Sentences with phrase «cell surface receptor called»

Another lab ran into a similar problem when it tried to replicate work by Stanford stem cell biologist Irving Weissman and his colleagues, who reported in 2012 in the Proceedings of the National Academy of Sciences that an antibody to a tumor cell surface receptor called CD47 can slow tumor growth in mice.

In this study, we examined the effectiveness of a vaccination targeting tumors that produced IL - 15 and its cell surface receptor called IL - 15R - alpha -LRB--RRB- and examined their ability to up - regulate (or increase) immune responses to tumor antigens,» Morris says.

«Beta blockers may lead to new novel triple negative breast cancer treatments: New research suggests that adrenaline can act on tumor cells via a cell surface receptor called the beta2 - adrenoceptor and that changes in signaling within the cell make it highly invasive.»

Not exact matches

The antibody binds to a protein on the surface of T cells called the PD - 1 receptor.

The immune system depends on molecules called T cell receptors on the surface of T cells to recognize and respond to foreign antigens from virus - infected cells, tumors and other threats.

Called TSH for short, this hormone attaches to a receptor on the thyroid cell surface, triggering a series of signals that provoke the gland to pump out thyroid hormones.

One key gene encodes the making of a receptor called TREM2, a docking site for molecules on the surface of microglia and other innate immune cells.

Endocannabinoids act on a group of cell - surface molecules called cannabinoid receptors that help to regulate appetite, mood and memory.

A critical discovery in this research was finding that the novel progenitor has a receptor protein on its cell surface called KDR, or vascular endothelial growth factor receptor 2, which until now, was thought to be restricted to endothelial cells that form vessels, the progenitors for endothelial cells and the progenitors blood cells.

Liang Xu, Ph.D. member of the KU Cancer Center's Drug Discovery, Delivery and Experimental Therapeutics program and associate professor of molecular biosciences at KU, has discovered that targeting a cell - surface receptor called «CD44s» can block pancreatic tumor formation and recurrence after radiotherapy.

The engineered protein has two ends: one activates T cells by binding to a surface molecule called the CD3 receptor, and the other — based on an antibody called VRC07 — powerfully binds to more than 90 percent of HIV strains.

When PDGF arrives at the cell surface, it binds to a protein called PDGF receptor tyrosine kinase (PDGF RTK).

pAPCs express toll - like receptors on their surfaces that recognize and trap molecular patterns called antigens on bacteria, food and our own cells.

MERS CoV (CoV stands for coronavirus) has on its surface an array of spike - shaped proteins that bind to host cells — specifically to receptor proteins called DPP4 on the surface of cells that line human airways.

Think of brain cells as rooms with locks called receptors on their surfaces and a hypocretin as a key that is also a stimulant.

The scientists also found that endothelial cells themselves give the signal for their own death: To do this, the vascular wall cells have a receptor molecule called Death Receptor 6 (DR6) on their receptor molecule called Death Receptor 6 (DR6) on their Receptor 6 (DR6) on their surface.

HER2 - positive breast cancer, which is associated with poor prognosis, has been traced to an excess of signaling through receptors, or docking ports, called HER2 found on the surface of certain mammary epithelial cells.

The engineered cells contain an antibody - like protein known as a chimeric antigen receptor (CAR), which is designed to bind to a protein called CD19 found on the surface of B cells, including the cancerous B cells that characterize several types of leukemia.

In 2006, researchers discovered the genetic defect behind FOP: A mutated version of the gene ACVR1, which in patients produces an overactive form of a cell surface protein called a transmembrane receptor.

Both endorphins and opioids latch on to proteins called opioid receptors on the surface of nerve cells.

The outer surface of many of our cells, including those in the airways, has a protein called the H1 receptor.

The drug tested is an antibody that blocks a receptor called PD - 1 on the surface of the immune system's T cells.

Adenosine helps to sustain such cells by fitting into a protein called the A2A adenosine receptor on their surfaces, like a key into a lock.

IL - 33 stimulates cells by latching on to a receptor protein on their surface called ST2.

T - cells recognize and remove germs using a molecule on their surface called the T - cell receptor.

This physical change causes adhesion receptors on the cell surface called integrins to clump together.

To devise a potential new therapy, the investigators engineered a population of neural stem cells to express a potent version of a gene called TRAIL, which codes for a molecule that activates cell - death - inducing receptors found only on the surface of cancer cells.

For example, T - cells have a receptor on their surface called PD - 1, which acts as an off switch.

On the surface of every cell in your body, there are lots of small proteins that are called receptors.

Miller's group, including postdoctoral fellow Dr. Sharath Rai, graduate student Vladimir Vigdorovich and collaborators at the National Cancer Institute, identified the human version of the viral receptor, a cell - surface protein called HYAL2 that has been implicated in lung cancer.

All cells have unique proteins on their surface called receptors.

Whitehead Institute researchers have uncovered a novel association between two fungal recognition receptors on the surface of certain immune cells, called macrophages.

The researchers found that when they dosed cells that expressed a2C - AR with chemicals that activate Rap1A, either directly or through means that involve another protein called Epac, the cells drew from pools of a2C - AR near the cell's nucleus and moved these receptors to the cell surface.

He will now investigate a set of molecules called TLR agonists that act through receptors on the surfaces of innate immune cells to set off a chain reaction of molecular signaling and activation within the immune system, which includes activation of latently infected CD4 cells.

This process involves inserting a «chimeric antigen receptor (CAR),» a protein that binds to a cell - surface marker called CD19, found on many leukemic cells.

The Minnesota team also found that hemangiosarcoma cells with a high surface expression of a protein called colony - stimulating factor 1 receptor (CSF - 1R) were the culprits in this process.