Not exact matches
The researchers found that POSTN acted through a specific
integrin receptor that was present on the
surface of many BLBC
cells.
The networks provide structural integrity to tissues and serve as ligands for
integrin cell -
surface receptors.
They found that the mutated G1 and G2 variant did so particularly well on what's known as a
receptor on the
surface of kidney
cells, in this case the suPAR activated
receptor alphavbeta3
integrin.
This physical change causes adhesion
receptors on the
cell surface called
integrins to clump together.
The team chose
integrin receptors that control a variety of functions on the
cell surface as a target for their peptides.