Sentences with phrase «cell studies by»

By pushing the boundaries of bioinformatics, a collaboration led by Mei - Chong Wendy Lee and Nader Pourmand at the University of California, Santa Cruz charted more than 80,000 pieces of RNA per new cancer cell — typically, single - cell studies by other approaches look at hundreds or so RNA pieces to distinguish fairly different cells from one another.

One preliminary cell study by researchers at Sejong University in South Korea found that piperine may impact fat cells.

Not exact matches

A great study done in 2010 indicated that drinking fat - free milk immediately after whole - body resistance training and again one hour after the workout allowed participants to increase fat loss, gain greater muscle and strength, and strengthen bones by reducing bone cell turnover.

«In everyday interactions with significant others, people often assume that momentary distractions by their cell phones are not a big deal,» another researcher involved in the study, Meredith David, said.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Chicago, GenomeWeb — A new study by researchers from Memorial Sloan Kettering Cancer Center has demonstrated the predictive power of an AR - V7 protein expression test using Epic Sciences» non-EPCAM-based circulating tumor cell detection platform, which could help guide treatment decisions for men with metastatic castration - resistant prostate cancer.

February 2, 2017 By Ann Perry http://mbd.utoronto.ca/ When Arif Aziz learned last fall about a new independent study project that was bringing together MBA candidates and PhD students in health sciences and engineering to map the global market for stem cell therapies, he jumped at the opportunity.

Lie4Him, Schweitzer, one of the first scientists to use the tools of modern cell biology to study dinosaurs, has upended the conventional wisdom by showing that some rock - hard fossils tens of millions of years old may have remnants of soft tissues hidden away in their interiors.

A team led by David Sinclair of the University of New South Wales published a study in Cell, saying that they have actually reversed mice's aging process.

These were not studies published in fly - by - night oncology journals, but blockbuster research featured in Science, Nature, Cell, and the like.

Studying the Bible in his cell, he was struggling to understand what the apostle Paul meant in his letter to the Romans: «For in the gospel the righteousness of God is revealed — a righteousness that is by faith from first to last, just as it is written: «The righteous will live by faith»» (1:17).

One can not explain the tree by a study of the cells apart from the tree.

The objects of his study range from a class of molecules that have the basic self - duplicating property of living things, through cells which suggest purely physical systems, through animals which give increasing evidence of having minds, to human beings in whom streams of consciousness seem to involve continual choices of action, at the opposite pole from control by impersonal laws of nature.

In a lab study, an extract of the leaves stopped the growth and progression of prostate cancer cells by up to 75 % in mice.

Other studies show that the goji berry benefits eye health by protecting the retina from ganglion cells so goji antioxidants act as a natural treatment for glaucoma.

Although much less research exists on monk fruit and its components, preliminary studies show promise for improving insulin signaling by protecting the pancreatic insulin - releasing cells from oxidative stress (3, 4).

A Canadian study published this year around the same time titled «Coconut oil protects cortical neurons from amyloid beta toxicity by enhancing signaling of cell survival pathways» observed that coconut oil and its medium chain fatty acids (MCFAs) protect against amyloid beta (Aβ) induced neurotoxicity in primary rat cortical neurons.

Studies have shown that these cancer - fighting compounds and enzymes found in broccoli and other cruciferous vegetables may actually prevent the relapse of certain cancers by killing cancer stem cells.

It is perhaps for the best that these exiles tend to be short - lived: a recent study into the long - term effects of banter deprivation on professional footballers, sponsored by the PFA, had to be brought to a premature end after the players escaped from their holding cells.

According to a study published in April 2010 by the Pew Research Center, 75 percent of children ages 12 to 17 now have a cell phone.2 That said, it can be a struggle for parents to balance the family budget in order to keep the whole family in touch while on the go.

Recent studies have indicated that infant colic, gastroesophageal reflux, and constipation can all be caused or aggravated by cow's milk allergy — or intolerance, as it is called since it is cell - mediated and has a slower onset than reactions which involve IGE antibodies.

A 2013 study by Cheryl Watson at The University of Texas Medical Branch at Galveston found that even picomolar concentrations (less than one part per trillion) of BPS can disrupt a cell's normal functioning, which could potentially lead to metabolic disorders such as diabetes and obesity, asthma, birth defects or even cancer.

Plus, one branch of this mechanical family tree can also help power a village, charging cell phones and letting students study after dark by the light of LED bulbs.

«By studying the ways different proteins like keratin dynamically change within a cell, we can better understand the progression of cancers and other diseases,» they say.

The new study suggests that MDR1 is responsible for protecting TH17 cells in the gut from bile acids — detergent - like molecules produced by the liver that break down fats.

The shared patterns of gene expression in the limbs and phallus are generated in part by a common set of noncoding DNA, also called «elements» or «enhancers,» which act to control gene expression in both of these structures, argues a study published October 1 in Developmental Cell.

«Our study results are the first to argue that we may be able to treat inflammatory bowel disease and protect against transplant rejection not only by blocking TNF alpha as is done currently, but also by stimulating ATG16L1 to prevent early death of cells lining the gut,» says study senior investigator Ken Cadwell, PhD, an associate professor at NYU School of Medicine and NYU Langone Health's Skirball Institute for Biomolecular Medicine.

Co-authored by David Catling, an atmospheric chemist at the University of Washington in Seattle, the study peers deep into our planet's history to devise a novel recipe for finding single - celled life on faraway worlds in the not - too - distant future.

McCallion's strategy to make sense of all this data looks at the active genes in cells affected by a disease, groups of genes that interact with one another, their vulnerability to mutation and information from past scientific studies to filter more than a thousand gene candidates for disease risk down to just a handful within any one implicated region.

The study, led by Dr Len Stephens and Dr Phill Hawkins and published today in the journal Molecular Cell, reveals why loss of the PTEN gene has such an impact on many people with prostate cancer, as well as in some breast cancers.

The process takes place by means of a mechanism — unveiled in this study — that inhibits the activity of the osteoblasts, the cells that produce the bone matrix so that bones can grow during childhood and youth, and remain in good condition in adulthood.

In the new study, led by graduate student Steven Briscoe, the team found that other populations of neurons in the bird DVR share molecular signatures with neocortical intratelencephalic cells, or IT neurons.

By plucking out delicate, live tissue during neurosurgery and then studying the resident cells, researchers have revealed a partial cast of neural characters that give rise to our thoughts, dreams and memories.

Immunophenotyping — a laboratory procedure used to study the proteins expressed by cells — is very commonly used in basic science research as well as in laboratory diagnostic testing.

In Robinson's lab, Sharon studied protein - protein interactions within proteasomes, large multiprotein complexes that clear cells of unwanted proteins by degrading them into small peptide fragments.

«There was this initial thought that [circulating tumor cells] are only present at late stage,» says Sollier - Christen, but she notes that in the past year, several studies using more sensitive techniques have found such cells much earlier in tumor development, even before the tumor becomes visible by conventional imaging techniques.

In the present study, the researchers have discovered a reason for reduced fertility in people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in general.

This pilot research builds on an earlier study by Milovancev and collaborators that examined the ability of MRIs and CT angiograms to detect cancerous lesions related to FISS, and another study that looked at three methods for assessing margins for canine mast cell tumors and soft tissue sarcomas.

Speeches came from a variety of speakers, including a science broadcaster and writer, a Pakistani - born Canadian Muslim who works in STEM, a Pakistani - born professor who studies cell biology and anatomy; and, an emergency room physician who helped start the process to phase out coal - fueled power plants by 2030 in Alberta.

By studying human cancer cells and animal models of cancer in the lab, our researchers have shown that loss of PTEN leads to high levels of PI (3,4) P2, which could result in hyperactivation of AKT.

What's new in the Czech study, explains pathologist Carol Meteyer of the U.S. Geological Survey's National Wildlife Health Center in Madison, Wisc., is the confirmation of tissue damage characteristic of clinical white - nose sydrome: skin being digested by the pathogen as the fungi's fibrous segments enter a bat's wing and begin replacing its cells.

She studied T cells, including the role of a checkpoint inhibitor, for her Ph.D. and postdoctoral projects and at a startup company that was acquired by Novartis.

The diagnosis of cancer and study of disease progression is often accomplished by examining a tumor sample containing many billions or even trillions of cells.

In the 1980s, Dubochet got around a problem by developing a quick - freezing process that allowed water in cells to solidify, exposing each feature so it could be studied and examined.

«By studying its genome, we found that Loki represents an intermediate form in - between the simple cells of microbes, and the complex cell types of eukaryotes,» says Thijs Ettema.

The study also found that in addition to its role in determining the sex of somatic cells, Sxl regulation by m6A is required to initiate germline stem cell differentiation for developing eggs.

Workers in Chinese factories exposed to high levels of formaldehyde had lower counts of white blood cells that fight germs and diseases, according to a 2010 study led by Zhang.

«Chronic inflammation of the intestine is thought to be caused by abnormal interactions between gut microbes, intestinal epithelial cells and the immune system, but so far it has been impossible to determine how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.

In a groundbreaking study that provides scientists with a critical new understanding of stem cell development and its role in disease, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first - of - its - kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the embcell development and its role in disease, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first - of - its - kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the embCell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first - of - its - kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the embryo.

In a study published in Cell Reports, researchers lead by Cédric Blanpain, MD / PhD, WELBIO investigator and Professor at the Université libre de Bruxelles, Belgium, identified a novel lineage - restricted stem cell in the mammary glCell Reports, researchers lead by Cédric Blanpain, MD / PhD, WELBIO investigator and Professor at the Université libre de Bruxelles, Belgium, identified a novel lineage - restricted stem cell in the mammary glcell in the mammary gland.