Sentences with phrase «cell state from»

Johns Hopkins scientists have developed a reliable method to restore blood cells into a primitive stem cell state from which...

Not exact matches

In a decision released by the Baltimore Circuit Court, Judge Martin P. Welch wrote that the 35 - year - old was being granted a new trial because his initial council failed to properly cross-examine an expert from the state about the reliability of cell tower data that seemed to place him at the scene of the crime.

Despite its poverty and isolation, North Korea has poured resources into a sophisticated cyber-warfare cell called Bureau 121, defectors from the secretive state said as Pyongyang came under the microscope for a crippling hack into computers at Sony Pictures Entertainment.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

«Since the ADD / CVD only impacted Chinese and Taiwanese cells, they could source cells from other markets (e.g. South Korea), do the assembly in the United States, and bypass the ADD / CVD,» Zoco tells pv magazine.

CNN: Sandusky's pastor addresses conviction from pulpit Jerry Sandusky sits in a county jail cell in Bellefonte, Pennsylvania, but his presence and the weight of the 45 guilty verdicts rendered against the former Penn State football coach on Friday night hung in the air Sunday morning at the State College church where he and his wife are longtime members.

A new flight restriction out of the Trump administration will keep passengers on United States - bound flights from eight Muslim - majority countries from carrying on any electronics bigger than a cell phone.

The ultimate goal of our laboratory is to generate ES - like cells directly from somatic cells by nuclear reprogramming... which converts adult cells back into embryonic state.

Now — estoeric concepts such as «the soul» put aside for a moment (since The Bible states that nobody can know when ensoulment happens despite the many differing opinions from prominent theologians throughout the ages), what characteristics define a human being and how does a single cell possess them all?

A pluripotent state makes the resulting cells indistinguishable from embryonic stem cells, and the scientists got these cells without creating or destroying any embryos.

Though there have been many strides made towards ending the HIV / AIDS epidemic, such as the recent breakthrough of scientists using gene editing to remove HIV from the genome of T - cells, there is still much work to be done with over 1.2 million in the United States living with the disease.

I watched this game, with unfettered excitement and inebriation, from The Rathskellar in State College, Pennsylvania, and proceeded to spike my cell phone into a million pieces in the middle of the bar.

A friend of mine (she now has two PhDs, both from excellent institutions) implied that I was a racist and colonial imperialist because I stated that your eye colour is dependent on the DNA in your cell nuclei WHETHER YOU»VE EVER HEARD OF DNA OR NOT (ie, DNA exists whether you believe in it or not).

Dr. Devra Davis PhD., MPH, founder of Environmental Health Trust (EHT) and an award - winning, internationally renowned scientist who also was the founding director of the Board on Environmental Studies and Toxicology of the U.S. National Research Council, National Academy of Sciences, states: «No studies show that microwave radiation exposure in children is safe or that continuous exposure from cell phones, cell towers, cordless phones, Wi - Fi routers, baby monitors, etc. is safe.»

Sampling was conducted via a stratified dual frame probability sample of landline and cell phone telephone numbers (both from Survey Sampling International) from within New York State weighted to reflect known population patterns.

Sampling was conducted via a stratified dual frame probability sample provided by Survey Sampling International of landline and cell phone telephone numbers from within New York State weighted to reflect known population patterns.

The revenue is generated through a public safety surcharge on cell phone bills, however Erie County hasn't received its fair share from the state.

And drones are not the only evidence of our expanding, and dangerous, surveillance state ***************** Congressional investigators have gotten, for the first, some data on how many law enforcement requests are made to the 9 major cell phone carriers for information on citizens.Hang on to your hats and bonnets, and sit down!It appears that there were at least 1.3 million cell - phone demands from law enforcement last year... and all without a court order.

Cell phones, smart phones, and other personal electronic devices are free from arbitrary police snooping in California — at least for the time being, thanks to actions taken by the state legislature and Governor Jerry Brown.

A state - level committee she created in 2014 with funds from two city - level accounts has been more active, reporting payments for consulting services, storage and cell phone bills.

Scarborough, who served in the legislature for more than 20 years, told reporters that officials from the FBI and the office of New York State Attorney General Eric Schneiderman seized his cell phone, calendars and «just about everything,» another report said.

Jonathan said arrests have been made which led to the wiping out of a cell of the group from Niger State.

The researchers from Columbia University and New York State Psychiatric Institute found that even the oldest brains they studied produced new brain cells.

The grand plan envisioned by Ohio State University investigator Nicanor Moldovan and his colleagues entails sowing cells harvested from vessel lining, or endothelium, in silicon molds shaped like capillaries.

«Fat cells can adopt a range of metabolic phenotypes, depending on physiological conditions and location in the body,» said James G. Granneman, Ph.D., a researcher involved in the work from the Center for Integrative Metabolic and Endocrine Research at the Wayne State University School of Medicine in Detroit, MI.

The most promising chemical — sulforaphane, a naturally occurring compound found in cruciferous vegetables — tamped down glucose production by liver cells growing in culture, and shifted liver gene expression away from a diseased state in diabetic rats.

The findings, from the Emory / Johns Hopkins / Florida State team that showed this spring that neural progenitor cells are particularly vulnerable to Zika infection, were published in Nucleic Acid Research.

Then his team turned to liver cells, which seemed from previous reprogramming experiments to be easier to send back to an embryonic state.

Meanwhile, cell biologist Paul Durham and his team from Missouri State University are working on a multitasking bandage layered with antifungal, antibacterial, and anti-inflammatory agents for use on a variety of wounds, including deep cuts and punctures.

With the tumor in this vulnerable state, the researchers strike again by shutting down the cell's ability to mitigate the toxic stew it creates from its own deranged metabolism.

Analyzing tissue specimens from 10 people with stomach cancer, the researchers found evidence that those same mature cells in the stomach also had reverted to a stem cell - like state and had begun to change and divide rapidly.

When the laser is switched off, the water returns to its high - density state, forcing the cell to «suck in» water and any other molecules, including drugs, from its surroundings.

«By learning how tau spreads, we may be able to stop it from jumping from neuron to neuron,» said Karen Duff, PhD, professor in the department of pathology and cell biology (in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain) and professor of psychiatry (at New York State Psychiatric Institute.)

Scientists in the United States have been trying to find ways around the ban on using federal funds to create stem cells from human embryos.

And what happens in the fresh state is basically when respiration ends, when we stop breathing and we stop clearing toxins from cells, all those processes that were ongoing — and the cells don't know what yet, right; the rest of the body, the heart has stopped, the brain is stopping, but the cells still have some chemistry that's going on after the body has died.

The stem cells, derived from human umbilical cord - blood and coaxed into an embryonic - like state, were grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.

With collaborators from India, Japan, and the United States, the inStem lab is exploring «biochemistry, biophysics, humanized mouse models, and single - cell models.»

In the United States, Mackenzie's group and another have embraced a different approach: treating fetuses with blood stem cells culled from their mothers, the strategy she began exploring in animals almost a decade ago.

Fact: The WI - 38 and MRC - 5 cell lines, derived from two fetuses that were aborted, respectively, in 1962 in Sweden and in 1966 in the United Kingdom, are used to produce the following vaccines, all licensed and marketed in the United States:

This year they succeeded in generating mini-livers, or liver buds, from stem cells that were taken from human skin and reprogrammed to an embryonic state.

Jeanne Lawrence at the University of Massachusetts Medical School in Worcester took skin cells from men with the condition and «rewound» them into an embryonic state.

«I routinely see where individual stem cell centers in the United States receive donations from some high - net - worth individuals in the range of $ 50 million — you don't see that happening routinely here in the UK,» says KCL's Minger, an American who moved to the UK about 13 years ago.

«We can work with any embryonic stem cell line from any source and are not restricted to working with the very small number of federally approved lines as is the case for researchers in the United States,» says Minger.

These are cells taken from adult non-muscle tissues, such as skin or blood, and reprogrammed to revert to a primordial state.

Then the researchers, led by then - post-doc, now Oregon State University faculty member Matthew Robinson and colleagues, took biopsies from the volunteers» thigh muscles and compared the molecular makeup of their muscle cells to samples from sedentary volunteers.

Previously, researchers have produced hydrogen gas in microbial - powered, batterylike fuel cells, but only when they supplemented the energy produced by the bacteria with electrical energy from external sources — such as that obtained from renewable sources or burning fossil fuels, says Bruce Logan, an environmental engineer at Pennsylvania State University, University Park.

Pfizer's Selzentry (generic name, maraviroc), which went on sale in the United States in September, binds with host cell receptors to prevent the virus from attaching to and entering healthy host cells.

The study was supported by a Science of Human Appearance Career Development Award from the Dermatology Foundation and by grants from the Medical Research Council of the UK, the Empire State Development's Division of Science, Technology and Innovation (NYSTAR), New York Stem Cell Science (NYSTEM), and the Biotechnology and Biological Sciences Research Council in the UK (BBSRC), as well as earlier support from the Steven and Michele Kirsch Foundation.

However, only rigorous science and responsible regulation can ensure the safe and effective translation of science into effective therapies,» remarked Paolo Bianco, Pathologist, Stem Cell Biologist, Professor of Pathology at the University of Roma «La Sapienza» and one of the 13 authors of the commentary who come from Italy, Germany, the United Kingdom, The Netherlands and the United States.

The disease model, described in a new study by a UC San Francisco - led team, involves taking skin cells from patients with the bone disease, reprogramming them in a lab dish to their embryonic state, and deriving stem cells from them.