This result reflected earlier findings that ILC and T
cell subclasses produce similar sets of cytokines, but also revealed differences in how the two cell types control the activities of these key immune response genes.
Not exact matches
To make the vaccine, cancer
cells are harvested from a tumor after surgery and stripped of their proteins; then those proteins are cultured with dendritic
cells, a
subclass of white blood
cells, drawn from the patient's blood.
One study showed that ovarian tumors produce a signaling molecule that serves to attract regulatory T
cells, a
subclass of adaptive immune
cells responsible for quieting other T
cells.
Recent work has revealed that ILCs and T
cells mirror each other in their
subclasses, which are defined by the kinds of cytokines they produce.
The study also demonstrates that the density of a specific
subclass of chandelier
cell cartridges is higher exclusively in layer 2 in the disease.
To trace the paths of the pyramidal
cells and see if
subclasses of
cells could be distinguished based on their downstream targets.
In addition, they hope to take the spatial recognition experiments to the next level using a new microscopy technology that could show simultaneous activity in both
subclasses of pyramidal
cells in a freely moving mouse.
In keeping with this, recent studies showed that flavanols, a
subclass of flavonoids that is richly represented in natural cocoa beans, increase NO production by cultured human vascular endothelial
cells (16) and improve endothelium - dependent vasorelaxation (NO - dependent) in finger (2) and brachial (3) arteries of healthy humans.
Recently, researchers demonstrated that pyramidal
cells may exhibit heterogeneity within the subiculum; in other words,
subclasses of these
cells may relay different signals to different areas of the brain.
LJI scientists are now exploiting immunotherapy approaches to antagonize these malignancies by identifying
subclasses of immune
cells capable of fending off invaders.
Recently, we reported the discovery of a specific
subclass of macrophages involved in the recognition of senescent
cells.
IgG
subclass antibodies have a half - life of 21 days, and stick around on immune
cells for about two to three months.