«This model supported cancer development so strongly that some mice developed invasive squamous
cell skin cancers similar to the patient's tumor,» said lead author Shadmehr Demehri, MD, PhD, a dermatologist and postdoctoral fellow.
Not exact matches
The treatment is promising enough that research teams around the world are developing
similar stem
cell therapies that can target and eradicate
cancers of the prostate, lung, breast,
skin and other tissues.
We have developed a sequencing based approach to show
similar in human tissues, finding around a third of
cells in normal sun exposed facial
skin carry
cancer driver gene mutations.
Differentiation of bCSCs led to an increase in DNA methylation suggesting that the hypomethylated state is characteristic of immature
cancer cells,
similar to that that observed for normal blood and
skin stem
cells [3].
Similar to the mouse study above, another group looked at
skin tumors (squamous
cell carcinoma) in a group of mice prone to such
cancers, to see if acute stress could modify this.