Not exact matches
During intense or extensive exertion, the sickle hemoglobin can change the
shape of red blood
cells from round to quarter - moon, or «sickle.»
The scientists» findings have wide implications in the effort to understand how organs are sculpted into their
shapes and how
cells respond to their native mechanical environment both in healthy tissues and
during disease.
During her postdoctoral work, Bissell noticed that removing mammary
cells from a mouse and putting them into a culture dish caused them to lose not only their normal in vivo
shapes, but also their ability to secrete milk.
Apart from advancing our understanding of how plants regulate their growth and
shape, this research presents new questions for stem
cell researchers in regards to
cell size checkpoints and their importance
during organism development.
Lin observed that this change in nucleus
shape is similar to what occurs
during cell division and hypothesized that there may be similar underlying mechanisms behind
cell division and regeneration.
The orientation - specific edge - apposing activity of these «border
cells» is maintained when the environment is stretched and
during testing in enclosures of different size and
shape in different rooms.
This relationship is perhaps most striking
during the first stages of embryogenesis, when
cells change in size and
shape several fold in the absence of growth.
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Our insight will substantially enhance our understanding of dynamic
cell shape regulation for instance in the context of
cell migration as in cancer metastasis or
during morphogenesis.
«The plasma membrane also dynamically changes
shape during cell migration, cancer
cell invasion,
cell division, nutrient uptake, and entry of pathogens and viruses into
cells,» Shin explains.
During interphase they influence
cell shape, motility, polarity and intracellular transport.
In the light of a review detailing the role of these genes in the
cell shape changes leading to invagination, and of recent findings showing the expression of twist as mechanically sensitive, we suggest that the expression of twist in the mesoderm could alternatively be maintained by mechanical strains developed
during mesoderm invagination.
«
Shape changes occur
during cell division, when a mother
cell divides into two daughter
cells during embryo development.
During the culture of these
cells, we noticed a change in
cell morphology from the cobble stone - like
shape typical of epithelial
cells to a more spindle - like and scattered appearance (Figure 2A, lower panel), indicating these
cells may be undergoing EMT.
Within the Maze,
during 1975, several H -
shaped buildings, called H - blocks were constructed, each with four small wings of 25
cells.