Sentences with phrase «cell shape led»

Dr Sánchez - Corrales» search for an adequate mathematical representation for cell shape led the group to discover there were inherent errors in quantifying shape properties through a traditional method named the Elliptic Fourier Analysis, named after Joseph Fourier the French mathematician and physicist.

Not exact matches

This unnatural and forced movement of water changes vaginal cell shape and biology for the worse and can lead to tissue damage, irritation, and general disruptions to the vaginal ecosystem.

Hochstein is lead author of a study that explains how a lemon - shaped virus assembles itself and how the virus ejects the DNA it carries into host cells.

The disease is caused by the accumulation of abnormally shaped α - synuclein proteins in neurons, leading to particularly toxic effects in dopamine - releasing cells located in brain regions that control movement.

In the disease state, the blood cells are sickle - shaped instead of round, leading to stabs of pain and eventual organ damage.

In sickle cell anemia, a single genetic mutation leads to abnormal, crescent - shaped red blood cells that clot in tiny blood vessels throughout the body, causing severe pain and eventual organ damage.

Top series: Images show the elongated shape of cells transforming into a ball shape before they shed from the lining of the airway to cause obstruction, a key reason why RSV leads to bronchiolitis.

This change can lead to severe anemia and abnormally shaped red blood cells that can block the flow of blood, causing organ damage.

In a paper published Sept. 21 in Cell, Harvard Medical School genetics professor Olivier Pourquié — whose lab discovered the segmentation clock 20 years ago — and colleagues report that they used mouse cells to reconstitute a stable version of this clockwork for the first time in a petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes shape.

Published in Nature Neuroscience, the findings suggest that astrocytes — star - shaped cells that are abundant in the brain and support neuronal function — are important regulators of information storage, and their dysfunction might lead to memory decline in disease.

Aging in intestinal stem cells leads to changes in villi, the finger - shaped protuberances that line the small intestine and absorb nutrients, and crypts, the valleys between villi where the intestinal stem cells live.

With the honeycomb shape, this eventually led to an oval ring of cells within the pore — with the majority aligned along the long axis.

Her hope is that this fundamental understanding of Stentor's regeneration process will help clarify the connections between regeneration and cell division, leading to new, broader insights about how cells produce and maintain their shape.

«I'm interested in understanding how single cells maintain their proper shape,» said Athena Lin, graduate student at the University of California, San Francisco, and lead researcher on the project.

«The cells began to take on the shape of liver cells, and even started to perform regular liver - cell functions,» said UCSF Postdoctoral Scholar Milad Rezvani, MD, the paper's other lead author.

In a study published in Molecular Cell this month, Alexei V. Tulin, PhD, Associate Professor at Fox Chase Cancer Center, and colleagues reported that chemical modification of one type of histone — called H2Av — leads to substantial changes in nucleosome shape.

They have a disruptive mutation in the gene for the blood cell molecule hemoglobin; as a result, their red blood cells typically take on a sickle shape, which causes them to clog up blood vessels, leading to intense pain, especially in the long limb bones.

Genetic «signatures» of early - stage embryos confirm that our development begins to take shape as early as the second day after conception, when we are a mere four cells in size, according to new research led by the University of Cambridge and EMBL - EBI.

According to Quan Zhu, Ph.D., the co - lead author of the paper, this structure is situated in the middle of the «X» like shape created when a chromosome duplicates itself just before cell division.

Our combined in vitro and in vivo expertise shapes a broad portfolio of design (ES cell, CRISPR / Cas9, random DNA insertion), breeding and associated services to create and maintain the most relevant models for your studies.Rely our industry - leading germ line transmission, strict quality controls, fast turnaround and dedicated project managers to help you successfully reach your goals.

In the light of a review detailing the role of these genes in the cell shape changes leading to invagination, and of recent findings showing the expression of twist as mechanically sensitive, we suggest that the expression of twist in the mesoderm could alternatively be maintained by mechanical strains developed during mesoderm invagination.

Sickle cell disease (SCD) is caused by a genetic abnormalities in the hemoglobin genes which leads to the production of abnormally shaped mature red blood cells, provoking various acute and chronic complications with an accompanying high mortality rate [1].

For those suffering from lead or other heavy metal poisoning, a protective diet that avoids processed foods and emphasizes the central components of a nutrient - dense and antioxidant - rich WAPF - style diet is essential (see sidebar).21 Nutritional status shapes susceptibility to lead toxicity in important ways, affecting lead's intestinal absorption; its mobilization, distribution and retention in the body; and excretion.22 Because oxidative stress is a likely mechanism explaining some of lead's toxic actions, some investigators have begun to explore whether natural antioxidants and trace minerals may help mitigate lead - induced cell damage.17 Specifically, researchers in Spain found that administration of vitamins A, B6, C and E along with zinc modulated some of the negative effects of lead exposure in rat pups, confirming the influence of nutritional factors on health outcomes following lead exposure.17 Vitamin D also should be a major component of a protective diet.

Year 6 Science Assessments and Tracking Objectives covered: Describe how living things are classified into broad groups according to common observable characteristics and based on similarities and differences, including micro-organisms, plants and animals Give reasons for classifying plants and animals based on specific characteristics Identify and name the main parts of the human circulatory system, and describe the functions of the heart, blood vessels and blood Recognise the impact of diet, exercise, drugs and lifestyle on the way their bodies function Describe the ways in which nutrients and water are transported within animals, including humans Recognise that living things have changed over time and that fossils provide information about living things that inhabited the Earth millions of years ago Recognise that living things produce offspring of the same kind, but normally offspring vary and are not identical to their parents Identify how animals and plants are adapted to suit their environment in different ways and that adaptation may lead to evolution Recognise that light appears to travel in straight lines Use the idea that light travels in straight lines to explain that objects are seen because they give out or reflect light into the eye Explain that we see things because light travels from light sources to our eyes or from light sources to objects and then to our eyes Use the idea that light travels in straight lines to explain why shadows have the same shape as the objects that cast them Associate the brightness of a lamp or the volume of a buzzer with the number and voltage of cells used in the circuit Compare and give reasons for variations in how components function, including the brightness of bulbs, the loudness of buzzers and the on / off position of switches Use recognised symbols when representing a simple circuit in a diagram

Active front grille, with grille louvers that open when the fuel cell stack requires cooling Full underbody aerodynamic cover Left - and right - hand charging ports incorporated in stylish front fender vents Flush door handles that feature push - to - release operation Wind tunnel - shaped outside mirrors with integral turn signals Center high - mounted rear stop lamp incorporated into full - width, wraparound spoiler Signature vertical taillamps with subtle fin design Side glass mounted flush with pillars Wheels with clear - covered space between the spokes, creating a sleeker profile while maintaining Cadillac's signature bold wheel design Low - drag roof rack «From the strong, shield grille and vertical headlamps to the crisp body lines, the Provoq is instantly recognizable as a contemporary Cadillac,» said Hoon Kim, exterior lead designer.

The Provoq has a sleek, athletic shape that builds on the second generation of Cadillac's design renaissance, led by the 2008 CTS, with dynamic and purposeful features that support the hydrogen fuel cell powertrain and contribute to the vehicle's overall efficiency.