Sentences with phrase «cell survival when»

Not exact matches

Similar to capsaicin, tumor necrosis factor is suspected to both induce and reduce cancer cell growth, and was shown to commit cells to survival when stimulating EGFR transactivation mechanisms, indicating that EGFR could act as a molecular switch determining the antiapoptotic effect of tumor necrosis factor (50).

Furthermore, when healthy neurons in a dish were treated with serum from the patients and antibodies against leiomodin - 1, they did not survive, but removing the antibodies increased brain cell survival.

The investigators utilized a targeting method called RNA interference (RNAi) which, when delivered via these natural nanoparticles or exosomes, zero in on mutant KRAS in pancreas cancer cells, impacting tumor burden and survival in multiple pancreas cancer models.

Drs. Prud «homme and Wang also found that GABA vastly improved the survival rate of pancreatic cells when they were being transplanted into mice.

PKC serves as the brakes to cell growth and survival, so cancer cells benefit when PKC is inactivated.

When BRCA1 is mutated, ANG1 switches on, new blood vessels are formed, and cancer cells get the nutrients critical to their survival.

«If we could perhaps modulate these pathways and prolong survival of photoreceptor cells, we might be able to delay any further degeneration even when intervening at these later stages of disease.»

When we experimentally increased the expression of the microRNAs in model nerve cells designed to replicate the conditions of HD, the cells lived longer, indicating that these miRNAs may promote cell survival,» explained lead author Richard Myers, PhD, professor of neurology at BUSM.

«When cells are stressed, for example when nutrient levels are low, they alter protein production as a survival stratWhen cells are stressed, for example when nutrient levels are low, they alter protein production as a survival stratwhen nutrient levels are low, they alter protein production as a survival strategy.

When optimal temperatures are restored, the plant stem cells can divide at a faster rate, which will in turn enhance recovery and survival of the plant.»

In a study recently published in the journal Cytotherapy, researchers in India discovered that treating mice with a common anti-inflammatory drug called celecoxib promoted stem cell survival and healing when they injected the cells into wounds.

Researchers have found that people with advanced head and neck squamous cell carcinoma and the KRAS - variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab in combination with standard chemotherapy and radiation.

But when the researchers added a phage that targets E. coli to the cultures, survival rates skyrocketed for the mucus - producing cells.

The immunotherapy drug pembrolizumab, when combined with chemotherapy, doubles survival in patients with non-squamous non-small cell lung cancer (NSNSCLC) lacking genetic changes in the EGFR or ALK genes, when compared to...

With regard to HgT, a molecular analysis of cybrid cells with identical nuclear backgrounds and different mtDNA populations indicated that HgT cybrids had a higher survival rate and were more tolerant of oxidative stress when compared to the more common European haplogroup H [45].

DENVER — Elderly patients with stage III non-small cell lung cancer (NSCLC) showed improved overall survival (OS) when treated with chemoradiation (CRT) compared to definitive radiation (RT) alone.

As a control, irradiation of wild - type mice resulted in 100 % mortality after a period of 9 months after irradiation, when the mice were 11 months old (Fig. 3 ⇓ shows the survival curve of the females alone for the purpose of simplifying the discussion below); and mortality was mainly attributable to the development of T - cell lymphomas (Table 3) ⇓.

Vincent, who has referenced Duesberg's theory in his own papers, believes that cancerous cells exploit an ancient survival mechanism, reverting to the form of protozoa - like organisms from before the time when single cells began cooperating to create multicellular organisms like us.

Proto - oncogenes consist of a group of genes / proteins that, when expressed, normally encourage cell survival, growth and proliferation, while tumor suppressors perform the opposite task, keeping cells from dividing out of control.

Research efforts led by Dr. Elizabeth Lawlor are studying how Ewing sarcoma cancer cells are able to survive when deprived of oxygen, and whether suppression of specific proteins can address this abnormal cell survival and lead to better outcomes for patients.

Importantly, when mice received lethal doses of host - type acute leukemia cells, administration of VPA did not impair GVL activity and resulted in significantly improved leukemia - free survival.

When introduced into the MDA - MB - 231 cells, the Δ2A mutant did not induce apoptosis of these cells whereas WT LARP7 readily impaired cell survival, supporting the model that the ability of LARP7 to assemble 7SK snRNP and suppress P - TEFb is necessary for its tumor suppressor potential.

When ketone bodies have been used in animals and cell cultures, they have demonstrated neuroprotective qualities such as improving cell survival and cognitive performance (1).

Unlike the Naruto: Ultimate Ninja Storm series which is more and more a mess of technical, balance and gameplay issues these days, Brave Soldiers delivers what is a nice, franchise - based fighting game, at first, i was expecting a simple fighting game with some button mashing, however, the game proved me wrong and i fell in love, the combo system, while easy, is a lot more deep than the one in the Naruto games, with all of the characters having two special attacks, two «burst attacks», a knock - away and a launcher respectively, a throw and an ultimate attack (called a «Big Bang Attack»), every character also has an universal dodge - action that sends them behind their enemies while spending one cosmo bar, making bar management that much precious and shielding you from a half - a-hour combo, unlike in the NUNS series, the fighting and the characters are nicely balanced, with every character being fun to play and viable at the same time, the game runs smoothly without frame - rate issues and the cell - shaded graphics, character models, arenas and effects alike are nice to the eye, battles are divided into rounds, with all the tiny nice stuff like character introductions and outros being intact (fun fact: the characters will even comment on their score after the battle), the game also features an awakening system, called the «Seventh Sense» awakening, unlike the NUNS awakening system which became severely unbalanced in the later game, every character simply gains a damage / defense boost, with the conditions being the same for all characters, eliminating situations when one character can use awakening at almost any point in the battle, or one awakening being drastically stronger than the other, the game has a story mode with three story arcs used to unlock characters, a collection mode, tournament modes, a survival mode, a series of special versus modes and online battle modes.

Hydrogen - powered fuel - cell development programs fell off the automotive radar screen when the global economy faltered in 2008 and automakers focused on immediate survival rather than future products.

It has been proven that when you place the Reticare protective sheet over electronic devices screens the survival rates of retina cells increase up to 83 %.

When you get into the cell after being tortured go into the survival viewer, and press R1 to look at snake closer.

When Wayne Campbell was diagnosed with small cell lung cancer, he was given a one in 10 chance for survival.