Sentences with phrase «cell surface protein genes»

Upregulated genes clustered into at least 7 functional groups, including immediate early genes or transcription factors, cell - cycle related genes, stress - responsive protein genes, cell signaling protein genes, cell adhesion and cell surface protein genes, genes involved in translation and protein turnover, and genes encoding metabolic proteins.

Not exact matches

When similar analysis was performed on the db mice, it was found that the disrupted db gene was responsible for encoding a protein that functions as a leptin receptor: When it binds circulating leptin at the cell surface, it sets in motion a biochemical cascade inside the cell.

The protein expressed by the gene is thought to bind to serotonin receptor molecules and ferry them to the cell surface, positioning them to receive serotonin's signals from neighboring cells.

Before Krieger started tinkering with the mouse gene SCARB1, he had identified SRB1, a protein found on the surface of the liver cells, as that dock for HDL.

They did this by attaching the HREs to structural genes that create a protein that can be detected on the surface of cells.

That gene encodes a sugar - studded protein on the virus's outer surface that helps the virus stick to and invade human cells.

Pcdhαc2 is found in a cluster of genes that contain the blueprints for proteins that protrude from the surface of cells.

How it hides: In a normal cell, genes encode instructions for surface proteins known as the major histocompatibility complex (MHC).

The hybrid virus is created by adding HIV RNA, a stripped - down version of the Ebola surface protein RNA and the therapeutic gene to cells.

The ADGRE2 gene provides instructions for production of ADGRE2 protein, which is present on the surface of several types of immune cells, including mast cells.

Most resistance genes, in wheat and other plants, code for protein receptors located inside cells; the Stb6 gene codes for a receptor protein on the cell's surface.

In clinical trials already underway, for example, researchers have used an older gene - editing technique, enzymes call zinc finger nucleases, in immune cells to deactivate the gene for CCR5, a surface protein that HIV latches onto in order to infect cells.

The virus inserts the therapeutic gene into the cell's DNA and uses its instructions to produce a receptor protein — a modified version of a common glutamate receptor ion channel - that they display on their surface.

Karl Deisseroth of Stanford University, and colleagues, inserted into mice the gene which codes for the algal protein ChR2, which caused the protein to attach itself to the surface of nerve cells.

In 2006, researchers discovered the genetic defect behind FOP: A mutated version of the gene ACVR1, which in patients produces an overactive form of a cell surface protein called a transmembrane receptor.

When these three genes do not function correctly, abnormalities occur in the sugar molecules that bind to the dystroglycan protein on the surface of muscle cells.

Both genes code for proteins that function as growth factor receptors, meaning they sit on the surface of cells and, when activated, can spur the rapid cell growth that is a hallmark of cancer.

Additional experiments, including gene knockdown, surfaced prohibitin as a likely infection aide; prohibitin is a multi-functional protein found in human cells and in many other organisms.

The researchers utilized a technique known as exon skipping, a form of RNA splicing, to eliminate the portion of one of the IgE receptor gene's mRNA that is essential to making a protein which places the IgE receptor on the mast cell surface.

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family.

Researchers in the laboratory of Richard A. Axel, including Leonard Chess and Dan Littman, clone the genes for the CD4 [i] and CD8 [ii] T cell surface proteins.

He isolated the genes encoding proteins that confer immunological identity to the two main types of cells in the human immune arsenal: the CD4 protein, which dots the surface of helper T cells, and the CD8 protein, which adorns killer T cells.

One of the viral genes, env, specifies a protein that forms the viral envelope, the outer covering of the virus that interacts with a target receptor on the surface of lung cells.

A cell - surface antibody panel was created and used for protein profiling alongside gene expression profiling.

This type of «killer» T cell responds to previously encountered cell - surface molecules — including the fragments of SIV proteins encoded by the genes in the CMV / SIV vaccine — and destroys SIV - infected cells.

The experiments identified a previously uncharacterized gene as essential for intoxication by diphtheria toxin and exotoxin A toxicity, and a cell surface protein needed for cytolethal distending toxin toxicity.

Known as MHC (Major Histocompatibility Complex) genes, they code for cell surface proteins.

Intestinal permeability was assessed by Ussing chamber; epithelial cell (EC) ultra-structure by electron microscopy; RNA expression of genes coding for junctional proteins by Q - real - time PCR; immune response by in - vitro antigen - specific T - cell proliferation and cytokine analysis by cytometric bead array; intestinal microbiota by fluorescence in situ hybridization and analysis of systemic antibodies against intestinal microbiota by surface staining of live bacteria with serum followed by FACS analysis.

The Major Histocompatibility Complex (MHC) is a region of the genome that contains genes that code for a group of cell surface proteins known as Dog leukocyte antigens (DLA).

The Major Histocompatibility Complex (MHC) is a region of the genome in dogs that contains genes that encode a group of cell surface proteins known as Dog leukocyte antigens (DLA).

Like the bacteria that cause gonorrhea, members of T. pallidum have multiple copies of the gene coding for the proteins that allow them to adhere to human cells — perhaps, as in the case of gonorrhea, these genes allow T. pallidum to alter their surface proteins in order to escape recognition by the immune system.