Until now, scientific dogma has stated that differentiation is a one - way path; once cells specialize, they can not return to the flexible stem -
cell state on their own.
Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required
on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for
state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and
state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize
cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact
on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
This statement is in sharp contrast to the statements of analysts at IHS Markit and GTM Research that new
cell and module factories in the United
States do not make economic sense despite the imposition of tariffs
on imported modules.
Earlier in his career, Scott served as the founding Executive Vice President at Solar
Cells, Inc. (now First Solar), the President of Glasstech Solar, Inc. (a manufacturer of semiconductor equipment for the solar industry), and consultant to venture capital firms and
state agencies
on renewable technologies and markets.
This week
on Ride the Lightning: Tesla Motors Unofficial Podcast: «Tesla has officially begun battery
cell production at the Gigafactory, one
state...
I was very niave as alot of commenters are here today
stating that abortions only take place
on a blob of
cells.
CNN: Sandusky's pastor addresses conviction from pulpit Jerry Sandusky sits in a county jail
cell in Bellefonte, Pennsylvania, but his presence and the weight of the 45 guilty verdicts rendered against the former Penn
State football coach
on Friday night hung in the air Sunday morning at the
State College church where he and his wife are longtime members.
Whether I use the expression «momentary self» or the word «monad,» what I am in fact doing is setting a limit,
on no validly argued grounds, to the dissolution of the «total temporary
states» into a purely ad hoc combination of inexplicable and inexplicably organized collections of bodily
cells, sensations, intentions, thoughts, nervous processes, desires, and the like.
A new flight restriction out of the Trump administration will keep passengers
on United
States - bound flights from eight Muslim - majority countries from carrying
on any electronics bigger than a
cell phone.
«Garcia - Falgueras and Swaab
state in the abstract of their 2010 study, «The fetal brain develops during the intrauterine period in the male direction through a direct action of testosterone
on the developing nerve
cells, or in the female direction through the absence of this hormone surge.
In this proposal, specific master genes that are required for the pluripotent stem -
cell state would be turned
on in an adult
cell.
«Garcia - Falgueras and Swaab
state in the abstract of their 2010 study, «The fe - tal brain develops during the intraut - erine period in the male direction through a direct action of tes - tosterone
on the developing nerve
cells, or in the female direction through the absence of this hor - mone surge.
State College, Pennsylvania (CNN)-- Jerry Sandusky sits in a county jail
cell in Bellefonte, Pennsylvania, but his presence and the weight of the 45 guilty verdicts rendered against the former Penn
State football coach
on Friday night hung in the air Sunday morning at the
State College church where he and his wife are longtime members.
I was sitting at a meeting and a colleague got a call
on the
cell - phone and mentioned the
State building was
on fire...
Take my teen's
cell phone: He received it in 6th grade, which may be early or late depending
on your beliefs / community / needs, but he was going out of
state with a friend's family and I wanted him to be able to contact me (and me him) at any time.
A friend of mine (she now has two PhDs, both from excellent institutions) implied that I was a racist and colonial imperialist because I
stated that your eye colour is dependent
on the DNA in your
cell nuclei WHETHER YOU»VE EVER HEARD OF DNA OR NOT (ie, DNA exists whether you believe in it or not).
Dr. Devra Davis PhD., MPH, founder of Environmental Health Trust (EHT) and an award - winning, internationally renowned scientist who also was the founding director of the Board
on Environmental Studies and Toxicology of the U.S. National Research Council, National Academy of Sciences,
states: «No studies show that microwave radiation exposure in children is safe or that continuous exposure from
cell phones,
cell towers, cordless phones, Wi - Fi routers, baby monitors, etc. is safe.»
In the article, Dr. Margot Sunderland, author of the best - selling book What Every Parent Needs To Know,
stated that leaving a child in a
state of distress for a prolonged period without offering comfort affects them
on a cellular level, specifically the «migration» of their
cells as they get to where they need to be.
In the case of ISIS and Twitter, imagine a retaliatory attack
on a hacker
cell that ends up killing civilians in large numbers by accident, creating international pressure against the U.S. bombing campaign against the Islamic
State.
The reporter, Daily News Capitol Bureau Chief Ken Lovett, who has been covering
state government for decades, was arrested by the State Police for talking on his cell phone in the lobby of the Capitol outside the state Senate, in violation of a Senate
state government for decades, was arrested by the
State Police for talking on his cell phone in the lobby of the Capitol outside the state Senate, in violation of a Senate
State Police for talking
on his
cell phone in the lobby of the Capitol outside the
state Senate, in violation of a Senate
state Senate, in violation of a Senate rule.
Off topic questions included his speech tomorrow to Britain's Labour Party, Chirlane McCray's attendance at an NYPD CompStat meeting, whether ISIS and the recent U.S. military strikes will cause a ramped - up security / counter-terrorism effort by the City, Governor Cuomo's efforts at supporting a Democratic
state senate, Congressional approval of military strikes ordered by President Obama, the City school system's policy
on student
cell phones and continuing problems at Rikers Island.
The
state senator's phone records show that he called Bonomo's
cell phone at 10:42 a.m
on Jan. 10, 2013.
«I think I'm the only elected official in New York
State that's openly HIV positive,» Johnson said, «and my
cell phone
on a daily basis reminds me when I have to take my medicine and when I have to go to the doctor.»
Little said the Senate's plan also contains tax relief for North Country families and businesses, and rejects a number of «tax - and - fee increases» proposed by the governor, including new Department of Motor Vehicles fees, a surcharge
on pre-paid
cell phones and a proposal calling for online marketplaces to collect sales tax
on behalf of their vendors, a loophole that governor says is costing
state and local authorities $ 275 million in uncollected tax every year.
The revenue is generated through a public safety surcharge
on cell phone bills, however Erie County hasn't received its fair share from the
state.
And drones are not the only evidence of our expanding, and dangerous, surveillance
state ***************** Congressional investigators have gotten, for the first, some data
on how many law enforcement requests are made to the 9 major
cell phone carriers for information
on citizens.Hang
on to your hats and bonnets, and sit down!It appears that there were at least 1.3 million
cell - phone demands from law enforcement last year... and all without a court order.
Sen. Brad Hoylman has asked the
state Committee
on Open Government whether a Senate rule banning the use of
cell phones to take pictures violates the
state's open meetings law.
The right to organize, though apparently enshrined in the
state constitution, does not apply to farmworkers Espada showed up at the farm
on Friday and
cell phoned the owner to berate him for the conditions
on the farm and to tell him that the
state was going to pass a law making his life more difficult.
We Democrats are
on track this year to take all
State - wide offices and to come closer to our goal of taking over the
State Senate, so that our legislation, including D.R.I.E. parity with seniors, Timothy's Law, inclusion of PWDs in the EPIC senior prescription program, and funding for stem
cell research, can be passed.
Cuomo noted the
state spends $ 40,000
on a jail
cell and that reentry and alternative programs are always less expensive.
Radar, flashy LED signs, and text alerts to drivers»
cell phones and local police are part of New York's new, high - tech effort to combat often fatal wrong - way crashes
on the
state Thruway.
Last night, my
State Governor, Dr. Abdulfatai Ahmed revealed to me an information at his disposal that a group of suspects who had been in police
cells for several weeks for cultism and whose investigation had been concluded with prosecution about to commence under the
State law based
on the advice of the Director of Public Prosecution (DPP) and the Ministry of Justice were ordered to be transferred to Abuja this morning.
Low - wage workers would have more money in their pockets if the
state rolled back fees
on cell phones and gasoline rather than raising the minimum wage, he says.
One of the latest twist of the story told
on Wednesday was by Senate President Saraki who announced that his
State governor and ally, Abdulfatai Ahmed had told him that a group of suspects who had been in police
cells for several weeks for cultism and whose investigation had been concluded with prosecution about to commence under the
State law based
on the advice of the director of public prosecution (DPP) and the Ministry of Justice, were ordered to be transferred to Abuja
on the directive of IGP) Idris Ibrahim.
Mr. Adams serves
on the Empire
State Stem
Cell Board, the Board of Directors of the Brooklyn Community Foundation and the Steering Committee of the Association for a Better New York.
Gov. Andrew Cuomo announced today that New York
State will soon be on Ebay — well not the entire state — just hundreds of state vehicles, cell phones, medical equipment, highway equipment, officer furniture, cameras and genera
State will soon be
on Ebay — well not the entire
state — just hundreds of state vehicles, cell phones, medical equipment, highway equipment, officer furniture, cameras and genera
state — just hundreds of
state vehicles, cell phones, medical equipment, highway equipment, officer furniture, cameras and genera
state vehicles,
cell phones, medical equipment, highway equipment, officer furniture, cameras and generators.
On Thursday, the United Nations» member
states will consider two resolutions: One resolution would ban all human cloning methods, including efforts to use cloned embryonic stem
cells to try and generate healthy tissues, or to treat degenerative diseases such as Parkinson's.
In this
state, the
cells may not be able to reproduce or grow, but they would still be able to run repairs
on cell machinery.
«Fat
cells can adopt a range of metabolic phenotypes, depending
on physiological conditions and location in the body,» said James G. Granneman, Ph.D., a researcher involved in the work from the Center for Integrative Metabolic and Endocrine Research at the Wayne
State University School of Medicine in Detroit, MI.
Although the U.S. government puts stringent restrictions
on funding for research
on embryonic stem
cells, individual
states such as California have set up institutes to perform that work and general stem
cell studies.
Meanwhile,
cell biologist Paul Durham and his team from Missouri
State University are working
on a multitasking bandage layered with antifungal, antibacterial, and anti-inflammatory agents for use
on a variety of wounds, including deep cuts and punctures.
With respect to the latter, it
states, «no one shall be under a duty to participate in any manner of research
on human stem
cells to which he has a conscientious objection.»
Only movie stars and select consumers have been able to get their hands
on hydrogen fuel
cell vehicles in the United
States over the past few years, but now these zero - emissions cars are poised to bust onto the scene in a big way around 2015 to 2017.
Interestingly, two additional Nature papers released simultaneously with the Regev and Kuchroo team's study revealed that ILC2
cells in the gut also express Nmur1, take
on an inflammatory
state when exposed to NMU, and live in close proximity to NMU - producing nerve
cells.
«By learning how tau spreads, we may be able to stop it from jumping from neuron to neuron,» said Karen Duff, PhD, professor in the department of pathology and
cell biology (in the Taub Institute for Research
on Alzheimer's Disease and the Aging Brain) and professor of psychiatry (at New York
State Psychiatric Institute.)
Scientists in the United
States have been trying to find ways around the ban
on using federal funds to create stem
cells from human embryos.
And what happens in the fresh
state is basically when respiration ends, when we stop breathing and we stop clearing toxins from
cells, all those processes that were ongoing — and the
cells don't know what yet, right; the rest of the body, the heart has stopped, the brain is stopping, but the
cells still have some chemistry that's going
on after the body has died.
The «kind of murky status quo» that exists now for regulating stem
cell clinics «is quite different than there being laws
on the books that explicitly say that what the clinics are doing is legal at the
state level,» Knoepfler wrote in an email.
The postdoc, who did not want to be identified for fear of drawing unwanted attention, must now decide whether to continue with his work
on stem
cells — gambling that the U.S. government by summer will be inclined to grant him an extension — or spend the next half - year boning up
on techniques that will help him secure a position outside the United
States.
According to researchers, such margin guidelines are needed because as many as two - thirds of the hundreds of thousands of suspicious skin moles removed each year in the United
States require re-excision (further cutting out of mole
cells missed
on the first attempt).