Sentences with phrase «cell transfer of»

A University of California at Los Angeles (UCLA) study headed by Antoni Ribas, M.D., Ph.D., is a first - in - human phase I clinical trial combining adoptive cell transfer of a T cell receptor engineered to recognize NY - ESO - 1 along with Yervoy ® (ipilimumab, anti-CTLA-4).

However, adoptive cell transfer of TILs did mediate the objective complete response of 24 % of patients.

Adding total body irradiation to preparative lymphodepletion chemotherapy prior to the adoptive cell transfer of tumor - infiltrating lymphocytes (TILs) had no effect on tumor regression in patients with metastatic melanoma, according to the results of a study published in the Journal of Clinical Oncology.

Cell - to - cell transfer of a virus (as opposed to a virus jumping from one infected cell to another) is believed to be as much as 1,000 times more effective at spreading pathogens.

Not exact matches

Laptops, Personal Digital Assistants (PDAs), and Blackberries (wireless cell phone and PDA units) use wireless data transfer technologies to provide users with almost instant access to information stored on a company's computer networks and servers from just about anywhere within reach of a cell phone tower or wireless Internet transmitter.

Nanoengineers might dig into the molecular structure of battery materials to speed up how they transfer more voltage per cell.

OAR proponents claim that when the altered donor - cell nucleus with its activated nanog gene is transferred to the enucleated oocyte (egg cell), the presence of nanog will immediately convert the enucleated egg cell to a pluripotent cell, without ever forming a zygote.

The OAR proposal uses a variation of therapeutic cloning called altered nuclear transfer (ANT) in which the nucleus of a donor cell (a skin cell, for example), containing the 30,000 genes of the genetic code, is altered in such a way that it produces an epigenetic factor, a protein called nanog.

If ESCR using «excess» embryos from IVE» continues, the next step will likely be the pursuit of such «therapeutic» cloning — the creation of embryos through somatic cell nuclear transfer (SCNT) to provide individually tailored stem cell therapies.

One proposal that has received considerable scientific support has been to generate non-embryonic entities that can serve as a source of stem cells through a process termed Altered Nuclear Transfer (or ANT).

DeGette's confusion about somatic cell nuclear transfer dovetails nicely with one of Levin's earlier points.

It is clear that the transfer media trance has fully consumed every cell in the bodies of some fans.

This may entail making small holes in the bone to allow new cartilage to grow (microfracture), taking cartilage from another part of the athlete's knee and transplanting it into the defect (osteochondral autograft transfer), taking cartilage cells from the knee and then having them grown in a lab for later re-implantation (autologous chondrocyte implantation), or taking cartilage from a person who has passed away and placing it in the defect (osteochondral allograft transfer).

Certain bioactive substances and live cells in milk appear to influence neonatal gut maturation and growth through their transfer of developmental information to the newborn.

Their little bodies produce the extra bilirubin to help pass these extra cells but often due to a bit of a traffic jam at the liver, the excess bilirubin is transferred to the blood and stored in the skin, thus resulting in the yellow tint.

They had to have very robust immune systems to survive, and transfer of antibodies and cells through their milk probably contributed greatly to the survival of royal babies.

Some of these changes happen in the final weeks of pregnancy, including the stage when red blood cell production is transferred from the liver to the bone marrow.

In this process, the nucleus of a donor adult cell is transferred to an egg whose nucleus, and thus its genetic material, has been removed.

The release of a unanimous U.S. Supreme Court decision dictating that police need a warrant in order to search a cell phone coincides with a request by the Buffalo Police Department to purchase equipment that would transfer all data from a cell phone so it could be examined by detectives.

If an individual's turbines or panels produce an excess of energy, it can be transferred to other customers in the grid or stored in fuel cells until it is needed.

Last night, my State Governor, Dr. Abdulfatai Ahmed revealed to me an information at his disposal that a group of suspects who had been in police cells for several weeks for cultism and whose investigation had been concluded with prosecution about to commence under the State law based on the advice of the Director of Public Prosecution (DPP) and the Ministry of Justice were ordered to be transferred to Abuja this morning.

One of the latest twist of the story told on Wednesday was by Senate President Saraki who announced that his State governor and ally, Abdulfatai Ahmed had told him that a group of suspects who had been in police cells for several weeks for cultism and whose investigation had been concluded with prosecution about to commence under the State law based on the advice of the director of public prosecution (DPP) and the Ministry of Justice, were ordered to be transferred to Abuja on the directive of IGP) Idris Ibrahim.

To help make ideas about energy more concrete, for example, the new unit will use a variety of analogies from more familiar physical systems (e.g., combustion and charging a cellphone battery) to help students understand those same energy - releasing and energy - requiring chemical reactions and energy transfer when they occur in living organisms (e.g., cellular respiration, creating a charge across a membrane in mitochondria and nerve cells) where the reactions are more complex and difficult to observe.

Over 20 species of mammals have been cloned via somatic cell nuclear transfer — including cats, dogs, rats and even a camel (SN: 3/23/02, p. 189).

But this type of cloning has little in common with somatic cell nuclear transfer.

Microchimerism most commonly results from the exchange of cells across the placenta during pregnancy, however there is also evidence that cells may be transferred from mother to infant through nursing.

They all use RNA molecules as messengers to transfer the information from DNA to cellular factories called ribosomes, which then build proteins, which in turn drive our metabolisms and form the structures of our cells.

To solve this, West proposed «therapeutic cloning» — taking the nucleus out of a patient's cell, transferring it into an egg cell to create a cloned embryo, then using that embryo to derive patient - matched stem - cell lines.

Focusing on energy - transfer, they measured the impact on cell lines in a laboratory of 7 substances, the clinically - approved drug stiripentol, 3 natural products — caffeic acid phenyl ester (CAPE), silibinin and ascorbic acid — and experimental pharmaceuticals, such as actinonin, FK866 and 2 - DG.

This summer Wagers published research [subscription required] showing that when muscle stem cells were transferred into mice with a type of muscular dystrophy, the rodents» muscle function improved.

Thus, transport of peptide — MHC II complexes by DCs not only accomplishes transfer from late endocytic compartments to the plasma membrane, but does so in a manner that selectively concentrates TCR ligands and costimulatory molecules for T cell contact.

Within a few days of the stem cell procedure, Boesen was transferred to Keck's rehabilitation unit.

Yifan Dai of the University of Pittsburgh and his colleagues first transferred the roundworm gene — fat - 1 — to pig fetal cells.

In this study, Cherqui's team transplanted wildtype HSPCs into an FA mouse model, reporting that the HSPCs engrafted and soon differentiated into macrophages in key regions of the mice's brain and spinal cord where they appeared to transfer wildtype FXN into deficient neurons and muscle cells.

«What we want this technology to achieve is confidence to switch to single embryo transfers instead of the practice of transferring multiple embryos without [an accompanying] reduction in pregnancy rate,» study co-authors Gayle Jones and David Cram, senior research scientists in immunology and stem cells at Monash University in Australia, wrote in an e-mail.

In this reconstituted schematic, hematopoietic stem cells (HSC) transplanted in a mouse model of Friedreich's ataxia differentiate into microglial cells (red) and transfer mitochondrial protein (green) to neurons (blue), preventing neurodegeneration.

Rodríguez - Perales, Torres and Ramírez have shown that by transferring the RGEN components into primary human cells, regions of the exchanged chromosomes in some tumours can be marked, thus generating cuts in those chromosomes.

This compound mediates the transfer of electrons from the biological membranes to the electrical circuit, enabling the creation of an electric current in the cell.

This maneuver «froze» the cells in a quiescent phase of their division cycle and may have made their chromosomes more susceptible to being reprogrammed to initiate the growth of a new organism after the nuclei were transferred into an egg.

Researchers are also experimenting with another form of immunotherapy called adoptive cell transfer, which harvests and then reintroduces patients» tumor - infiltrating lymphocytes — cells with anti-tumor capabilities that dig deep behind enemy lines.

Lots of synapses communicating between different nerve cells form networks and LTP intensifies the connectivity of the cells in the network to make information transfer more efficient.

The scheme of oxidases action is simple: transferring electrons to molecular oxygen, reducing equivalents are oxidized again, and as a result «the energy currency» of the cell — the proton - moving force is generated.

That breakthrough was one of a six - year chain of discoveries that included his 2007 work demonstrating the nuclear transfer method to create embryonic stem cells from a nonhuman primate.

The method, called somatic cell nuclear transfer (SCNT), replaces the DNA in an egg cell's nucleus with the genetic material from the nucleus of a skin cell, then tricks the egg cell to start dividing as if it had been fertilized with sperm.

In May 2013, Mitalipov was the first scientist in the world to demonstrate the successful use of somatic cell nuclear transfer, or SCNT, to produce human embryonic stem cells from an individual's skin cell.

He says that he is ready to ship the cloned ES cell lines to several labs that have requested them as soon as the Oregon institutional review board signs off on the transfers, which could happen in a matter of days.

They expected eggs to be more complex, but last year, Hayashi made PGCs in vitro with cells from a mouse with normal coloring and then transferred them into the ovaries of an albino mouse.

Even distantly related bacteria can swap genes with one another using a variety of techniques, from direct cell - to - cell transfer, called conjugation, to transformation, in which a bacterium releases snippets of DNA that other bacteria pick up and use.

CTL119 manufacturing begins with a patient's own T cells, some of which are removed and then reprogrammed in Penn's Clinical Cell and Vaccine Production Facility with a gene transfer technique designed to teach the T cells to target and kill tumor cells.

Subsequent procedures included mammalian somatic cell nuclear transfer, cell fusion, induction of pluripotency by ectopic gene expression, and direct reprogramming.