Sentences with phrase «cell supporting microenvironment»
The particular focus will be the role of the stem cell supporting microenvironment and its potential translation into biotechnological applications.
http://www.eurosystemproject.eu/ Not exact matches
«Taken together, these results support the hypothesis that multiple myeloma cells express bone - related genes in a Runx2 - dependent fashion that mimics bone marrow resident cells and likely contributes to tumor survival and growth in the bone microenvironment,» Yang and colleagues wrote in the paper.
In this rewriting of the textbooks, a tumor is not just a clump of aberrant cells; it also includes a support system, a tumor microenvironment, which encompasses a multitude of varying immune cell types and crisscrossing chemical signals, along with a network of blood vessels.
Contained in spongy bones, the bone marrow microenvironment and its «niches» support production of platelets and other blood cells.
«Preclinical results support entinostat's role in targeting the tumor microenvironment: Entinostat inhibits function of myeloid derived suppressor cells resulting in enhanced antitumor effect in murine models of lung and renal cell carcinoma.»
Requirement for IRF - 1 in the microenvironment supporting development of natural killer cells.
Furthermore, these potentials are expanded by the notion that MSCs can exert functions other than those classically attributed to stem or progenitor cells, including establishment and support of the hematopoietic microenvironment in vivo, as observed for bone marrow derived MSCs.
The team is also studying changes in the tumor microenvironment — the cells that support cancerous cells in a tumor — to see if there are changes and the environment is more or less «inhabitable» following treatment.
The tumor microenvironment provides a niche that supports cancer cell invasion and proliferation.