Sentences with phrase «cell surfaces by»

A Postdoctoral Research Associate Position is available funded by the Wellcome Trust, to study the nanoscale organisation of human immune cell surfaces by super-resolution fluorescence microscopy.

But if the mutant CF protein had been elevated to the cell surface by a corrector candidate drug, then genistein, as the doorman, would open the channel and allow chloride in and out, making the cells glow blue.

The interferon - induced protein BST - 2 restricts HIV - 1 release and is downregulated from the cell surface by the viral Vpu protein.

BST - 2 is rapidly down - regulated from the cell surface by the HIV - 1 protein Vpu: evidence for a post-ER mechanism of Vpu - action.

Not exact matches

«What we have described as globalization is remarkably close to Teilhard de Chardin's planetization, in which «[mankind, born on this planet and spread over its entire surface, come [s] gradually to form round its earthly matrix, a single, major, organic unity, enclosed upon itself.4 Thus the globalization of humankind could lead to the formation of a new kind of living entity — a social organism — on the same cosmic principle as that by which atoms join to form molecules, molecules join to form mega-molecules, mega-molecules unite to form living cells, and innumerable cells constitute an organism.

In particular, the PTPRF gene, which is known to suppress intracellular signals that are usually triggered by insulin binding to its receptor on the cell surface, may serve as a biomarker linking insulin resistance with insufficient milk supply.

These experiments were complemented by genetic manipulations in which some mice were engineered to lack a gene known as Tap1, which is crucial for the MHC I complex to make its way to the cell surface.

The protein expressed by the gene is thought to bind to serotonin receptor molecules and ferry them to the cell surface, positioning them to receive serotonin's signals from neighboring cells.

«We discovered that Neu1, a protein nicknamed after «neuraminidase 1,» turns the absorption of sugar «on» or «off» in body cells, by regulating the amount of sialic acid on the surface of cells,» Dr. Pshezhetsky explains.

Macrophages were dry - fractured by touching the cell surface with cellophane tape after critical point drying to reveal intracellular bacteria.

The investigators found that CCL28, which is over-produced in joints affected by rheumatoid arthritis, attracts the surface - lining cells that carry its receptor.

«By the use of high magnification we show that the skin cells suffer from shrinkage and therefore change their surface.

By measuring how the light has changed once it emerges through the other side of the slide, the researchers can detect and monitor processes occurring on the sensor surface, such as cell division.

By hindering LMPTP, the drug reawakens insulin receptors on the surface of cells — especially in the liver — which normally absorb excess sugar from the blood when they detect insulin.

The paper, by V. Hegenauer at University of Tübingen in Tübingen, Germany, and colleagues was titled, «Detection of the plant parasite Cuscuta reflexa by a tomato cell surface receptor.»

The experiments included sorting immune cells found at injury sites by molecules on their cellular surfaces, and many hours looking at mouse cells through the microscope.

We show that H274Y decreases the amount of neuraminidase that reaches the cell surface and that this defect can be counteracted by secondary mutations that also restore viral fitness.

Next, the team set about regrowing the «flesh» of the organ by coating the inner surfaces of the scaffold with new cells.

The scientists observed that transmission of chemical signals between the nerve cells are facilitated by AMPA - receptors and the activity occurs on the brain cell surface.

This interacted with proteins on the cell surface called proteoglycans which led to the nanoparticles being ingested by the cell.

The drug works by targeting a protein carried on the surface of about 90 percent of AML cells.

A technique that peppers the cells» surface with nanoscale domes could curb this tendency and improve efficiency by as much as 25 per cent.

Q1s create the pore that the potassium flows through and the E1s control how slowly that pore opens and closes, how many channels are on the cell surface of each cell and how they are regulated by drugs.

They also showed that the cells have most of the surface «markers» considered as identifiers of embryonic stem cells and form «embryoid bodies» — characteristic clumps of cells formed by ESCs.

CRH, in turn, triggered production of the cell surface protein FasL; trophoblasts expressing FasL then form a protective shield of sorts around the embryo by forcing any attacking immune cells to self - destruct.

They did this by attaching the HREs to structural genes that create a protein that can be detected on the surface of cells.

Previous studies have found that brown fat can be coaxed into action by activating the β3 - adrenergic receptor, which is expressed on the surfaces of brown and white fat cells, as well as on cells of the urinary bladder and other tissues.

It is controlled, in part, by a series of channels on the surface of heart cells that regulate the movement of different ions into and out of the cells.

What they discovered was that an inflammatory factor known as TGF - beta (transforming growth factor - beta) can give cancer cells properties of immune cells by supplying the surface of the cancer cell with a receptor that normally only exists on the white blood cells that travel through the lymphatic system.

King hypothesizes that proteins that the single - celled ancestors of animals used to interact with the extracellular environment — to capture bacterial prey by binding to their cell surface and to detect chemical signals — were later repurposed to enable cells to stick to and talk to each other.

The mushroom - shaped protein specializes in infecting cells, first by binding a trio of sites on its head to three separate sugar molecules on the surface of targeted cells.

Water has energy to do work: it carries chemicals in solution, adheres to surfaces and makes living cells turgid by filling them.

They identified these cells by looking for cell surface proteins called CD31 and CD146.

The target Porter and June ultimately chose was CD19, a protein on the surface of B cells only, discovered by researchers at Harvard Medical School in the 1980s.

An animal's immune system detects foreign cells by scanning for proteins, called antigens, that stick out from the surface of each cell.

In particular, it has evolved to show itself three to nine months after infection, allowing its own destruction by displaying antigens on its cell surfaces so the dog's immune system can destroy it.

This was done by identifying amounts of thousands of individual proteins on the surface of the cell.

By latching onto receptors on the surface of T lymphocytes, gp120 allows the virus to enter the cells and reproduce.

«By determining the charge of a virus, for example, you can understand how it can be transported to the cell surface.

Research led by Sandia National Laboratories and the University of California, Merced aim at bringing down the cost of hydrogen fuel cells by using a dirt - cheap compound to create an uneven surface that resembles a plant's leaves.

Researchers at Harvard T. H. Chan School of Public Health and the Broad Institute have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite.

By mimicking the stiffness of bone (40 kilopascal) or cartilage (15 kilopascal), the gel causes stem cells applied to its surface to differentiate.

The hybrid virus is created by adding HIV RNA, a stripped - down version of the Ebola surface protein RNA and the therapeutic gene to cells.

The fact that the surface could be stretched meant that the parameters of the unit patterned cell can be actively controlled by stretching.

Scientists have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite.

The engineered protein has two ends: one activates T cells by binding to a surface molecule called the CD3 receptor, and the other — based on an antibody called VRC07 — powerfully binds to more than 90 percent of HIV strains.

The key discovery made by the CSHL team is that FER is able to activate a receptor on the surface of ovarian cells «from below,» as it were — by interacting with a portion of the receptor that penetrates the cell membrane and plunges into the cytoplasm.

disruption of the cell wall barrier by reactions of chlorine with target sites on the cell surface

T - lymphocyte cells are distinguished by surface markers.

The toxins overcome the cell membrane by binding to a surface receptor, which conveys them into the cell's interior.