effect.

Due to its structure HA also facilitates cell shape changes and movement of cells due to its role in the pericellular envelope which surrounds cells.

But the diptych is dominated by a large, organic, sprawling cell shape on the left, its inflated, microscopic form seemingly about to engulf the aforementioned table and its occupants, in a classic surrealist reversal of real - world perspectives.

As cells jammed or unjammed, cell shapes changed in a systematic manner in both systems, thus suggesting a common physical basis.