Sentences with phrase «cell suicide»

"Cell suicide" refers to a process called apoptosis, where cells in our body self-destruct in a controlled way. This natural process helps maintain the balance and health of our organs by eliminating damaged or unhealthy cells. Full definition
The symptoms of many diseases are caused by unwanted cell death, and the pathogens could be triggering abnormal cell suicide.
The genetic instructions that cause cell suicide are carried by every cell in our bodies.
Instead, these deaths appear to occur by cell suicide.
Perhaps the mechanism that drives cell suicide will evolve a more sophisticated function.
The scientists discovered that dinaciclib, by interfering with UPR activation, caused multiple myeloma and myeloid leukemia cells to initiate a form of cell suicide known as apoptosis when exposed to agents that induced ER stress.
Studies have shown gamma - tocotrienol selectively targets cancer cells, triggering cellular senescence and promoting apoptosis — a type of programmed cell suicide.
MAPK regulates cell functions, including proliferation, gene expression, differentiation, cell division and a form of cell suicide known as apoptosis.
When exposed to Zika virus before birth, mouse fetuses with the protein commit cell suicide, while fetuses without it continued to develop.
When activated, iASPP is shuttled into the nucleus, binds to p53 and ultimately inhibits its ability to induce cell suicide.
Wallach and his colleagues have shown these death domains can bind to one another inside human cells, triggering cell suicide in the absence of TNF.
Adding RNase L to a cell triggers cell suicide, suggesting the enzyme may prevent viruses from spreading, and may help suppress tumors by preventing cells from multiplying out of control.
Molecular analysis of the induced tumors revealed that the PMN - MDSCs in the induced tumors express high levels of a surface protein known as FAS - ligand, which induces T cell suicide when it binds its receptor on T cells.
But she and others want to see a link between cell suicide and age - related muscle loss as further evidence that a «killing factor» is at large in the body, not just the petri dish.
Preventing the ER from being overwhelmed and signaling cell suicide could be a strategy to treat MS, Popko wrote, along with University of Chicago neurologist Sharon Way, in a 2016 review article in Lancet Neurology.
To accommodate the beneficial bacteria, the nymph gut cells may actively avoid cell suicide, which, the authors hypothesize, might help CLas get in and multiply at the same time.
However, in developing brain cells, the researchers found TLR3 activation also influences 41 genes that add up to a double whammy in this model — diminished stem cell differentiation into brain cells and increased cell suicide, a carefully controlled process known as apoptosis.
This cell death bore the hallmarks of apoptosis, a controlled cell suicide that is needed for the normal development of an embryo, and to ensure that our immune system contains the correct array of cells.
More of both support cell suicide as now sick or injured cells signal mitochondria to release factors such as cytochrome c into the cell cytoplasm.
The immune misfiring and resulting cell suicide, Mongkolsapaya says, could be a primary cause of dengue hemorrhagic fever.
Knowing the structure of survivin «doesn't clear up the controversy» about how it prevents cell suicide, says biochemist Guy Salvesen of the Burnham Institute in La Jolla.
C. elegans, a 959 - celled Nobel magnet, helped explain cell suicide and launch genomics, and could now revolutionize drug development.
I can't claim any expertise in food combinations that potentiate anti-cancer effects The Nrf2 activating hormetins may prevent initiating mutations, while epigenetic modulatiors encourage transformed cell suicide or senescence and angiogenesis inhibitors starve larger tumors.
In this study, the researchers successfully targeted several proteins, including Bcr - Abl, which causes chronic myeloid leukemia; cancer cells in which that protein was disrupted underwent programmed cell suicide.
If the researchers are correct, this is the first time that abnormal cell suicide has been implicated in a parasitic disease.
In the studies led by Kanneganti, Kuriakose and colleagues first sought to identify the specific machinery that the innate immune system uses to induce cell suicide.
In turn, hyper - activated TLR3 turns off genes that stem cells need to specialize into brain cells and turns on genes that trigger cell suicide.
It looks like capsaicin is able to pull this off by instructing the mitochondria in cancer cells to undergo apoptosis, cell suicide.
The cells of these cancer - immune rats reach a point at which they die en masse in a bout of cell suicide.
Rather than ceasing to divide, the cells of blind mole rats reach a point at which they die en masse in a bout of cell suicide that Gorbunova and her co-authors call «concerted cell death».
Change of plans for Russia - bound scientists... Story Landis retires... STAP - cell suicide... astronauts and sleep... Working Life... bumblebees and discovery
Recycling is the way of nature and apoptosis, or programmed cell suicide, is the linchpin of the body's recycling program.
This triggers a domino effect in the cell's defense system, resulting in the activation of the enzyme caspase - 1, which ultimately causes the induction of pyroptosis, a fiery form of cell suicide.
The protein, called Bcl - 2, is already famed among biologists for its ability to block «apoptosis,» or cell suicide, the process by which damaged or obsolete cells destroy themselves.
Ko first cloned the human GT198 gene while a postdoctoral fellow at Harvard Medical School, and subsequent studies by her and others have shown it has multiple roles that also include regulating stem cells, cell suicide and turning other genes off and on.
According to University of Helsinki scientist and Finnish Academy Research Fellow Juha Klefström, PhD, who led the study, «Myc oncoprotein not only boosts tumor cell proliferation but it also makes the cells vulnerable to cell suicide program, apoptosis.
ABT - 737 targets proteins known as B - cell lymphoma 2 (Bcl - 2) and Bcl - xL, which prevent apoptosis, a form of cell suicide, in cancer cells.
Cell suicide is an important part of the body's defences against cancer (see «Making friends with death - wish genes», New Scientist, 30 July 1994).
The cell nuclei become fragmented, and some cells will even undergo apoptosis — auto - induced cell suicide.
Plant defenses — which can include induced cell fortification, cell suicide, toxic chemicals, and defensive enzymes and proteins — typically were sufficient to keep the infection in check, but not strong enough to eliminate it.
Myc cancer gene empowers tumor cells to relentlessly divide but simultaneously, provokes a cell suicide process called apoptosis.
«Both the immune system and nearby healthy cells send signals instructing damaged and unhealthy cells to undergo apoptosis, which is like programmed «cell suicide».
Ian Jarrold, Head of Research at British Lung Foundation said: «Although still early days, this study is a significant step forward in that it is the first time a drug has been observed causing so - called «cell suicide» in mesothelioma.
Bcl - 2 proteins play a key role in cell survival by protecting against a form of cell suicide known as apoptosis.
Earlier research had shown that cells surrounding an HIV - infected cell die as a result of apoptosis, or programmed cell suicide, and scientists knew that Nef had a hand in starting that process.
On closer inspection Håkansson noticed the cells had died as a result of a process called apoptosis — programmed cell suicide — which is one of the ways that the body gets rid of unwanted or damaged cells.
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