Sentences with phrase «cell state defined»

Not exact matches

Now — estoeric concepts such as «the soul» put aside for a moment (since The Bible states that nobody can know when ensoulment happens despite the many differing opinions from prominent theologians throughout the ages), what characteristics define a human being and how does a single cell possess them all?

Trauner explains the advantages of the method as follows: «The properties of light can be very precisely manipulated, so that we can modulate the state of the cells in a defined fashion.

«We've been trying to understand both how the different states a cell finds itself in can be defined by the markings on the histones surrounding its DNA, and to find an objective way to define the «age» of a cell,» said Rando, who is also director of Stanford's Glenn Laboratories for the Biology of Aging and deputy director of the Stanford Center on Longevity.

Over the years, Dr. Nimer has conducted extensive clinical and basic science research into the treatment and genetic basis of adult leukemia and bone marrow failure states, defining the regulatory mechanisms that control the production of blood cells and exploring ways to improve the treatment of blood based cancers.

Defined basic principles of how skeletal and cardiac muscle cells adapt to changing physiological demands associated with exercise or disease states.

Researchers at the Université libre de Bruxelles, ULB define for the first time the tumor transition states occurring during cancer progression and identify the tumor cell populations responsible for metastasis.

At any given instant it can be argued that the cell is in a «state» defined by its components — their concentrations and locations, the interactions between components — that are modulated in space and time, and the complex circuitry — that involves a large number of interacting networks and a snapshot of the dynamical processes — such as gene expression, cell cycle, transport of components, etc..

Several recent studies have shown that cells can be returned to pluripotent state using «defined factors» (specific proteins that control which genes are active in a cell), a technique pioneered by Dr. Shinya Yamanaka, a professor at Kyoto University in Japan.

In light of the observation that iPS cell derivation takes place under the same culture conditions used for ES cells [20], we hypothesized that these human feeder cells could offer a stable tool for defining molecular hallmarks during conversion of differentiated somatic cells to the pluripotent state.

The model in Figure 9 represents a stable dynamic system in which the transcriptional state of individual cells shifts, but only within the boundaries defined in red.

Their method also provides a means to assess the relative merits of RNA and protein measurements in defining the states of cells.

In primary cells, we quantified multiple transcripts, with the identity and functional state of each analyzed cell defined on the basis of the expression of a separate set of transcripts or proteins.

Ninety functional regions of interest (ROIs) were defined across 14 large - scale resting - state brain networks to generate a 3960 cell matrix reflecting whole - brain connectivity.

This type of regulation poises the cell between adaptability and stability, likely to be a defining state for pluripotent stem cells.

These stem cells are called induced pluripotent stem cells (iPSCs) IPSCs are adult cells that have been genetically reprogrammed to an embryonic stem cell — like state by being forced to express genes and factors important for maintaining the defining properties of embryonic stem cells.

By developing a simple chemically defined culture system permitting efficient differentiation of numerous human iPS cell lines toward cells of a mature hepatic state, we now demonstrate the possibility of modeling groups of diseases of non-neuronal origin whose phenotypes are a consequence of complex protein dysregulation within adult cells.